Abstract
The goal of somatic gene therapy is to therapeutically benefit an individual by transferring genetic information to non—germline cells. Genes can be transferred either to replace the function of a defective gene in order to add genetic information and thereby provide an additional function to a target cell or to suppress the function of an already active gene in the target cell population.
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Glimm, H., von Kalle, C., Henschler, R., Mertelsmann, R. (1998). Hematopoietic Ex Vivo Gene Transfer. In: Sobol, R.E., Scanlon, K.J., Nestaas, E. (eds) Gene Therapy. Ernst Schering Research Foundation Workshop, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03577-1_10
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DOI: https://doi.org/10.1007/978-3-662-03577-1_10
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