Abstract
The commonest form of malnutrition in the tropics is protein calorie malnutrition (P.C.M.) of childhood. The spectrum of clinical features associated with this type of malnutrition is characterised at one extreme by mar asmus which results from a gross deficiency of calories and, at the other extreme, by kwashiorkor which results from a primary deficiency of protein. Many variants are present within this spectrum depending on the ratio of deficiency of protein and calories and also on other factors such as the inorganic and vitamin content of the diet. In describing the aetiology of these conditions it will be necessary to refer to the more pure states, but it must be evident that in all cases the deficiencies involve to some extent both protein and calorie deficiency.
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References
Childhood Malnutrition
Adams, E. B., Scragg, J. N., Naidoo, B. T., Liljestrand, S. K., Cockram, V. I.: Observations on the aetiology and treatment of anaemia in kwashiorkor. Brit. med. J. 3, 451 (1967) .
Allen, D. M., Dean, R. F. A.: The anaemia of kwashiorkor in Uganda. Trans. roy. Soc. trop. Med. Hyg. 59, 326 (1965) .
Arroyave, G., Wilson, D.: Urinary excretion of creatinine of children under different nutritional conditions. Amer. J. clin. Nutr. 9, 170 (1961) .
Cook, G. C., Lee, F. D.: The jejunum after kwashiorkor. Lancet 1966 II, 1263.
Edington, G. M., Gilles, H. M.: Pathology in the tropics. London: Edward Arnold 1969.
Hutt, M. S. R.: Some aspects of liver disease in Ugandan Africans. Trans. roy. Soc. trop. Med. Hyg. 65, 273 (1971) .
Jelliffe, D. B.: The assessment of the nutritional status of the community (with special reference to field surveys in developing regions of the world) . Wld Hlth Org. Monogr. Ser. 53 (1966) .
Jelliffe, E. F., Jelliffe, D. B.: The arm circumference as a public health index of proteincalorie malnutrition of early childhood. J. trop. Pediat. 15 (Monogr. No. 8), 179 (1969) .
Morley, D. C.: Severe measles in the tropics. Brit. med. J. I, 297 (1969) .
Mugerwa, T.: The lymphoreticular system in kwashiorkor. J. Path. 105, 105 (1971a).
Mugerwa, J.: M.D.Thesis, University of East Africa (1971b).
Owor, R.: Pathological features of chronic pancreatic disease in Uganda. E. Afr. med. J. 47, 604 (1970).
Stanfield, J. P., Hutt, M. S. R., Tunnicliffe, R.: Intestinal biopsy in kwashiorkor. Lancet 1965 II, 519.
Templeton, A. C.: Generalised herpes simplex in malnourished children. J. clin. Path. 23, 24 (1970) .
Trowell, H. C., Davies, J. N. P., Dean, R. F. A.: Kwashiorkor. London: Edward Arnold 1954.
Vint, F. W.: Post-mortem findings in the natives of Kenya. E. Afr. med. J. 13, 332 (1937) .
Watts, T.: Thymus weights in malnourished children. J. trop. Pediat. 15, 155 (1969) .
Whitehead, R. G.: Rapid determination of some plasma aminoacids in sub-clinical kwashiorkor. Lancet 1964 I, 250.
Whitehead, R. G.: Hydroxyproline creatinine ratio as an index of nutritional status and rate of growth. Lancet 1965 II, 567.
Whitehead, R. G.: Biochemical tests for assessing subclinical nutritional deficiency. Clin. Pediat. 6, 516 (1968) .
Wld Hlth Org. Expert Committee on Medical Assessment of nutritional status. Techn. Rep. Ser. 258 (1963) .
Nutritional Siderosis
Banwell, J. G., Hutt, M. S. R., Leonard, P. J., Blackman, V., Connor, D. H., Marsden, P. D., Campbell, J.: Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa. Gut 8, 388 (1967) .
Bradlow, B. A., Dunn, J. A., Higginson, J.: The effect of cirrhosis on iron storage. Amer. J. Path. 39, 221 (1961) .
Charlton, R. W., Bothwell, T. H.: Hemochromatosis: dietary and genetic aspects. Progr. Hemat. 5, 298 (1966) .
Dodu, S. R. A.: Diabetes and haemosiderosis - haemochromatosis — in Ghana. Trans. roy. Soc. trop. Med. Hyg. 52, 425 (1958) .
Edington, G. M.: Nutritional siderosis in Ghana. Cent. Afr. J. Med. 5, 186 (1959) .
Gillman, J., Gillman, T.: Perspectives in human malnutrition. New York: Grune and Stratton 1951.
Gillman, T., Canham, P. A. S., Hathorn, M.: Experimental nutritional siderosis. Lancet 1958 II, 557.
Gillman, T., Hathorn, M., Canham, P. A. S.: Experimental dietary siderosis. Amer. J. Path 35, 349 (1959) .
