Abstract
Despite considerable controversy, the identities of the major mechanisms regulating aldosterone secretion are known and the broad outlines if not the details of how they operate are established. The release of this hormone from the zona glomerulosa of the adrenal cortex is increased by ACTH and by angiotensin II. The latter is formed in the blood stream by the action of renin from the kidney on a protein in the plasma. In addition to the hypothalamo-pituitary system and the renin-angiotensin system, a rise in plasma potassium or a fall in plasma sodium acts directly on the zona glomerulosa to increase aldosterone secretion. Additional stimulating and inhibiting factors from the posterior diencephalon and pineal gland may exist, but it now appears that, if they do, their physiological roles are minor.
The literature reviewed in this chapter includes for the most part only that available through March 1, 1964. The chapter includes previously unpublished results of experiments supported by United States Public Health Service Grants A-5437 and AM-06704.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literature
Abdul-Karim, R., and N. D. Assali: Pressor response to angiotonin in pregnant and nonpregnant women. Amer. J. Obstet. Gynec. 82, 246–251 (1961).
Allen, J. M.: A chemical and histochemical study of aliesterase in the adrenal gland of the developing mouse. Anat. Rec. 132, 195–205 (1958).
Amador, E., and G. C. Gil: Experimental production of acute sodium and water retention by the intact white rat. Metabolism 12, 653–658 (1963).
Anderson, C. H., M. McCally, and G. L. Farrell: The effects of atrial stretch on aldoster-one secretion. Endocrinology 64, 202–207 (1959).
Anderson, F. G., J. C. Johnson, and J. R. Derrick: A study of the dog’s blood pressure after unilateral renal vein constriction. Clin. Res. 10, 42 (1962).
Ando, T.: Adrenal structure and function with special reference to the relationship between zona glomerulosa and zona fasciculata. Endocr. jap. 4, 35–56 (1957).
Arndt, J. O., H. Reineck U. O. H. Gauer: Ausscheidungsfunktion und Hämodynamik der Nieren bei Dehnung des linken Vorhofes am narkotisierten Hund. Pflügers Arch. ges. Physiol. 277, 1–15 (1963).
Astarabadi, T.: Some experimental evidence for the dependence of the kidney on the pituitary gland. Acta endocr. (Kbh.), Suppl. 67, 169 (1962).
— The effect of growth and lactogenic hormones on renal compensatory hypertrophy in rats. Quart. J. exp Physiol. 48, 85–92 (1963).
Atkins, E. L., and J. W. Pearce: Mechanisms of the renal response to plasma volume expansion. Canad. J. Biochem. 37, 91–102 (1959).
August, J. T., and D.H. Nelson: Adjustment to aldosterone or desoxycorticosterone acetate induced sodium retention in patients with Addison’s disease. J. Clin. Invest. 38, 1964–1971 (1959).
— —, and G. W. Thorn: Reponse of normal subjects to large amounts of aldosterone. J. Clin. Invest. 37, 1549–1555 (1958a).
— —— Aldosterone. New Engl. J. Med. 259, 917–923, 967–971 (1958b).
Axelrad, B. J., and J. A. Luetscher, Jr.: Adrenal cortical activity in normal men on diets of low sodium content. J. clin. Invest. 33, 916 (1954).
Ayres, C. R., J. O. Davis, F. Lieberman, C. C. J. Carpenter, and M. Berman: The effects of chronic hepatic venous congestion on the metabolism of d,l-aldosterone and d-aldosterone. J. clin. Invest. 41, 884–895 (1962).
Ayres, P. J., O. Garrod, S. A. Tart, J. F. Tait, G. Walker, and W. H. Pearlman: The use of 16-3H-aldosterone in studies on human peripheral blood. Ciba Found. Coll. Endocr. 11, 309–326 (1957).
— R.C. Hurter, and E.S. Williams: Aldosterone excretion and potassium retention in subjects living at high altitude. Nature (Lond.) 191, 78–80 (1961).
