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Parathyroids, Hypertension, and Vascular Reactivity

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Cellular Aspects of Hypertension

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Abstract

Bone, kidney, and intestine are the main targets for parathyroid hormone (PTH) [22]. Nevertheless, cardiovascular effects with vasodilatation and hypotension have been described, initially with parathyroid extracts, then confirmed with the synthetic hormone (bovine PTH1–84) and fragments (PTH1–34, rat, bovine, human sequences). Only very recently, high affinity binding sites for PTH fragments have been described on rabbit renal microvessels [52].

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Authors and Affiliations

  1. Faculté de Pharmacie, Université Louis Pasteur, Strasbourg, Laboratoire de Pharmacologie Cellulaire et Moléculaire CNRS URA600, 74 Route du Rhin, BP 24, F-67400, Illkirch-Graffenstaden, France

    A. Gairard, R. Schleiffer, F. Pernot, C. Bergmann & B. van Overloop

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  1. A. Gairard
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  2. R. Schleiffer
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  3. F. Pernot
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  4. C. Bergmann
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  5. B. van Overloop
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  1. Istituto di Clinica Medica e Nefrologia, Facolta di Medicina e Chirurgia, Università degli Studi di Parma, Via A. Gramsci, 14, I-43100, Parma, Italy

    Giacomo Bruschi  & Alberico Borghetti  & 

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Gairard, A., Schleiffer, R., Pernot, F., Bergmann, C., van Overloop, B. (1991). Parathyroids, Hypertension, and Vascular Reactivity. In: Bruschi, G., Borghetti, A. (eds) Cellular Aspects of Hypertension. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00983-3_12

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