Haddock, D. R.: Bantu siderosis in Tanzania. E. Afr. med. J. 42, 67 (1965).
Higginson, J., Gerritsen, T., Walker, A. R. P.: Siderosis in the Bantu of Southern Africa. Amer. J. Path. 29, 779 (1953) .
Hutt, M. S. R.: Some aspects of liver disease in Ugandan Africans. Trans. roy. Soc. trop. Med. Hyg. 65, 273 (1971) .
Lowenthal, M. N., Hamilton, P. J. S., Hutt, M. S. R., Wilks, N. E.: Big. spleen disease in Zambia. Cent. Afr. J. Med. 12, 99 (1966) .
Macdonald, R. A.: Primary hemochromatosis: inherited or acquired? Progr. Hemat. 5, 324 (1966) .
Owor, R.: M.D. Thesis, University of East Africa 1971.
Seftel, H. C., Isaacson, C., Bothwell, T. H.: The relationship between siderosis and diabetes in the Bantu. S. Afr. med. J. 25, 89 (1960) .
Wainwright, J.: Siderosis in the African. S. Afr. J. Lab. clin. Med. 1, 1 (1957) .
Sprue
Baker, S. T.: Tropical sprue. Brit. med. Bull. 28, 87 (1972) .
Baker, S. J., Ignatius, M., Mathan, V. I., Vaish, S. K., Chako, C. C.: Intestinal biopsy in tropical sprue. In: Ciba Foundation Study Group, No. 14, p. 84. Boston: Little, Brown 1962.
Gorbach, S. L., Mitra, R., Jacobs, B., Banwell, J. G., Chatterjee, B. D., Guha Mazumder, D. N.: Bacterial contamination of the upper small bowel in tropical sprue. Lancet I, 74 (1969) .
Gray, G. M., Walter, W. M., Jr., Colver, E. H.: Persistent deficiency of intestinal lactase in apparently cured tropical sprue. Gastroenterology 54, 552 (1968) .
O’brien, W., England, M. W. J.: Military tropical sprue from South-East Asia. Brit. med. J. II, 1157 (1966) .
Sheehy, T. W., Anderson, P. R.: Disaccharidase activity in normal and diseased small bowel. Lancet II, 1 (1965) .
Swanson, V. L., Thomassen, R. W.: Pathology of the jejunal mucosa in tropical sprue. Amer. J. Path. 46, 511 (1965) .
Wheby, M. S., Swanson, V. L., Bayless, T. M.: Comparison of ileal and jejunal biopsies in tropical sprue. Amer. J. clin. Nutr. 24, 117 (1971) .
Chronic Pancreatic Disease
Banwell, J. G., Hutt, M. S. R., Leonard, P., Blackman, V., Connor, D. W., Marsden, P., Campbell, J.: Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa. Gut. 8, 388 (1967) .
Bourgoignie, J., Sonet, J., Dechef, G.: Etude clinique du diabete sucre du Bantou de la region de Leopoldville. Ann. Soc. belge Med. Trop. 42, 261 (1962) .
Geevarghese, P. J., Pitchumoni, E. S.: Pancreatic diabetes in Kerala, India. Proceedings of the World Congress on Diabetes in the Tropics. Bombay, India. Edited by J. C. Patel and N. G. Talwalker, p. 223 (1966) .
Kajubi, S. K., Shaper, A. G., Owor, R.: Chronic Pancreatic Disease. Medicine in a Tropical Environment. Eds. Shaper, A. G., Kibukamusoke, J. W., Hutt, M. S. R. Brit. med. Ass., London 1972.
Kinnear, T. W. G.: The pattern of diabetes mellitus in a Nigerian teaching hospital. East African Medical Journal. 40, 288 (1963f) .
Owor, R.: Pathological features of chronic pancreatic disease in Uganda. East African Medical Journal 47, 604 (1970) .
Owor, R.: Chronic Pancreatic Disease: A common cause of obstructive jaundice. East African Medical Journal 49, 614 (1972).
Parson, W., Macdonald, F., Shaper, A. G.: African diabetics necropsied at Mulago Hospital, Kampala. 1957–1966. East African Medical Journal 45, 89 (1968).
Shaper, A. G.: Observations on the incidence and nature of chronic pancreatic disease in African diabetics in Uganda. Proceedings of the 4th Congress International Diabetes Federation, Geneva. 1, 119 (1961) .
Zuidema, P. J.: Cirrhosis and disseminated calcification of the pancreas in patients with malnutrition. Trop. geog. Med. 11, 70 (1959) .
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Hutt, M.S.R., Spencer, H. (1973). Malnutrition and Disorders of Intestinal Malabsorption. In: Tropical Pathology. Spezielle pathologische Anatomie, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00226-1_23
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DOI: https://doi.org/10.1007/978-3-662-00226-1_23
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