Zusammenfassung
In der Veterinärmedizin sind Gestagene überall dort anwendbar,
-
1.
wo ein absolutes oder relatives Gestagendefizit die gewünschte Fortpflanzungsfunktion in Frage stellt (Substitutionstherapie);
-
2.
wo ruhende, partiell insuffiziente oder unterschwellige Sexualfunktionen durch die positive Feedback-Wirkung kleiner Gestagendosen am hypothalamohypophysären Sexualzentrum stimuliert werden können;
-
3.
wo Impulsunterbrechungen, d. h. temporäre zentrale Ruhigstellung mit höher dosierten Gestagenen — durch negative Feedback-Wirkungen — entgleist gewesene Funktionskreise erfahrungsgemäß wieder einzuregeln vermögen. Dabei unterstützt die mit dem Abklingen der Gestagenwirkung wieder positiv werdende Feedback-Aktion das Wieder-Ingangkommen regelgerechter Fortpflanzungsfunktionen, wobei mit Hilfe des „Rebound-Phänomens“ höhere Leistungen der Fortpflanzungsfunktionen (sowohl germinativer wie neuroendokriner Art) erzielt werden können [56, 70].
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Jöchle, W. (1969). Die Anwendung der Gestagene in Veterinärmedizin und Zootechnik. In: Boschann, HW., et al. Die Gestagene. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 22 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00826-3_4
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