Flat Membrane Bioreactor for the Replacement of Liver Functions

  • L. De Bartolo
  • A. Bader
Conference paper
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 35)


Each year in the U.S., approximately 150,000 people are hospitalised with liver disease and over 43,000 people die from it (Langer and Vacanti 1993). These numbers are expected to increase as the 4 million people currently infected with Hepatitis C advance to liver failure. Transplantation, the only effective means of treating liver failure, is not an option for many patients. Some are simply not sick enough to justify the massive cost, invasiveness and risk of a transplant, leaving them unaided today. Other patients are too sick to qualify, while others die awaiting a transplant.


Hepatic Encephalopathy Acute Liver Failure Hepatocyte Culture Liver Support Fulminant Liver Failure 
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© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • L. De Bartolo
  • A. Bader

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