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Bamford-Stevens reaction

  • Jie Jack Li

Abstract

The Bamford-Stevens reaction and the Shapiro reaction share a similar mechanistic pathway. The former uses a base such as Na, NaOMe, LiH, NaH, NaNH2, etc., whereas the latter employs bases such as alkyllithiums and Grignard reagents. As a result, the Bamford-Stevens reaction furnishes more-substituted olefins as the thermodynamic products, while the Shapiro reaction generally affords less-substituted olefins as the kinetic products.

Keywords

Inorganic Chemistry Organic Chemistry Mechanistic Pathway Grignard Reagent Kinetic Product 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Jie Jack Li
    • 1
  1. 1.Chemistry DepartmentPfizer Global Research and DevelopmentAnn ArborUSA

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