Skip to main content

Stigmata of the Atopic Constitution

  • Chapter

Abstract

Atopy is a constitutional state defined by the genetically determined disposition to develop atopic eczema, allergic rhinoconjunctivitis, and/or allergic asthma. Up to now, no definite marker has been available which would allow one to decide with certainty whether atopy is present or absent in a given individual. This hampers not only the recognition of atopy in persons without manifest symptoms, but even the diagnostic classifi-cation of overt disease: It may not be possible to diagnose a condition as atopic when considering only its immediate symptomatology; this holds true particularly for the diagnosis of atopic eczema. Thus, in order to establish the presence of an atopic disposition or of an atopic disease, it is necessary to look for features known to be characteristically related to atopy.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aizawa H, Tagami H (1989) Inability to produce white dermographism in the early stage of infantile eczema. Pediatr Dermatol 6: 6–9

    Article  PubMed  CAS  Google Scholar 

  2. Anderson WA, Elam MD, Clark Lambert W (1984) Keratosis punctata and atopy. Report of 31 cases with a prospective study of prevalence. Arch Dermatol 120: 884–890

    Article  PubMed  CAS  Google Scholar 

  3. Bieber K, Przybilla B, Ring J, Moosburner M (1989) Polymorphous light eruption (PLE): relationship to atopy and skin reactivity to sequels of mast cell activation ( Abstr ). Arch Dermatol Res 281: 124

    Google Scholar 

  4. Blaylock WK (1976) Atopic dermatitis: diagnosis and pathobiology. J Allergy Clin Immunol 57: 62–79

    Article  PubMed  CAS  Google Scholar 

  5. Borelli S, Schnyder UW (1962) Neurodermitis constitutionalis sive atopica. II. Ätiologie, Pathophysiologie, Pathogenese, Therapie. In: Miescher G, Storck H (eds) Entzündliche Dermatosen I. Springer, Berlin Göttingen Heidelberg, pp 254–319 (Handbuch der Haut-und Geschlechtskrankheiten, vol 2/1)

    Google Scholar 

  6. Braun-Falco O, Plewig G, Wolff HH (1984) Dermatologie und Venerologie. Springer, Berlin Heidelberg New York

    Google Scholar 

  7. Bresolin D, Shapiro GG, Shapiro PA, Dassel SW, Furukawa CT, Pierson WE, Chapko M, Warren Bierman C (1984) Facial characteristics of children who breathe through the mouth. Pediatrics 73: 622–625

    PubMed  CAS  Google Scholar 

  8. Champion RH, Parish WE (1986) Atopic dermatitis. In: Rook A, Wilkinson DS, Ebling FJG, Champion RH, Burton JL (eds) Textbook of dermatology, 4th edn. Blackwell, Oxford, pp 419–434

    Google Scholar 

  9. Cusumano D, Berman B, Bershad S (1983) Dermatoglyphic patterns in patients with atopic dermatitis. J Am Acad Dermatol 8: 207–210

    Article  PubMed  CAS  Google Scholar 

  10. Diepgen TL, Fartasch M, Hornstein OP (1989) with atopic dermatitis and in the general population. Acta Derm Venereol [Suppl] (Stockh) 144: 50–54 34.

    Google Scholar 

  11. Ebbecke U (1917) Die lokale vasomotorische Reaktion (LVR) der Haut und der inneren Organe. Arch Gesamte Physiol 169: 1–81 35.

    Google Scholar 

  12. Fartasch M, Haneke E, Anton-Lamprecht I (1987) Ultra-structural study of the occurrence of autosomal dominant 36. ichthyosis vulgaris in atopic eczema. Arch Dermatol Res 279: 270–272 37.

    Google Scholar 

  13. Fartasch M, Diepgen TL, Hornstein OP (1989) Atopic dermatitis–ichthyosis vulgaris–hyperlinear palms–an 38. ultrastructural study. Dermatologica 178: 202–205

    Article  PubMed  CAS  Google Scholar 

  14. Finlay AY, Nicholls S, King CS, Marks R (1980) The “dry” 39. non-eczematous skin associated with atopic eczema. Br J Dermatol 102: 249–256

    Article  Google Scholar 

  15. Grosshans E, Woehl M (1982) Troubles vasomoteurs, 40. sudoraux et sébacés de l’éczéma constitutionnel. Ann. Dermatol Venereol 109: 151–162 41.

