Abstract
Simple and reliable micromethods for the detection of metabolic changes are very much needed in the medical research laboratory. These methods should be rapid and capable of being carried out in series. Shortly after the first successful separation of amino acid mixtures by paper chromatography, this technique was used extensively in medical laboratories for analyzing such substances. Electrophoresis (ionophoresis), on various layers1, was subsequently introduced as a valuable diagnostic procedure for separating mixtures of ionic compounds. In particular, it was rapidly adopted as a diagnostic method for analyzing proteins. The mixtures are applied as bands; after separation, they can be evaluated quantitatively with the aid of various self-recording photoelectric instruments.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliography to Chapter G. TLC in Clinical Diagnosis and Pharmacology
Demole, E.: J. Chromatog. 1, 24 (1958).
Dibbern, H. W., and H. Picner: Arzneimittel-Forsch. 11, 317 (1961).
Martin, H.: Private communication.
Reimahn-Hunziker, R., and W. Wild: Munch. med. Wschr. 103, 1264 (1961).
Waldi, D., F. Munter and E. Wolpert: Med. exp. (Basel) 3, 45 (1960).
Waldi, D., F. Munter and E. Wolpert: Klin. Wschr. 40, 827 (1962).
Waldi, D., F. Munter and E. Wolpert: Arch. Pharm. 295 /32, 125 (1962).
Wagner, H.: Mitt. Gebiete Lebensm. and Hyg. 51, 416 (1960).
Williams, J. A., A. Sharma, L. J. Morris and R. Holman: PTOC. SOC. Exptl. Biol. Med. 105, 192 (1960).
Some recent noteworthy articles
Funcx, F. W., and L. Zicha: Med. Exp. (Basel) 7, 1 (1962): Metabolites from prednisolone and derivatives.
Jatzkewitz, H., and K. Sandhoff: Biochim. Biophys. Acta 70, 354 (1963): Tay-Sachs disease.
Pataki, G., and M. Keller: Z klin. Chem. (Berlin) 1, 157 (1963): Estimation of amino acids in blood.
Schmid, E., L. Zicha, J. Krauthelm and J. Blumberg: Med. Exp. (Basel) 7, 8 (1962): Biogenic amines and their metabolites.
Waldi, D.: Ärztl. Labor. 9, 221 (1963): Progesterone in serum.
Walz, D., A. R Fahmy, G. Pataki, A. Niederwieser and M. Brenner: Experientia 19, 213 (1963): Amino acids in urine.
Zöllner, N.: Z. kün Chem. (Berlin) 1, 18 (1963): Plasma lipids.
Zöllner, N., and G. Wolfram: Klin Wschr. 40, 1101 (1962): TLC of plasma lipids.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1965 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Waldi, D. (1965). Thin-Layer Chromatography in Clinical Diagnosis and Pharmacology. In: Stahl, E. (eds) Thin-Layer Chromatography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-01031-0_16
Download citation
DOI: https://doi.org/10.1007/978-3-662-01031-0_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-01033-4
Online ISBN: 978-3-662-01031-0
eBook Packages: Springer Book Archive