Pelizaeus-Merzbacher Disease

  • Jacob Valk
  • Marjo S. van der Knaap


Pelizaeus-Merzbacher disease (PMD) is a rare neurological disorder affecting the myelination of the CNS in children. The disease can be subdivided into three types: the classical type, the connatal type, and the transitional form.


White Matter Myelin Sheath Subcortical White Matter Transitional Form Centrum Semiovale 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Jacob Valk
    • 1
  • Marjo S. van der Knaap
    • 2
  1. 1.Department of Diagnostic Radiology and NeuroradiologyFree University HospitalAmsterdamThe Netherlands
  2. 2.Department of Child NeurologyAcademic HospitalUtrechtThe Netherlands

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