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Dobutamine Stress Echocardiography

  • Chapter
Stress Echocardiography

Abstract

Among exercise-independent stresses, the most popular are dobutamine and dipyridamole. Dobutamine is the prototype of pharmacological adrenergic or inotropic stress. It was initially proposed for the diagnosis of coronary artery disease in combination with perfusion imaging [1] and later with 2-D echocardiography [2,3] (Fig.1). Other sympathomimetic agents have been proposed for stress echocardiography, including isoproterenol [4] and epinephrine [5], but these drugs often bring arrhyth-mogenic side effects. Dobutamine was first proposed in 1984 [1,2] but was later abandoned, mostly because of concern about induced arrhythmias [6]. Following the demonstration of low-dose dobutamine as a test of myocardial viability [7], in the past decade dobutamine has been extensively adopted as the most-used pharmacological test in stress echocardiography.

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Authors and Affiliations

  1. Institute of Clinical Physiology, National Research Council, Via Moruzzi, 1, 56124, Pisa, Italy

    Eugenio Picano MD, PhD, FESC (Senior Medical Researcher of Italian National Research Council, Director, Echocardiography and Stress Testing Lab Institute of Clinical Physiology, Pisa, Scientific Director Cardiology, Clinica Cardiologica Montevergine, Mercogliano, Avellino, Editor-in-Chief Biomed Central Netjournal Cardiovascular Ultrasound)

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  1. Eugenio Picano MD, PhD, FESC
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Picano, E. (2003). Dobutamine Stress Echocardiography. In: Stress Echocardiography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05096-5_11

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