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Application of T Cell lmmunotherapy for Human Viral and Malignant Diseases

  • Conference paper
Therapeutic Vaccination Strategies

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 30))

Abstract

Improvements in our understanding of the molecular basis for T cell recognition of virus-infected cells and tumors, and of the signals involved in eliciting and maintaining a competent immune response has led to new efforts to bolster host T cell immunity in settings where deficient responses permit disease progression. The identification of viral antigens and antigens expressed by tumors has led to efforts to develop adoptive immunotherapy with T cell clones as a therapeutic approach to restore or augment host responses (Riddell and Greenberg 1995). The early results of clinical studies of T cell therapy for viral diseases have been encouraging and this approach is now being developed for the treatment of patients with leukemia that recurs after allogeneic bone marrow transplant (BMT) and patients with solid tumors.

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Authors
  1. S. R. Riddell
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  2. E. H. Warren
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  3. D. Lewinsohn
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  4. H. Mutimer
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  5. M. Topp
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  6. L. Cooper
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  7. R. de Fries
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  8. P. D. Greenberg
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Editor information

Editors and Affiliations

  1. Department of Dermatology and Allergy, Medical Faculty Charité, Humboldt University, Schumannstrasse 20/21, 10117, Berlin, Germany

    P. Walden  & W. Sterry  & 

  2. Experimental Dermatology, Schering AG, Müllerstrasse 178, 13342, Berlin, Germany

    H. Hennekes

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© 2000 Springer-Verlag Berlin Heidelberg

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Riddell, S.R. et al. (2000). Application of T Cell lmmunotherapy for Human Viral and Malignant Diseases. In: Walden, P., Sterry, W., Hennekes, H. (eds) Therapeutic Vaccination Strategies. Ernst Schering Research Foundation Workshop, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04183-3_4

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  • DOI: https://doi.org/10.1007/978-3-662-04183-3_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-04185-7

  • Online ISBN: 978-3-662-04183-3

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