    Google Scholar 

  16. Hanifin JM (1988) Atopic dermatitis. In: Middleton E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW (eds) Allergy. Principles and practice, 3rd edn. Mosby, St Louis, pp 1403–1428 42.

    Google Scholar 

  17. Hanifin JM, Lobitz WC (1977) Newer concepts of atopic dermatitis. Arch Dermatol 113: 663–670

    Article  PubMed  CAS  Google Scholar 

  18. Hanifin JM, Rajka G (1980) Diagnostic features of atopic dermatitis. Acta DermVenereol [Suppl] (Stockh) 92: 44–47

    Google Scholar 

  19. Hellerström S, Rajka G (1967) Clinical aspects of atopic 43. dermatitis. Acta Derm Venereol (Stockh) 47: 75–82

    Google Scholar 

  20. Herzberg J (1973) Wenig bekannte Formen der Neurodermitis. Hautarzt 24: 47–51 44.

    Google Scholar 

  21. Hirth L, Schöpf E, Benkmann HG, Goedde H W (1971) Untersuchungen der Hautfurchen bei Patienten mit 45. endogenem Ekzem mit einem Beitrag zur Technik der Daktyloskopie. Anthropol Anz 33: 26–38 46.

    Google Scholar 

  22. Holzegel K (1977) Unterlidfalte beim endogenen Ekzem. Hautarzt 28: 45 47.

    Google Scholar 

  23. Hßyer H, Agdal N, Munkvad M (1982) Palmar hyper-linearity in atopic dermatitis. Acta Derm Venereol (Stockh) 48. 62: 346–348

    Google Scholar 

  24. Ingram JT (1955) Besnier’s prurigo: an ectodermal defect. Br J Dermatol 67: 43–49 49.

    Google Scholar 

  25. Jones SK, English JSC, Forsyth A, MacKie RM (1987) Juvenile plantar dermatosis–an 8-year follow-up of 102 patients. Clin Exp Dermatol 12: 5–7

    Article  PubMed  CAS  Google Scholar 

  26. Kang K, Tian R (1987) Atopic dermatitis. An evaluation 50. of clinical and laboratory findings. Int J Dermatol 26: 27–32

    Article  PubMed  CAS  Google Scholar 

  27. Keining E, Braun-Falco 0 (1969) Dermatologie und Venerologie. Lehmanns, Munich 51.

    Google Scholar 

  28. Kierland RR (1955) Certain stigmata associated with atopic 52. dermatitis. In: Baer RL (ed) Atopic dermatitis. Lippincott, Philadelphia, pp 43–55 53.

    Google Scholar 

  29. Korting GW (1954) Zur Pathogenese des endogenen Ekzems. Thieme, Stuttgart

    Google Scholar 

  30. Korting GW (1959) Das endogene Ekzem. In: Gottron HA, Schönfeld W (eds) Dermatologie und Venerologie, vol 54. 3/1. Thieme, Stuttgart, pp 549–593

    Google Scholar 

  31. Leung DYM, Rhodes AR, Geha RS (1987) Atopic 55. dermatitis. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds) Dermatology in general 56. medicine, 3rd edn. McGraw-Hill, NewYork, pp 1385–1408

    Google Scholar 

  32. Leutgeb C, Bandmann HJ, Breit R (1972) Handlinien-muster, Ichthyosis vulgaris und Dermatitis atopica. Arch 57. Dermatol Forsch 244: 354–356

    CAS  Google Scholar 

  33. Lobitz WC, Dobson RL (1956) Physical and physiological clues for diagnosing eczema. JAMA 161: 1226–1229

    Article  Google Scholar 

  34. Marks MB (1963) Significance of discoloration in the lower orbitopalpebral grooves in allergic children (allergic shiners). Ann Allergy 21: 26–32