Bacchus, H.: Cytochemical study of the adrenal cortex of the rat under salt stresses. Amer. J. Physiol. 163, 326–331 (1950).
Bachrach, D., E. B. Szabo, G. Y. Baradnay, and B. Korpassy: Histophysiological changes of the adrenal cortex of rat in dehydration and rehydration. J. Endocr. 23, 1–8 (1961).
Badinez, O., and H. Croxatto: Histological modifications of the adrenal cortex in the rat treated with potassium chloride and sodium chloride [Spanish]. Bol. Soc. Biol. Santiago 5, 40–43 (1948).
Bahn, R. C., H. E. Storino, and R. W. Schmit: The mass of the zona glomerulosa following complete anterior and posterior hypophysectomy and subtotal removal of the pars tuberalis in the dog. Endocrinology 66, 403–408 (1960).
Baïsset, A., L. Douste-Blazy, et P. Montastruc: Réduction de la sécrétion de l’aldostérone sous l’effet d’une distention auriculaire. J. Physiol. (Paris) 51, 393–394 (1959).
— — — et P. Valdigine: Recherches sur la régulation volumetrique de la sécrétion de l’aldostérone. Ann. Endocr. (Paris) 23, 419–424 (1962).
— — H. Planel et P. Montastruc: Cortex surrénal et diabéte insipide expérimental. C. R. Soc. Biol. (Paris) 148, 1867–1870 (1954).
Baldus, W. P., W. H. J. Summerskill, J. C. Hunt, and F. T. Maher: The renal circulation in cirrhosis: studies based on catheterization of the renal vein. J. clin. Invest. 42, 915 (1963).
Baldwin, D., H. D. Landahl, and T. B. Schwartz: The role of fluctuations of sodium balance in the regulation of body sodium stores. Metabolism 12, 1032–1050 (1963).
Bálint, P., and G. Pethes: Isosmotic hypervolemia and “water diuresis” in the dog. Acta med. scand. 163, 21–29 (1959).
Ball, W. D., and J. O. Davis: Failure of chronic adrenal venous congestion to produce sodium retention and increase aldosterone excretion in the dog. Amer. J. Physiol. 191, 339–341 (1957).
Barajas, L., and H. Latta: Juxtaglomerular apparatus in rats. Lab. Invest. 12, 1046–1059 (1963).
Baratz, R. A., and R. C. Ingraham: Renal hemodynamics and antidiuretic hormone release associated with volume regulation. Amer. J. Physiol. 198, 565–570 (1960).
Barbour, B. H.: Influence of salt on central nervous system control of steroidogenesis. Circulation 28, 687 (1963a).
—, and F. C. Bartter: Angiotensin labelled with I131 and with tritium. J. clin. Endocr. 23, 313–314 (1963).
— A. G. T. Casper, and F. C. Bartter: The role of salt in the interaction of steroidogenesis and angiotensin. Clin. Res. 10, 398 (1962a).
— — — The role of lymph in the control of steroidogenesis. Fed. Proc. 22, 210 (1963b).
Barbour, B. H. J. R. Gill, Jr., and F. C. Bartter: The effect of angiotensin II on sodium transport in the toad skin. Clin. Res. 10, 92 (1962b).
— — — J.D.H. Slater, and F.C. Bartter: An explanation for the antidiuresis produced by angiotensin II in man. Clin. Res. 10, 245 (1962c).
— J.D. H. Slater, A. G. T. Casper, and F. C. Bartter: Role of the kidney in the control of aldosterone secretion by dietary sodium. Circulation 26, 683–684 (1962d).
— D. Testerman, A. G. T. Casper, and F. C. Bartter: On the role of the central nervous system in control of adrenal cortical steroid production. Clin. Res. 11, 213 (1963c).
Barger, A. C., R. D. Berlin, and J. F. Tulenko: Infusion of aldosterone, 9-α-fluorohydrocortisone and antidiuretic hormone into the renal artery of normal and adrenalectomized dogs: effect on electrolyte and water excretion. Endocrinology 62, 804–815 (1958).
