Baylis-Hillman reaction

  • Jie Jack Li


Also known as Morita—Baylis—Hillman reaction, and occasionally known as Rauhut—Currier reaction. It is a carbon-carbon bond-forming transformation of an electron-poor alkene with a carbon nucleophile. Electron-poor alkenes include acrylic esters, acrylonitriles, vinyl ketones, vinyl sulfones, and acroleins. On the other hand, carbon nucleophiles may be aldehydes, α-alkoxycarbonyl ketones, aldimines, and Michael acceptors.


Inorganic Chemistry Organic Chemistry General Scheme Tertiary Amine Vinyl Ketone 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

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