Abstract
2-(O-chlorophenyl)-2- methvlaminocvclohexanone · HC1 (Ketamine, CI-581) is a member of the arylcycloalkylamines (Fig. 1). They area distinct class of centrally-acting drugs, the neuropharmacologic properties of which were uncovered ten years ago. 1-Phenyl(-1-cyclohexyl)piperidine (phencyclidine, Sernylan) was the first compound investigated in laboratory animals and subsequently studied in man as a general anesthetic agent [4, 8, 9, 12].
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Chen, G. (1969). The Pharmacology of Ketamine. In: Kreuscher, H. (eds) Ketamine. Anaesthesiology and Resuscitation / Anaesthesiologie und Wiederbelebung / Anesthésiologie et Réanimation, vol 40. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-99958-1_1
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DOI: https://doi.org/10.1007/978-3-642-99958-1_1
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