— F. E. Yates, and A. M. Rudolph: Renal hemodynamics and sodium excretion in dogs with graded valvular damage and in congestive failure. Amer. J. Physiol. 200, 601–608 (1961).
Barnes, A. C., and E. J. Quilligan: Measurements of aldosterone in eclamptogenic toxemias of pregnancy. Amer. J. Obstet. Gynec. 71, 670–682 (1956).
Baronofsky, I., J. Caravaca, and M. D. May: Urinary aldosterone output in dogs with renal hypertension. Clin. Res. 11, 42 (1963).
Barraclough, M. A., and N. F. Jones: Effect of fluid retention following vasopressin on sodium excretion by hypertensive subjects. Clin. Sci. 23, 433–440 (1962).
Barrett, A. M., and G. Sayers: Loss of ACTH activity following incubation of pituitary tissue: inhibition by glucagon and by pitressin. Endocrinology 68, 637–645 (1958).
Bartter, F. C.: The role of aldosterone in normal homeostasis and in certain disease states. Metabolism 5, 369–383 (1956).
— Regulation of the volume and composition of extracellular and intracellular fluid. Ann. N. Y. Acad. Sci. 110, 682–703 (1963).
— B. H. Barbour, A. A. Carr, and C. S. Delea: On the role of potassium in the regulation of aldosterone secretion. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964a.
Bartter, F. C, B. H. Barbour, A. A. Carr, and D. H. Suter: Control of adrenocortical steroid secretion dependent upon and independent of pituitary and kidneys. Canad. med. Ass. J. 90, 240–242 (1964b).
— E. G. Biglieri, P. Pronove, and C. S. Delea: Effect of changes in intravascular volume on aldosterone secretion in man. In: A. F. Müller and C. M. O’Connor (eds.), An Int. Symposium on Aldosterone, p. 100–110. London: J. & A. Churchill 1958.
Bartter, F. C, A. G. T. Casper, C. S. Delea, and J. D. H. Slater: On the role of the kidney in the control of adrenal steroid production. Metabolism 10, 1006–1020 (1961).
Bartter, F. C., and D. S. Gann: On the hemodynamic regulation of the secretion of aldosterone. Circulation 21, 1016–1023 (1960).
— G. W. Liddle, L. E. Dunoan, J. K. Barber, and C. Delea: The regulation of aldosterone secretion in man: the role of fluid volume. J. clin. Invest. 35, 1306–1316 (1956).
Bartter, F. C., I. H. Mills, E. G. Biglirri, and C. Delea: Studies on the control and physiologic action of aldosterone. Recent Progr. Hormone Res. 15, 311–344 (1959).
— —, and D. S. Gann: Increase in aldosterone secretion by carotid artery constriction in the dog and its prevention by thyrocarotid arterial junction denervation. J. clin. Invest. 39, 1330–1336 (1960).
— P. Pronove, J.R. Gill, Jr., and R. C. Maocardle: Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. Arner. J. Med. 33, 811–828 (1962).
Bean, J. W.: Specificity of the renin-hypertensinogen reaction. Amer. J. Physiol. 136, 731–742 (1942a).
— On the specificity of renin and some related phenomena. Fed. Proc. 1, 6–7 (1942b).
Beck, J. C., C. J. P. Giroud, I. Dyrenfurth, and E. H. Venning: Observations on the regulatory mechanisms of aldosterone secretion in man. Arch. intern. Med. 96, 463–469 (1955).
— E. E. Mcgarry, I. Dyrenfurth, and E. H. Venning: Metabolic effects of human and monkey growth hormone in man. Science 125, 884–885 (1957).
— — — — The metabolic effects of human and monkey growth hormone in man. Ann. intern. Med. 49, 1090–1105 (1958).
Bentley, P. J.: The adrenal cortex and renal sodium and potassium excretion in the newborn rat. J. Endocr. 26, 361–365 (1963).
Berliner, R. W.: The regulation of water balance and plasma sodium concentration. Arch. intern. Med. 102, 986–989 (1958).
