Zusammenfassung
Patientendaten aus klinischen Informationssystemen verschiedener Krankenhäuser zu analysieren, stellt in Deutschland und anderen europäischen Ländern eine große Herausforderung dar. Daher ist die Forschung und die Generierung von Real-Word Evidence (RWE) zwischen verschiedenen Standorten begrenzt. Federated Data Networks (FDNs) sind ein innovativer Ansatz zur verteilten, datenschutzkonformen, standort- und länderübergreifenden Analyse klinischer Daten aus mehreren Einrichtungen wie Krankenhäusern oder Registern. Als Voraussetzung für FDNs ist die Harmonisierung der Daten z. B. im OMOP Common Data Model (CDM) erforderlich. Das Hospital Del Mar (Barcelona, Spanien) beschreibt in diesem Kapitel die erfolgreiche Implementierung, den Nutzen und die vielfältige Verwendung des OMOP CDM in seiner Forschungseinrichtung. Das forschende Pharmaunternehmen Janssen hat das internationale Projekt HONEUR (Haematology Outcomes Network in Europe) ins Leben gerufen, welches das OMOP CDM nutzt. Die enge Zusammenarbeit zwischen klinischen, akademischen und technischen Partnern ermöglichen standort- und länderübergreifende, datenschutzkonforme Forschung mit dem Ziel, die Patientenversorgung zu verbessern.
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© 2024 Der/die Autor(en), exklusiv lizenziert an Springer Fachmedien Wiesbaden GmbH, ein Teil von Springer Nature
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Maaßen, O., Bardenheuer, K., Leis, A., Ramírez-Anguita, J.M., Bartz, H., Mayer, MA. (2024). HONEUR – Partnerschaftliche Datenanalyse von lokalen Real-World Daten. In: Henke, V., Hülsken, G., Schneider, H., Varghese, J. (eds) Health Data Management. Springer Gabler, Wiesbaden. https://doi.org/10.1007/978-3-658-43236-2_53
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