Abstract
Atopy is a constitutional state defined by the genetically determined disposition to develop atopic eczema, allergic rhinoconjunctivitis, and/or allergic asthma. Up to now, no definite marker has been available which would allow one to decide with certainty whether atopy is present or absent in a given individual. This hampers not only the recognition of atopy in persons without manifest symptoms, but even the diagnostic classifi-cation of overt disease: It may not be possible to diagnose a condition as atopic when considering only its immediate symptomatology; this holds true particularly for the diagnosis of atopic eczema. Thus, in order to establish the presence of an atopic disposition or of an atopic disease, it is necessary to look for features known to be characteristically related to atopy.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Aizawa H, Tagami H (1989) Inability to produce white dermographism in the early stage of infantile eczema. Pediatr Dermatol 6: 6–9
Anderson WA, Elam MD, Clark Lambert W (1984) Keratosis punctata and atopy. Report of 31 cases with a prospective study of prevalence. Arch Dermatol 120: 884–890
Bieber K, Przybilla B, Ring J, Moosburner M (1989) Polymorphous light eruption (PLE): relationship to atopy and skin reactivity to sequels of mast cell activation ( Abstr ). Arch Dermatol Res 281: 124
Blaylock WK (1976) Atopic dermatitis: diagnosis and pathobiology. J Allergy Clin Immunol 57: 62–79
Borelli S, Schnyder UW (1962) Neurodermitis constitutionalis sive atopica. II. Ätiologie, Pathophysiologie, Pathogenese, Therapie. In: Miescher G, Storck H (eds) Entzündliche Dermatosen I. Springer, Berlin Göttingen Heidelberg, pp 254–319 (Handbuch der Haut-und Geschlechtskrankheiten, vol 2/1)
Braun-Falco O, Plewig G, Wolff HH (1984) Dermatologie und Venerologie. Springer, Berlin Heidelberg New York
Bresolin D, Shapiro GG, Shapiro PA, Dassel SW, Furukawa CT, Pierson WE, Chapko M, Warren Bierman C (1984) Facial characteristics of children who breathe through the mouth. Pediatrics 73: 622–625
Champion RH, Parish WE (1986) Atopic dermatitis. In: Rook A, Wilkinson DS, Ebling FJG, Champion RH, Burton JL (eds) Textbook of dermatology, 4th edn. Blackwell, Oxford, pp 419–434
Cusumano D, Berman B, Bershad S (1983) Dermatoglyphic patterns in patients with atopic dermatitis. J Am Acad Dermatol 8: 207–210
Diepgen TL, Fartasch M, Hornstein OP (1989) with atopic dermatitis and in the general population. Acta Derm Venereol [Suppl] (Stockh) 144: 50–54 34.
Ebbecke U (1917) Die lokale vasomotorische Reaktion (LVR) der Haut und der inneren Organe. Arch Gesamte Physiol 169: 1–81 35.
Fartasch M, Haneke E, Anton-Lamprecht I (1987) Ultra-structural study of the occurrence of autosomal dominant 36. ichthyosis vulgaris in atopic eczema. Arch Dermatol Res 279: 270–272 37.
Fartasch M, Diepgen TL, Hornstein OP (1989) Atopic dermatitis–ichthyosis vulgaris–hyperlinear palms–an 38. ultrastructural study. Dermatologica 178: 202–205
Finlay AY, Nicholls S, King CS, Marks R (1980) The “dry” 39. non-eczematous skin associated with atopic eczema. Br J Dermatol 102: 249–256
Grosshans E, Woehl M (1982) Troubles vasomoteurs, 40. sudoraux et sébacés de l’éczéma constitutionnel. Ann. Dermatol Venereol 109: 151–162 41.
Hanifin JM (1988) Atopic dermatitis. In: Middleton E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW (eds) Allergy. Principles and practice, 3rd edn. Mosby, St Louis, pp 1403–1428 42.
Hanifin JM, Lobitz WC (1977) Newer concepts of atopic dermatitis. Arch Dermatol 113: 663–670
Hanifin JM, Rajka G (1980) Diagnostic features of atopic dermatitis. Acta DermVenereol [Suppl] (Stockh) 92: 44–47
Hellerström S, Rajka G (1967) Clinical aspects of atopic 43. dermatitis. Acta Derm Venereol (Stockh) 47: 75–82
Herzberg J (1973) Wenig bekannte Formen der Neurodermitis. Hautarzt 24: 47–51 44.