Bernardis, L. L., and S. Kamura: Blood pressure and dietary sodium as regulators of juxtaglomerular cell function. Fed. Proc. 23, 445 (1964).
Berry, W. B., W. G. Austen, and W. D. Clark: Studies of the mechanism of action of angiotensin. Surg. Forum 14, 294–296 (1963).
Besch, P. K., K. A. Brownell, F. A. Hartman, and D. J. Watson: Adrenocortical steroid profile in the hypertensive dog. Acta endocr. (Kbh.) 39, 355–370 (1962).
Bianchi, A., A. F. de Sohaepdryver, G. R. de Vleesohouer, and P. Preziosi: On the pharmacology of synthetic hypertensine. Arch. int. Pharmacodyn. 124, 21–44 (1960).
Bickerton, R. K., and J. P. Buckley: Evidence for a central mechanism in angiotensin induced hypertension. Proc. Soc. exp. Biol. (N. Y.) 106, 843–836 (1961).
Biglieri, E. G., and W. F. Ganong: Effect of hypophysectomy on the adrenocortical response to bilateral carotid constriction. Proc. Soc. exp. Biol. (N. Y.) 106, 806–809 (1961).
— — Failure of aldosterone infusions to inhibit aldosterone secretion in hypophysectomized dogs. Excerpta Med. (Arnst.), Series 111 15, 223 (1962).
— S. Hane, P. E. Slaton Jr., and P. H. Forsham: In vivo and in vitro studies of adrenal secretion in Cushing’s syndrome and primary aldosteronism. J. clin. Invest. 42, 516–522 (1963).
— M. B. McIlroy, A. Naimark, and P. H. Forsham: Altered autonomic nervous system and renal response in primary aldosteronism. J. clin. Invest. 41, 1345 (1962).
— and P.E. Slaton, Jr.: Adrenal function in autonomic insufficiency. Clin. Res. 12, 88 (1964).
— C. O. Watlington, and P. H. Forsham: Sodium retention with human growth hormone and its subfractions. J. clin. Endocr. 21, 361–370 (1961).
Bilsel, Y. C., J. E. Wood, and R. D. Lange: Angiotensin II and erythropoiesis. Proc. Soc. exp. Biol. (N. Y.) 114, 475–479 (1963).
Bing, J.: Renal hypertension in rennin-depleted rats. Acta path. microbiol. scand. 56, 362–376 (1962a).
— Angiotensinase content of kidneys of normal and hypertensive rats. Acta path. microbiol. scand. 56, 385–387 (1962b).
—, and J. Kazimierczak: Renin content of different parts of the periglomerular circumference. Acta path. microbiol. scand. 50, 1–11 (1960).
— — Renin content of different parts of the juxtaglomerular apparatus. Acta path. Micro-biol. scand. 54, 80–84 (1962).
Birchard, W. H., J. D. Rosenbaum, and M. B. Strauss: Diuretic response to water ingestion in the presence of elevated serum electrolyte levels and expanded extracellular fluid volume. Amer. J. Med. 14, 496 (1953).
Biron, P., H. Chretien, E. Kiow, and J. Genest: Effects of angiotensin infusion on aldosterone and electrolyte excretion in normal subjects and patients with hypertension and adrenal cortical disorders. Brit. med. J. 1962 I, 1569–1575.
Biron, P., E. Kiow, F. O. Nowaczynski, J. Brouillet, and J. Genest: The effects of intravenous infusions of valine-5 angiotensin II and other pressor agents on urinary electrolytes and corticosteroids, including aldosterone. J. clin. Invest. 40, 338–347 (1961).
Black, D. A. K.: Renal factors in volume control. In: G. E. W. Wolstenholme and J. Etherington (eds.), Ciba Symposium on the Kidney, p.309–320. Boston: Little, Brown & Co. 1954.
Blair-West, J. R., J. P. Cogelan, and D. A. Denton: Evidence against an aldosterone feedback mechanism within the adrenal gland. Acta endocr. (Kbh.) 41, 61–66 (1962a).
