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Eph Receptor Tyrosine Kinases and Their Ligands in Development

  • Conference paper
Of Fish, Fly, Worm, and Man

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 29))

Abstract

A current focus of interest in developmental neurobiology is the identification and characterization of mechanisms and molecules contributing to the formation of neuronal connections. A number of gene families playing a role in this process have recently been identified. They can be classified tentatively according to the basic mechanisms by which axonal pathfinding to, and guidance in, the target area are thought to occur: chemoattraction by Netrins, chemorepulsion by Netrins and secreted Semaphorins; contact-mediated attraction by Ig domain-containing cell adhesion molecules (Ig-CAMs), Cadherins, and extracellular matrix proteins (ECM); and finally, contact-mediated repulsion by transmembrane Semaphorins, ECM proteins, and Ephrins (Tessier-Lavigne and Goodman 1996; Müller 1999).

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Authors
  1. U. Drescher
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Editors and Affiliations

  1. Abteilung Genetik, Max-Planck-Institut für Entwicklungsbiologie, Spemannstrasse 35/III, 72076, Tübingen, Germany

    Christiane Nüsslein-Volhard

  2. Enabling Technologies, Preclinical Drug Research, Schering AG, Müllerstrasse 178, 13342, Berlin, Germany

    Jörn Krätzschmar

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© 2000 Springer-Verlag Berlin Heidelberg

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Drescher, U. (2000). Eph Receptor Tyrosine Kinases and Their Ligands in Development. In: Nüsslein-Volhard, C., Krätzschmar, J. (eds) Of Fish, Fly, Worm, and Man. Ernst Schering Research Foundation Workshop, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04264-9_9

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  • DOI: https://doi.org/10.1007/978-3-662-04264-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04266-3

  • Online ISBN: 978-3-662-04264-9

  • eBook Packages: Springer Book Archive

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