Hirth L, Schöpf E, Benkmann HG, Goedde H W (1971) Untersuchungen der Hautfurchen bei Patienten mit 45. endogenem Ekzem mit einem Beitrag zur Technik der Daktyloskopie. Anthropol Anz 33: 26–38 46.
Holzegel K (1977) Unterlidfalte beim endogenen Ekzem. Hautarzt 28: 45 47.
Hßyer H, Agdal N, Munkvad M (1982) Palmar hyper-linearity in atopic dermatitis. Acta Derm Venereol (Stockh) 48. 62: 346–348
Ingram JT (1955) Besnier’s prurigo: an ectodermal defect. Br J Dermatol 67: 43–49 49.
Jones SK, English JSC, Forsyth A, MacKie RM (1987) Juvenile plantar dermatosis–an 8-year follow-up of 102 patients. Clin Exp Dermatol 12: 5–7
Kang K, Tian R (1987) Atopic dermatitis. An evaluation 50. of clinical and laboratory findings. Int J Dermatol 26: 27–32
Keining E, Braun-Falco 0 (1969) Dermatologie und Venerologie. Lehmanns, Munich 51.
Kierland RR (1955) Certain stigmata associated with atopic 52. dermatitis. In: Baer RL (ed) Atopic dermatitis. Lippincott, Philadelphia, pp 43–55 53.
Korting GW (1954) Zur Pathogenese des endogenen Ekzems. Thieme, Stuttgart
Korting GW (1959) Das endogene Ekzem. In: Gottron HA, Schönfeld W (eds) Dermatologie und Venerologie, vol 54. 3/1. Thieme, Stuttgart, pp 549–593
Leung DYM, Rhodes AR, Geha RS (1987) Atopic 55. dermatitis. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds) Dermatology in general 56. medicine, 3rd edn. McGraw-Hill, NewYork, pp 1385–1408
Leutgeb C, Bandmann HJ, Breit R (1972) Handlinien-muster, Ichthyosis vulgaris und Dermatitis atopica. Arch 57. Dermatol Forsch 244: 354–356
Lobitz WC, Dobson RL (1956) Physical and physiological clues for diagnosing eczema. JAMA 161: 1226–1229
Marks MB (1963) Significance of discoloration in the lower orbitopalpebral grooves in allergic children (allergic shiners). Ann Allergy 21: 26–32
Marks MB (1966) Allergic shiners. Dark circles under the eyes in children. Clin Pediatr 5: 655–658
Marks MB (1967) Physical signs of allergy of the respiratory tract in children. Ann Allergy 25: 310–317
Marks MB (1973) Unusual signs of respiratory tract allergy. Ann Allergy 31: 611–617
Marks R, Simons MJ (1979) Geographic tongue–a manifestation of atopy. Br J Dermatol 101: 159–162
Meenan FOC (1980) The significance of Morgan’s fold in children with atopic dermatitis. Acta Derm Venereol [Suppl] (Stockh) 92: 42–43
Meenan FOC (1981) Further observations of the DennieMorgan fold. Ir J Med Sci 150: 89–92
Meltzer Eo, Schatz M, Zeiger RS (1988) Allergic and nonallergic rhinitis. In: Middleton E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW (eds) Allergy. Principles and practice, 3rd edn. Mosby, St Louis, pp 1253–1289
Mevorah B, Marazzi A, Frenk E (1985) The prevalence of accentuated palmoplantar markings and keratosis pilaris in atopic dermatitis, autosomal dominant ichthyosis and control dermatological patients. Br J Dermatol 112: 679–685
Mevorah B, Frenk E, Witlisbach V, Carrel CF (1988) Minor clinical features of atopic dermatitis. Evaluation of their diagnostic significance. Dermatologica 177: 360–364
Morgan DB (1948) A suggestive sign of allergy. Arch Dermatol 57: 10–50
Myers WA (1960) the “nasal crease”. A physical sign of allergic rhinitis. JAMA 174: 1204–1206
Norins AL (1971) Atopic dermatitis. Pediatr Clin North Am 18: 801–838
Piérard GE (1989) What do you mean by dry skin? Dermatologica 179: 1–2
Podmore P, Burrows D, Eedy DJ, Stanford CF (1986) Seborrhoeic eczema–a disease entity or a clinical variant of atopic eczema? Br J Dermatol 115: 341–350
Przybilla B, Enders F, Ring J, Winklmann H (1991) Stigmata of atopic constitution in patients with atopic eczema or atopic respiratory disease. Acta Denn Venereol (Stockh) (in press)
Rajka G (1960) Prurigo Besnier (atopic dermatitis) with special reference to the role of allergic factors. I. The influence of atopic hereditary factors. Acta Denn Venereol (Stockh) 40: 285–306