— — — J. R. Goding, J. A. Munroe, R. E. Peterson, and M. Wintour: Humoral stimulation of adrenal cortical secretion. J. clin. Invest. 41, 1606–1627 (1962b).
— — — — — M. Wintour, and R. D. Wright: A useful method for collection of adrenal venous blood in conscious sheep. Endocrinology 71, 990–992 (1962c).
— — — — —, and R. D. Wright: The effect of neuraxial ablations upon the secretion of electrolyte-active steroid. J. Physiol. (Lond.) 153, 50P (1960).
— — — — — — The reduction of the pressor action of angiotensin II in sodium deficient conscious sheep. Aust. J. exp. Biol. med. Sci. 41, 369–376 (1963a).
— — — — M. Wintour, and R. D. Wright: The control of aldosterone secretion. Recent Progr. Hormone Res. 19, 311–383 (1963b).
— — — —, and R. D. Wright: The effect of aldosterone, cortisol and corticosterone upon the sodium and potassium content of sheep’s parotid saliva. J. clin. Invest. 42, 484–496 (1963c).
—, and J. R. Goding: Effect of temporary thoracic caval constriction on aldosterone secretion in conscious and in anesthetized sheep. Endocrinology 70, 822–836 (1962).
Blake, W. D., R. Wegria, H. P. Ward, and C. W. Frank: Effect of renal arterial constriction on excretion of sodium and water. Amer. J. Physiol. 163, 422–429 (1950).
Blaquier, P., D. F. Bohr, and S. W. Hoobler: Evidence against an increase in circulating pressor material in renal hypertensive rats. Amer. J. Physiol. 198, 1148–1152 (1960).
— — A. C. Taquini, Jr., and S. W. Hoobler: Renin and angiotensinase content of the kidney of normal and renal hypertensive rats. Proc. Soc. exp. Biol. (N. Y.) 108, 711–715 (1963).
— S. W. Hoobler, J. Schroeder, A. Gomez, and T. Kreulen: Effect of bilateral nephrectomy on the pressor response to renin. Amer. J. Physiol. 203, 339–343 (1962).
Bledsoe, T., D. P. Island, A. Riondel, and G. Liddle: Modification of aldosterone biosynthesis in man by a chemical inhibitor of 18-oxidation. Clin. Res. 11, 214 (1963).
Block, M. A., K. G. Wakim, and F. C. Mann: Renal function during stimulation of renal nerves. Amer. J. Physiol. 169, 670–677 (1952).
Blythe, W. B., and L. G. Welt: Dissociation between filtered load of sodium and its rate of excretion in the urine. J. clin. Invest. 42, 1491–1496 (1963).
Bock, K. D., and F. Gross: Renin and angiotensin tachyphylaxis. Circulat. Res. 9, 1044–1050 (1961).
Bohler, C. S., L. C. Chesley, F. P. Zuspan, E. Talledo, and P. Dow: Cardiovascular responsiveness to norepinephrine and angiotensin in pregnant women. Fed. Proc. 23, 357 (1964).
Bojesen, E.: Aldosterone in peripheral plasma of normal man. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
—, and H. Degn: A double isotope derivative method for the determination of aldosterone in peripheral plasma. Acta endocr. (Kbh.) 37, 541–558 (1961a).
— — Influence of changes of blood volume on the concentration of aldosterone in peripheral plasma of intact unanesthetized dogs. Nature (Lond.) 190, 352–353 (1961b).
Booth, E., J. W. Hinman, E. G. Daniels, M. Kosinski, and E. E. Muirhead: Antihypertensive renal factor. J. clin. Invest. 42, 918 (1963).
Boucher, R., P. Biron, and J. Genest: Procedure for isolation and determination of human blood angiotensin. Canad. J. Biochem. 39, 581–590 (1961).
— M. Launay, J. de Champlain, R. Veyrat, and J. Genest: A shorter method for isolation of human angiotensin. J. clin. Invest. 42, 919 (1963).
