Abstract
Although the presence of age-related macular degeneration (AMD) can be suspected on the grounds of a patient’s history and an ophthalmoscopic examination, angiographic evaluation is the most important tool in the ophthalmologist’s armamentarium for the diagnosis and characterization of AMD and for monitoring the response to treatment. There are two principal dyes used in angiography of the eye. Fundus angiography is done with two different dyes, one of which, sodium fluorescein, is used principally for retinal angiography (Spaide 1999) and the other, indocyanine green (ICG), for choroidal angiography (Tittl et al. 1999). Fluorescein angiography was developed earlier, and more is known about the correlation between histopathology and angiographic findings with fluorescein than in the case of ICG. Therefore, fluorescein angiography serves as the prototype for learning fundus angiography. ICG angiography has become practicable more recently with the development of digital imaging systems, but the significance of many of the findings recorded with ICG angiography is not definitely known. However, ICG angiography has offered new insights into the pathophysiology of different types of choroidal neovascularization (CNV).
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Spaide, R.F. (2004). Fundus Angiography. In: Age-related macular degeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05199-3_6
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DOI: https://doi.org/10.1007/978-3-662-05199-3_6
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