Abstract
Dreams of rejuvenation of the aging male through the agency of testicular essences dates back at least to Berthold (1849) who transplanted rooster testes into capons with salubrious effect. He was followed by Brown-Séquard who reported similar benefits from self-injection of aqueous (and therefore probably inert) extracts of dog and guinea pig testes (1889). By 1918 Stanley and Kelkar were implanting testes from a dead human into a living person. Working at San Quentin prison at a time when there were on the average three executions per year, “valuable material for this kind of work became available.” The eleven implants all became necrotic, but transiently produced (claims of) enhanced mood.
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Place, V.A., Atkinson, L., Prather, D.A., Trunnell, N., Yates, F.E. (1990). Transdermal testosterone replacement through genital skin. In: Nieschlag, E., Behre, H.M. (eds) Testosterone. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00814-0_9
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