— R. Veyrat, J. de Champlain, and J. Genest: New procedures for measurement of human angiotensin and renin activity levels. Canad. med. Ass. J. 90, 194–201 (1964).
Bougas, J., C. Flood, B. Little, J. F. Tait, S. A. S. Tait, and R. Underwood: Dynamic aspects of aldosterone metabolism. In: E. E. Baulieu and P. robel (eds.), Aldosterone, p. 25–50. Oxford: Blackwell 1964.
Braun-Menéndez, E.: Pharmacology of renin and hypertensin. Pharmacol. Rev. 8, 25–55 (1956).
B raun-Menéndez, E., J. C. Fasciolo, L. F. Leloir, M. M. Munoz, and A. C. Taquini: Renal hypertension (Translated by L. Dexter.) Springfield (Ill.): Ch. C. Thomas 1946.
Bricker, N.S., R.A. Stratton, E.P. Mahoney, and J.P. Merrill: The functional capacity of the kidney denervated by autotransplantation in the dog. J. clin. Invest. 37, 185–193 (1958).
Brogi, M. P., and C. Pellegrino: The secretion of corticosterone and aldosterone by the rat adrenal cortex regenerating after enucleation. J. Physiol. (Lond.) 146, 165–178 (1959).
Brooks, F. P., and M. Pickford: Conditions under which the posterior pituitary hormones increase sodium and potassium excretion by the kidney. In: H. Heller (eds.), The neurophypophysis, p. 141–156. London: Butterworths 1957.
— — The effect of posterior pituitary hormones on the excretion of electrolytes in dogs. J. Physiol. (Lond.) 142, 468–493 (1958).
Brotchner, R. J.: Hypertension from obstruction of the aorta. Proc. Soc. exp. Biol. (N. Y.) 40, 264–265 (1939).
B rown, E., J. Hopper, Jr., and R. Wennesland: Blood volume and its regulation. Ann. Rev. Physiol. 19, 231–254 (1957).
Brown, J. J., D. L. Davies, P. B. Doak, A. F. Lever, and J. I. S. Robertson: Plasmarenin in normal pregnancy. Lancet 1963a II, 900–901.
— — A. F. Lever, R. A. Parker, and J. I. S. Robertson: Assay of renin in single glomerulirenin distribution in the normal rabbit kidney. Lancet 1963b II, 668–669.
— — —, and J. I. S. Robertson: Influence of sodium loading and sodium depletion on plasma renin in man. Lancet 1963c II, 278–279.
— — — — Variations in plasma renin concentration in several physiological and pathological states. Canad. med. Ass. J. 90, 201–206 (1964).
—, and W. S. Peart: The effect of angiotensin on urine flow and electrolyte excretion in hypertensive patients. Clin. Sci. 22, 1–17 (1962).
Brownell, K. A., F. A. Hartman, and R. W. Relman: Effect of adrenal enucleation on serum sodium. Endocrinology 47, 326–330 (1950).
Brunner, H., P. A. Desaulles, D. Regoli, and F. Gross: Renin content and excretory function of the kidney in rats with experimental hypertension. Amer. J. Physiol. 202, 795–799 (1962).
Bugnon, C., N. Moreau et R. Lenys: Recherches histophysiologiques sur les relations entre l’épiphyse et la zone glomerulaire du cortex surrenalien chez le rat blanc. Ann. Endocr. (Paris) 24, 348–355 (1963).
Bumpus, F. M., H. Schwarz, and I. H. Page: Synthesis and pharmacology of the octapeptide angiotonin. Science 125, 886–887 (1957).
— R. R. Smeby, and I. H. Page: Angiotensin, the renal pressor hormone. Circulat. Res. 9, 762–767 (1961).
— — —, and P. A. Khairallah: Distribution and metabolic fate of angiotensin II and various derivatives. Canad. med. Ass. J. 90, 190–193 (1964).
B uñag, R. D., S. L. Skinner, and J. W. McCubbin: Further observations on the release of renin by the kidney. Fed. Proc. 23, 467 (1964).
