The idea to use ionizing radiation for cancer treatment is much older than commonly thought. In 1896, few months after Wilhelm Conrad Röntgen published his discovery of a new kind of rays [Röntgen, 1896], L. Freund and E. Schiff suggested to use these rays in the treatment of disease [MacKee, 1921]. From this, biologists and physicians started to investigate the biological effects of ionizing radiation. Physicists developed methods to increase the energy of the x-rays and highly sophisticated delivery techniques. Modern delivery techniques, namely Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) helped to tremendously reduce the dose delivered to healthy tissue and thus reduce side effects of radiotherapy.
KeywordsPositron Emission Tomography Monte Carlo Positron Emission Tomography Scanner Proton Therapy Treatment Room
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