Follicular Development and Apoptosis

  • H. Billig
  • E. Markström
  • E. C. Svensson
  • R. Shao
  • A. Friberg
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 41)


More than 99.9% of the ovarian follicles present at birth never reach ovulation. The most common fate of follicles is instead to undergo atresia, which has been shown to be mediated by a highly organised type of cell death called apoptosis or programmed cell death (Hsueh et al. 1994; Billig et al. 1996; Kaipia and Hsueh 1997). The final tuning of the large number of growing follicles to a single ovulatory follicle is primarily achieved by cell death of granulosa cells (Hsueh et al. 1994; Reynaud and Driancourt 2000).


Luteinizing Hormone Granulosa Cell Ovarian Follicle Follicular Development Keratinocyte Growth Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • H. Billig
  • E. Markström
  • E. C. Svensson
  • R. Shao
  • A. Friberg

There are no affiliations available

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