    Google Scholar 

  35. Marks MB (1966) Allergic shiners. Dark circles under the eyes in children. Clin Pediatr 5: 655–658

    Article  CAS  Google Scholar 

  36. Marks MB (1967) Physical signs of allergy of the respiratory tract in children. Ann Allergy 25: 310–317

    PubMed  CAS  Google Scholar 

  37. Marks MB (1973) Unusual signs of respiratory tract allergy. Ann Allergy 31: 611–617

    PubMed  CAS  Google Scholar 

  38. Marks R, Simons MJ (1979) Geographic tongue–a manifestation of atopy. Br J Dermatol 101: 159–162

    Article  PubMed  CAS  Google Scholar 

  39. Meenan FOC (1980) The significance of Morgan’s fold in children with atopic dermatitis. Acta Derm Venereol [Suppl] (Stockh) 92: 42–43

    Google Scholar 

  40. Meenan FOC (1981) Further observations of the DennieMorgan fold. Ir J Med Sci 150: 89–92

    Article  PubMed  CAS  Google Scholar 

  41. Meltzer Eo, Schatz M, Zeiger RS (1988) Allergic and nonallergic rhinitis. In: Middleton E, Reed CE, Ellis EF, Adkinson NF, Yunginger JW (eds) Allergy. Principles and practice, 3rd edn. Mosby, St Louis, pp 1253–1289

    Google Scholar 

  42. Mevorah B, Marazzi A, Frenk E (1985) The prevalence of accentuated palmoplantar markings and keratosis pilaris in atopic dermatitis, autosomal dominant ichthyosis and control dermatological patients. Br J Dermatol 112: 679–685

    Article  PubMed  CAS  Google Scholar 

  43. Mevorah B, Frenk E, Witlisbach V, Carrel CF (1988) Minor clinical features of atopic dermatitis. Evaluation of their diagnostic significance. Dermatologica 177: 360–364

    Google Scholar 

  44. Morgan DB (1948) A suggestive sign of allergy. Arch Dermatol 57: 10–50

    Article  Google Scholar 

  45. Myers WA (1960) the “nasal crease”. A physical sign of allergic rhinitis. JAMA 174: 1204–1206

    Google Scholar 

  46. Norins AL (1971) Atopic dermatitis. Pediatr Clin North Am 18: 801–838

    PubMed  CAS  Google Scholar 

  47. Piérard GE (1989) What do you mean by dry skin? Dermatologica 179: 1–2

    PubMed  Google Scholar 

  48. Podmore P, Burrows D, Eedy DJ, Stanford CF (1986) Seborrhoeic eczema–a disease entity or a clinical variant of atopic eczema? Br J Dermatol 115: 341–350

    Article  PubMed  CAS  Google Scholar 

  49. Przybilla B, Enders F, Ring J, Winklmann H (1991) Stigmata of atopic constitution in patients with atopic eczema or atopic respiratory disease. Acta Denn Venereol (Stockh) (in press)

    Google Scholar 

  50. Rajka G (1960) Prurigo Besnier (atopic dermatitis) with special reference to the role of allergic factors. I. The influence of atopic hereditary factors. Acta Denn Venereol (Stockh) 40: 285–306

    CAS  Google Scholar 

  51. Rajka G (1975) Atopic dermatitis. Saunders, London

    Google Scholar 

  52. Rajka G (1989) Essential aspects of atopic dermatitis. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  53. Reed WB, Kierland RR, Code CF (1958) Vascular reactions in chronically inflamed skin. I. Mechanical stimuli to the skin; inhibition of white dermographism. Arch Dermatol 77: 91–96

    Google Scholar 

  54. Ring J (1988) Angewandte Allergologie. MMV-Medizin, Munich

    Google Scholar 

  55. Rost GA (1929) Allergische Disposition and Status exsudativus. Klin Wochenschr 8: 2009–2013

    Article  Google Scholar 

  56. Rost GA, Marchionini A (1932) Asthma-Ekzem, Asthma-Prurigo and Neurodermitis als allergische Hautkrankheiten. Würzburger Abh Gesamtgeb Med 27: 337–400