Burger, J. S., and W. N. Hess: Function of the rectal gland of the spiny dogfish. Science 131, 670–671 (1960).
Butterfield, J. L., and J. A. Richardson: Comparison of the effect of synthetic angiotensin (hypertensin) and I-norepinephrine on blood acid-base parameters. Pharmacologist 5, 259 (1963).
C ade, J. R., and T. Perenich: Aldosterone production by rats. Clin. Res. 12, 47 (1964).
— R. J. Shalhoub, M. Canessa-Fischer, and R. F. Pitts: Effect of strophanthidin on the renal tubules of dogs. Amer. J. Physiol. 200, 373–379 (1961).
Camargo, C. H., E. W. Hancock, A. J. Dowdy, and J. A. Luetscher, Jr.: Impaired metabolism of aldosterone in patients with congestive heart failure. Clin. Res. 12, 114 (1964).
C amp III, J. L.: Effect of posture on salt and water retention. II. Appearance of a circulating vasoconstrictor substance in the blood on assuming erect posture. J. Lab. clin. Med. 52, 202–205 (1958).
— F. Tate, P. B. Lowrance, and J. E. Wood, Jr.: Effects of posture on sodium and water retention. J. Lab. clin. Med. 52, 193–201 (1958).
Cara, J., and L. I. Gardner: Histopathology of adrenal hyperplasia. Pediatrics 32, 825–840 (1963).
C argill, W. H., W. B. Fackle, R. L. McWhorter, and J. V. Warren: Effect of abdominal compression on chloride excretion following administration of hypertonic saline solution. Amer. J. Med. 7, 413–414 (1949).
C arpenter, C. C. J., J. O. Davis, and C. R. Ayers: Concerning the role of arterial baroreceptors in the control of aldosterone secretion. J. clin. Invest. 40, 1160–1171 (1961b).
— — — Relation of renin, angiotensin II and experimental renal hypertension to aldosterone secretion. J. clin. Invest. 40, 2026–2042 (1961c).
Carpenter, C. C. J., J. O. Davis, J. E. Holman, C. R. Ayers, and R. C. Barn: Studies on the response of the transplant of kidneys and the transplant of adrenal gland to thoracic inferior vena cava constriction. J. clin. Invest. 40, 196–204 (1961a).
— — C. R. Wallace, and W. F. Hamilton: Acute effects of cardiac glycosides on aldosterone secretion in dogs with hyperaldosteronism secondary to chronic right heart failure. Circulat. Res. 10, 178–187 (1962).
Carr, A. A., B. H. Barbour, and F. C. Bartter: Effect of angiotensin on blood pressure. Lancet 1963 I, 1376–1377.
—, and F. C. Bartter: Effect of angiotensin II on adrenal ascorbic acid. Proc. Soc. exp. Biol. (N. Y.) 111, 210–212 (1962).
Carstensen, H., A. C. J. Burgers, and C. H. Li: Demonstration of aldosterone and corticosterone as the principal steroids formed in incubates of adrenals of the American bullfrog (Rana catesbeiana) and stimulation of their production by mammalian corticotrophin. Gen. compo Endocr. 1, 37–50 (1961).
Carter, W. T.: Effect of tilting on sodium excretion during salt loading in essential hypertension. Clin. Res. 11, 303 (1963).
C asey, J. H., E. Y. Bickel, and B. Zimmerman: The pattern and significance of aldosterone excretion by the postoperative surgical patient. Surg. Gynec. Obstet. 57, 179–183 (1957).
C astagnoli, N., Jr., A. Goldfien, and W. F. Ganong: Release of adrenal steroids during asphyxia. Fed. Proc. 20, 178 (1961).
Cater, D. B., and M. P. Stack-Dunne: The histological changes in the adrenal of the hypophysectomized rat after treatment with pituitary preparations. J. Path. Bact. 56, 119–133 (1953).
