Epididymal Proteins and Sperm Maturation

  • Trevor G. Cooper
Part of the Schering Foundation Workshop book series (SCHERING FOUND, volume 4)


It is appropriate that a Testis Workshop should have as an accessory appendage a session on the epididymis, for the mere production of sperm cells is insufficient for fertility and a period of extra-gonadal maturation and storage of spermatozoa is necessary. There have been recent advances in several areas of epididymal physiology and biochemistry and I shall address two of them. The main growth area, to which most of this review is devoted, is the identification of protein secretion products of the epididymal epithelium and their localization in the epididymis on epididymal spermatozoa and their putative rôles in fertilization. The epididymis is also responsible for modifying proteins already on the sperm when they enter the epididymis. Demonstrations of changes in the ability of sperm to respond to stimulation upon maturation have also provided clues as to what events occur to them in the epididymis.


Acrosome Reaction Sperm Maturation Mouse Sperm Human Epididymis Epididymal Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Trevor G. Cooper

There are no affiliations available

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