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Mechanisms of Photo(chemo)therapy

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Dermatological Phototherapy and Photodiagnostic Methods

Abstract

Ultraviolet (UV) radiation has been used for decades with great success and at a constantly increasing rate in the management of skin diseases and has thereby become an essential part of modern dermatological therapy [28]. Its success as a therapeutic agent has stimulated studies about the mechanisms by which UVB and UVA phototherapy work. The knowledge obtained from this work is an indispensable prerequisite for making treatment decisions on a rational rather than empirical basis. Modern dermatological phototherapy has just begun to profit from this knowledge, and it is very likely that this development will continue and provide dermatologists with improved phototherapeutic modalities and regimens for established and new indications. This chapter aims to provide an overview about current concepts of the mode of action of dermatological phototherapy. Special emphasis will be given to studies that have identified previously unrecognized immunosuppressive/anti-inflammatory principles of photo(chemo)therapy.

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Authors
  1. Jean Krutmann
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  2. Akimichi Morita
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  3. Craig A. Elmets
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Editor information

Editors and Affiliations

  1. Clinical and Experimental Photodermatology, Heinrich-Heine-Universität, Moorenstraße 5, D-40225, Düsseldorf, Germany

    Jean Krutmann M.D.

  2. Abt. für spezielle Dermatologie und Umweltdermatosen, Universitäts-Hautklinik AKH, Währinger Gürtel 18-20, A-1090, Wien, Austria

    Helmut Hönigsmann

  3. Department of Dermatology, University of Alabama at Birmingham SDB 67, 35294-0007, Birmingham, AL, USA

    Craig A. Elmets M.D.

  4. Department of Dermatology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., 75390-9069, Dallas, TX, USA

    Paul R. Bergstresser M.D.

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© 2001 Springer-Verlag Berlin Heidelberg

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Krutmann, J., Morita, A., Elmets, C.A. (2001). Mechanisms of Photo(chemo)therapy. In: Krutmann, J., Hönigsmann, H., Elmets, C.A., Bergstresser, P.R. (eds) Dermatological Phototherapy and Photodiagnostic Methods. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04511-4_2

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  • DOI: https://doi.org/10.1007/978-3-662-04511-4_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04513-8

  • Online ISBN: 978-3-662-04511-4

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