Abstract
Aims of pharmacokinetic computations are identified for an evaluation strategy useful to define criteria for software selection and software development.
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References
Beal, S.L. & Sheiner, L.B. (1992). NONMEM User’s Guide. NONMEM Project Group, UCSF San Francisco.
Brier, M.E. & Aronoff, G.R. (1996). Application of artificial neural networks to clinical pharmacology. Int. J. Clinical Pharmacology and Therapeutics, 34, 510–514.
Carrol, R.J. & Ruppert, D. (1988). Transformation and Weighting in Regression. New York: Chapman & Hall.
Edler, L. & Berger, J. (1984). FITTEN — An APL Workspace for nonlinear regression. APL Quote Quad, 13, 96–104.
Edler (1994). Computational aspects in uncertainty analyses of physiologicallybased pharmacokinetic models. In: COMPSTAT94 Proceedings in Computational Statistics, 539–544. Heidelberg: Physica-Verlag.
Edler, L. (1998). 6/12/5000 Pharmakokinetik. In: Verfahrensbibliothek. Versuchsplanung und auswertung (ed. Rasch, D., Herrendörfer, G., Bock, J., Victor, N. & Guiard, V), 629 – 638. Muenchen: R. Oldenburg.
Gex-Fabry, M. & Balant, L.P. (1994). Considerations on data analysis using computer methods and currently available software for personal computers. In: Handbook of Experimental Pharmacology (ed. Welling P. and H. Balant). Vol 110, Pharmacokinetics of Drugs, 507–527. New York: Springer.
Gibaldi, M. & Perrier, D. (1982): Pharmacokinetics. (2nd Ed and expanded). Marcel Dekker: New York.
Jackson, R. C. (1996). Computer Techniques in Preclinical and Clinical Drug Development. CRC Press: Boca Raton.
Meibohm, D. & Derendorf, H. (1997). Basic concepts of pharmacokinetic / pharmacodynamik (PK/PD) modelling. Int. J. of Clinical Pharmacology and Therapeutics, 35, 401–413.
Metzler, C.M. (1969). A user’s manual for NONLIN. The Upjohn Co. Techn. Rep. 7292/69/7292/005. Kalama 700. Mich.
Wakefield, J. & Racine-Poon, A. (1994): An application of Bayesian population pharmacokinetic/pharmacodynamic models to dose recommendation. Statistics in Medicine, 14, 971–986.
Yuh, L., Beal, S., Davidian, M., Harrison, F., Hester, A., Kowalski, K., Vonesh, E. & Wolfinger, R. (1994): Population pharmacokinetic/pharmacodynamic methodology and applications: A bibliography. Biometrics, 50, 566–575.
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Edler, L. (1998). Computational Statistics for Pharmacokinetic Data Analysis. In: Payne, R., Green, P. (eds) COMPSTAT. Physica, Heidelberg. https://doi.org/10.1007/978-3-662-01131-7_35
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DOI: https://doi.org/10.1007/978-3-662-01131-7_35
Publisher Name: Physica, Heidelberg
Print ISBN: 978-3-7908-1131-5
Online ISBN: 978-3-662-01131-7
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