Drug Transport Across the Blood-Brain Barrier

  • G. Fricker
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 37)


Case numbers of neurodegenerative disorders, such as Alzheimer’s disease, Morbus Parkinson, epilepsy, brain tumours or human immunodeficiency virus (HIV)-related encephalopathy, are continuously increasing, thereby causing enormous costs to the public economy. For example, following the World Health Report, more than 12 million people are suffering from Alzheimer’s disease worldwide. With more than 4 million patients at an annual expense of over US $50 billion, the disease has currently become the third largest medical problem in the United States (Friden 1996).


Brain Endothelial Cell Brain Capillary Brain Capillary Endothelial Cell Porcine Brain Brain Microvessel Endothelial Cell 
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© Springer-Verlag Berlin Heidelberg 2002

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  • G. Fricker

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