Rajka G (1975) Atopic dermatitis. Saunders, London
Rajka G (1989) Essential aspects of atopic dermatitis. Springer, Berlin Heidelberg New York
Reed WB, Kierland RR, Code CF (1958) Vascular reactions in chronically inflamed skin. I. Mechanical stimuli to the skin; inhibition of white dermographism. Arch Dermatol 77: 91–96
Ring J (1988) Angewandte Allergologie. MMV-Medizin, Munich
Rost GA (1929) Allergische Disposition and Status exsudativus. Klin Wochenschr 8: 2009–2013
Rost GA, Marchionini A (1932) Asthma-Ekzem, Asthma-Prurigo and Neurodermitis als allergische Hautkrankheiten. Würzburger Abh Gesamtgeb Med 27: 337–400
Schaumann B, Alter M (1976) Dermatoglyphics in medical disorders. Springer, Berlin Heidelberg New York
Schnyder UW, Borelli S (1962) Neurodermitis constitutionalis sive atopica. I. Nomenklatur, klinische Symptomatologie. In: Miescher G, Storck H (eds) Entzündliche Dermatosen I. Springer, Berlin Göttingen Heidelberg (Handbuch der Haut-und Geschlechtskrankheiten, vol 2/1)
Schönberger A, Langenstein B, Heyer G, Hornstein OP (1988) Quantifizierte Bestimmung des Dermographismus bei Patienten mit atopischem Ekzem. Hautarzt 39: 72–76
Smith DA (1984) Hyperlinear palms in atopic dermatitis: a manifestation of ichthyosis vulgaris? Cutis 34: 49–51
Solomon LM (1985) Atopic dermatitis. In: Moschella SL, Hurley HJ (eds) Dermatology, 2nd edn. Saunders, Philadelphia, pp 334–353
Svensson A, Edman B, Möller H (1985) A diagnostic tool for atopic dermatitis based on clinical criteria. Acta Derm Venereol [Supplj (Stockh) 114: 33–40
Tillner I (1956) Über zwei Merkmale der Handfurchung und ihre Anwendbarkeit in der erbbiologischen Vaterschaftsbegutachtung. Anthropol Anz 20: 79–94
Toda KI, Okamoto H, Horio T (1986) Lichen striatus. Int J Dermatol 25: 584–585
Uehara M (1981) Infraorbital fold in atopic dermatitis. Arch Dermatol 117: 627–629
Uehara M (1985) Clinical and histological features of dry skin in atopic dermatitis. Acta Derm Venereol (Stockh) 114: 82–86
Uehara M, Hayashi S (1981) Hyperlinear palms. Association with ichthyosis and atopic dermatitis. Arch Dermatol 117: 490–491
Uehara M, Miyauchi H (1984) The morphologic characteristics of dry skin in atopic dermatitis. Arch Dermatol 120: 1186–1190
Uehara M, Ofuji S (1977) Abnormal vascular reactions in atopic dermatitis. Arch Dermatol 113: 627–629
Urbach E (1935) Klinik und Therapie der allergischen Krankheiten. Maudrich, Vienna
Werner Linde Y (1989) “Dry” skin in atopic dermatitis. I. A clinical study. Acta Derm Venereol (Stockh) 69: 311–314
Werner Linde Y, Bengtsson A, Lodén M (1989) “Dry” skin in atopic dermatitis. II. A surface profilometry study. Acta Derm Venereol (Stockh) 69: 315–319
Whitfield A (1938) On the white reaction (white line) in dermatology. Br J Dermatol 50: 71–82
Wong RC, Fairley JA, Ellis CN (1984) Dermographism: a review. J Am Acad Dermatol 11: 643–652
Wüthrich B, Schnyder UW (1981) Eine wenig bekannte Ausdrucksform der Neurodermitis atopica im Kindesalter: Das Patchy pityriasiform lichenoid eczema (“KitamuraTakahashi-Sasagawa”). Aktuel Dermatol 7: 85–87
Yoshida K, Mizuno N, Tada T (1974) Serum IgE level and white dermographism in atopic dermatitis, atopic skin, and infantile eczema. J Dermatol 1: 152–156
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Przybilla, B. (1991). Stigmata of the Atopic Constitution. In: Ruzicka, T., Ring, J., Przybilla, B. (eds) Handbook of Atopic Eczema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02671-7_5
Download citation
DOI: https://doi.org/10.1007/978-3-662-02671-7_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-02673-1
Online ISBN: 978-3-662-02671-7
eBook Packages: Springer Book Archive