Arndt-Eistert homologation

  • Jie Jack Li


One carbon homologation of carboxylic acids using diazomethane.


Inorganic Chemistry Organic Chemistry Carboxylic Acid Side Reaction Carbon Homologation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Arndt, F.; Eistert, B. Ber. Dtsch. Chem. Ges. 1935, 68, 200.CrossRefGoogle Scholar
  2. 2.
    Kuo, Y. C.; Aoyama, T.; Shioiri, T. Chem. Pharm. Bull. 1982, 30, 899.Google Scholar
  3. 3.
    Podlech, J.; Seebach, D. Angew. Chem., Int. Ed. Engl. 1995, 34, 471.CrossRefGoogle Scholar
  4. 4.
    Matthews, J. L.; Braun, C.; Guibourdenche, C.; Overhand, M.; Seebach, D. Enantioselective Synthesis of β-Amino Acids 1997, pp 105–126.Google Scholar
  5. 5.
    Katritzky, A. R.; Zhang, S.; Fang, Y. Org. Lett. 2000, 2, 3789.CrossRefGoogle Scholar
  6. 6.
    Cesar, J.; Sollner Dolenc, M. Tetrahedron Lett. 2001, 42, 7099.CrossRefGoogle Scholar
  7. 7.
    Katritzky, A. R.; Zhang, S.; Mostafa Hussein, A. H.; Fang, Y.; Steel, P. J. J. Org. Chem. 2001, 66, 5606.CrossRefGoogle Scholar
  8. 8.
    Vasanthakumar, G.-R.; Babu, V. V. S. Synth. Commun. 2002, 32, 651.CrossRefGoogle Scholar
  9. 9.
    Chakravarty, P. K.; Shih, T. L.; Colletti, S. L.; Ayer, M. B.; Snedden, C.; Kuo, H.; Tyagarajan, S.; Gregory, L.; Zakson-Aiken, M.; Shoop, W. L.; Schmatz, D. M.; Wyvratt, M.J.; Fisher, M. H.; Meinke, P. T. Bioorg. Med. Chem. Lett. 2003, 13, 147.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

Personalised recommendations