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Forum Discussion: ADME-Based Compound Optimization and Selection Paradigm

  • Andreas Baumann
  • Martin Bayliss
  • Thorsten Blume
  • Ulf Boemer
  • Gerardine Burton
  • Gabriele Cruziani
  • Karsten Denner
  • John Dixon
  • Gerd Fricker
  • Nikolaus Heinrich
  • Thierry Lavé
  • Jiunn Lin
  • Arun Mandagere
  • Geert Mannens
  • Timothy Olah
  • Olavi Pelkonen
  • Joe Post
  • Iris Pribilla
  • Andreas Reichel
  • Andrea Rotgeri
  • Herbert Schneider
  • Gerd Siemeister
  • Dennis Smith
  • Thomas Steger-Hartmann
  • Babu Subramanyam
  • Han van de Waterbeemd
  • Ron Vergona
  • Bjorn Wallmark
  • Christian Wienhold
Conference paper
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 37)

Abstract

I have a few questions relating to your filtration or artificial membrane model. Could one explanation for your poor correlation with the Caco-2 data be that you use a different solvent concentration?

Keywords

Forum Discussion Brain Endothelial Cell Intestinal Metabolism Cryopreserved Hepatocyte Cassette Dose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Andreas Baumann
  • Martin Bayliss
  • Thorsten Blume
  • Ulf Boemer
  • Gerardine Burton
  • Gabriele Cruziani
  • Karsten Denner
  • John Dixon
  • Gerd Fricker
  • Nikolaus Heinrich
  • Thierry Lavé
  • Jiunn Lin
  • Arun Mandagere
  • Geert Mannens
  • Timothy Olah
  • Olavi Pelkonen
  • Joe Post
  • Iris Pribilla
  • Andreas Reichel
  • Andrea Rotgeri
  • Herbert Schneider
  • Gerd Siemeister
  • Dennis Smith
  • Thomas Steger-Hartmann
  • Babu Subramanyam
  • Han van de Waterbeemd
  • Ron Vergona
  • Bjorn Wallmark
  • Christian Wienhold

There are no affiliations available

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