    Google Scholar 

  57. Schaumann B, Alter M (1976) Dermatoglyphics in medical disorders. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  58. Schnyder UW, Borelli S (1962) Neurodermitis constitutionalis sive atopica. I. Nomenklatur, klinische Symptomatologie. In: Miescher G, Storck H (eds) Entzündliche Dermatosen I. Springer, Berlin Göttingen Heidelberg (Handbuch der Haut-und Geschlechtskrankheiten, vol 2/1)

    Google Scholar 

  59. Schönberger A, Langenstein B, Heyer G, Hornstein OP (1988) Quantifizierte Bestimmung des Dermographismus bei Patienten mit atopischem Ekzem. Hautarzt 39: 72–76

    PubMed  Google Scholar 

  60. Smith DA (1984) Hyperlinear palms in atopic dermatitis: a manifestation of ichthyosis vulgaris? Cutis 34: 49–51

    PubMed  CAS  Google Scholar 

  61. Solomon LM (1985) Atopic dermatitis. In: Moschella SL, Hurley HJ (eds) Dermatology, 2nd edn. Saunders, Philadelphia, pp 334–353

    Google Scholar 

  62. Svensson A, Edman B, Möller H (1985) A diagnostic tool for atopic dermatitis based on clinical criteria. Acta Derm Venereol [Supplj (Stockh) 114: 33–40

    CAS  Google Scholar 

  63. Tillner I (1956) Über zwei Merkmale der Handfurchung und ihre Anwendbarkeit in der erbbiologischen Vaterschaftsbegutachtung. Anthropol Anz 20: 79–94

    Google Scholar 

  64. Toda KI, Okamoto H, Horio T (1986) Lichen striatus. Int J Dermatol 25: 584–585

    Article  PubMed  CAS  Google Scholar 

  65. Uehara M (1981) Infraorbital fold in atopic dermatitis. Arch Dermatol 117: 627–629

    Article  PubMed  CAS  Google Scholar 

  66. Uehara M (1985) Clinical and histological features of dry skin in atopic dermatitis. Acta Derm Venereol (Stockh) 114: 82–86

    CAS  Google Scholar 

  67. Uehara M, Hayashi S (1981) Hyperlinear palms. Association with ichthyosis and atopic dermatitis. Arch Dermatol 117: 490–491

    Google Scholar 

  68. Uehara M, Miyauchi H (1984) The morphologic characteristics of dry skin in atopic dermatitis. Arch Dermatol 120: 1186–1190

    Article  PubMed  CAS  Google Scholar 

  69. Uehara M, Ofuji S (1977) Abnormal vascular reactions in atopic dermatitis. Arch Dermatol 113: 627–629

    Article  PubMed  CAS  Google Scholar 

  70. Urbach E (1935) Klinik und Therapie der allergischen Krankheiten. Maudrich, Vienna

    Google Scholar 

  71. Werner Linde Y (1989) “Dry” skin in atopic dermatitis. I. A clinical study. Acta Derm Venereol (Stockh) 69: 311–314

    Google Scholar 

  72. Werner Linde Y, Bengtsson A, Lodén M (1989) “Dry” skin in atopic dermatitis. II. A surface profilometry study. Acta Derm Venereol (Stockh) 69: 315–319

    Google Scholar 

  73. Whitfield A (1938) On the white reaction (white line) in dermatology. Br J Dermatol 50: 71–82

    Article  Google Scholar 

  74. Wong RC, Fairley JA, Ellis CN (1984) Dermographism: a review. J Am Acad Dermatol 11: 643–652

    Article  PubMed  CAS  Google Scholar 

  75. Wüthrich B, Schnyder UW (1981) Eine wenig bekannte Ausdrucksform der Neurodermitis atopica im Kindesalter: Das Patchy pityriasiform lichenoid eczema (“KitamuraTakahashi-Sasagawa”). Aktuel Dermatol 7: 85–87

    Google Scholar 

  76. Yoshida K, Mizuno N, Tada T (1974) Serum IgE level and white dermographism in atopic dermatitis, atopic skin, and infantile eczema. J Dermatol 1: 152–156

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Przybilla, B. (1991). Stigmata of the Atopic Constitution. In: Ruzicka, T., Ring, J., Przybilla, B. (eds) Handbook of Atopic Eczema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02671-7_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-02671-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-02673-1

  • Online ISBN: 978-3-662-02671-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics