Abstract
More than ten years ago Eigen (1971) started to develop a dynamical model of molecular self-organization which is based mainly on chemical kinetics and the presently known properties of biopolymers. Later on, this theoretical concept was extended (Eigen & Schuster, 1979,1982) and supported by experimental studies (Biebricher et al.,1981, 1982; Biebricher, 1983; for a popular review see Eigen et al.,1981). The model starts out from the simplest prerequisites: polynucleotides are present and activated monomers are available in sufficient amounts. Several principles of self-organization can be derived by straightforward analysis. We just enumerate them here.
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References
Biebricher, C.K. (1983). Darwinian selection of cules. Evolutionary Biology (ed. M.K.Hechet, Vol. 16, 1–52. New York: Plenum.
Biebricher, C.K., Diekmann, S & Luce, R. (1982). replicating RNA synthesized by Qß replicase. self-replication RNA mole- B.Wallace & G.T.Prance), Structural analysis of selfJ.Mol.Biol. 154, 629–648
Biebricher, C.K., Eigen, M. Luce, R. (1981). Product analysis of RNA generated de novo by Qß replicase. J.Mol.Biol., 390–396 and Kinetic analysis of template-instructed and de novo RNA synthesis by Qß replicase. J.Mol.Biol., 148, 391–410.
Cedergren, R.J., Sankoff, D., La Rue, B., Grosjean (1981). The evolving t-RNA molecule. CRC Critical Reviews in Biochemistry, 11, 35–104.
Eigen, M. (1971). Selforganization of matter and the evolution of biological macromolecules. Naturwissenschaften, 58, 465–526.
Eigen, M. & Schuster, P. (1979). The hypercycle - a principle of biological self-organization. Berlin: Springer.
Eigen, M. & Schuster, P. (1982). Stages of emerging life–five principles of early organization. J.Mol.Evol., 19, 47–61.
Eigen, M. & Winkler-Oswatitsch, R. (1981). Transfer-RNA: the early adaptor. Naturwissenschaften, 68, 217–228 and Transfer-RNA, an early gene? Naturwissenschaften, 68, 282–292.
Eigen, M., Gardiner, W., Schuster, P. & Winkler-Oswatitsch, R. (1981). The origin of genetic information. Scientific American, 244 (4) 88–118.
Eigen, M., McCaskill, J. & Schuster, P. (1984). in preparation.
Fox, S.W., Nakashima, T., Przybylski, A. & Syren, R.M. (1982).
The updated experimental protenoid model. Int.J.Quantum Chem.Quantum Biol.Symp., 8, 441–454.
Inoue, T. & Orgel L.E. (1983). A nonenzymatic RNA polymerase model. Science, 219, 859–862.
Lodish, H.F. & Rothman, J.E. (1979). The assembly of cell membranes. Scientific American, 240 (1) 38–53.
Maynard-Smith, J. (1983). Models of evolution. Proc.Roy.Soc.London B 219, 315–325.
Miele, E.A., Mills, D.R., & Kramer, F.R. (1983). Autocatalytic replication of a recombinant RNA. J.Mol.Biol., 171, 281–295.
Schuster, P. (1981). Prebiotic evolution. In Biochemical Evolution ed. H.Gutfreund, pp. 15–87. Cambridge, U.K.: Cambridge Univ. Press.
Schuster, P. & Sigmund, K. (1984). Random selection and the neutral theory–sources of stochasticity in replication. In Stochastic phenomena and chaotic behaviour in complex systems, ed. P. Schuster pp. 186–205. Berlin: Springer
Shepard, J.C.W. (1981). Periodic correlations in DNA sequences and evidence suggesting their evolutionary origin in a commaless genetic code.
Spiegelman, S. (1971). An approach to the experimental analysis of precellular evolution. Quarterly review of biophysics 4, 213–253
Swetina, J. & Schuster, P. (1982). Self-replication with errors. A model for polynucleotide replication. Biophysical Chemistry 16, 329–345.
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© 1985 International Institute for Applied Systems Analysis, Laxenburg/Austria
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Schuster, P. (1985). The Interface between Chemistry and Biology — Laws Determining Regularities in Early Evolution. In: Aubin, JP., Saari, D., Sigmund, K. (eds) Dynamics of Macrosystems. Lecture Notes in Economics and Mathematical Systems, vol 257. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00545-3_20
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DOI: https://doi.org/10.1007/978-3-662-00545-3_20
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