Cejka, V., L. A. de Vries, J. J. van Daatsebar, and J. G. G. Borst: The effect of aldosterone on aldosterone antagonism in patients with hypoaldosteronism produced by heparinoid (in Dutch). Ned. T. Geneesk. 106, 617–620 (1962).
— — M. E. Smorenberg-Schoorl, J. J. van Daatsebar, J. G. G. Borst, and C. L. H. Majoor: Effect of heparinoid and spirolactones on the renal excretion of sodium and aldosterone. Lancet 1960 I, 317–319.
Celander, O.: The range of control exercized by the sympathico-adrenal system. Acta physiol. scand. 32, Suppl. 116 (1954).
Champlain, J. de, R. Boucher, and J. Genest: Arterial angiotensin levels in edematous patients. Proc. Soc. exp. Biol. (N. Y.) 113, 932–937 (1963).
Chan, W. Y., and W. H. Sawyer: Saluretic actions of neurohypophysial peptides in conscious dogs. Amer. J. Physiol. 201, 799–803 (1961).
Chart, J. J., and H. Sheppard: Pharmacology and biochemistry of some amphenone analogues and other adrenocortical inhibitors. J. med. pharm. Chem. 1, 407–441 (1959).
— E. G. Shipley, and E. S. Gordon: Evidence for a sodium retaining factor in toxemia of pregnancy. Proc. Soc. exp. Biol. (N. Y.) 78, 244–246 (1951).
Cheek, D. B., and C. D. West: Natriuretic response and the distribution of body water during enforced hydration. Effect of renal denervation and desoxycorticosterone. Amer. J. Physiol. 179, 626 (1954).
Chesley, L. C., R. M. Wynn, and N.I. Silverman: Renal effects of angiotensin II infusion in normotensive pregnant and non-pregnant women. Circulat. Res. 13, 232–238 (1963).
Chester-Jones, I., J. G. Phillips, and D. Bellamy: Studies on water and electrolytes in cyclostomes and teleosts. Gen. comp Endocr., Suppl. 1, 36–47 (1962).
Chiandussi, L., A. Vaccarino, A. Greco, F. Muratori, L. Cesano, and D. Indovina: Effect of drug infusion on the splanchnic circulation. I. Angiotensin infusion in normal and cirrhotic Subjects. Proc. Soc. exp. Biol. (N. Y.) 112, 324–326 (1963).
Chien, S., B. Peric, and S. Usami: The reflex nature of release of antidiuretic hormone upon common carotid occlusion in vagotomized dogs. Proc. Soc. exp. Biol. (N. Y.) 111, 193–196 (1962).
Chimoskey, J. E., P. C. Blaquier, A. C. Taquini, and D. F. Bohr: Effects of angiotensin on pulmonary and systemic hemodynamics. Amer. J. Physiol. 202, 690–694 (1962).
Clementi, F., F. Fraschini, E. Mmuller, and A. Zambori: Pineal gland control of adrenal secretion; functional and morphological observations. Abstract Papers, Int. Roundtable Conference on the Epiphysis Cerebri, July 1963, p. 10–13.
Coghlan, J. P., D. A. Denton, J. R. Goding, and R. D. Wright: The control of aldosterone secretion. Postgrad. med. J. 36, 76–102 (1960).
Cohen, R. B., and J. D. Crawford: Glucose-6-phosphate dehydrogenase activity in the adrenal cortex of the sodium-depleted rat: a histochemical study. Endocrinology 70, 288–290 (1962a).
— — Distribution of glycogen, lipid and glucose-6-phosphate dehydrogenase activity in the adrenal cortex of the sodium-depleted rat: a histochemical study. Endocrinology 71, 847–852 (1962b).
Cohen, R. B., and J. D. Crawford: Glycogen in the adrenal cortex of sodium depleted rat. Proc. Soc. exp. Biol. (N.Y.) 109, 211–213 (1962c).
Collins, K. J.: Endocrine control of salt and water in hot conditions. Fed. Proc. 22, 716–720 (1963).
Conn, J. W.: Aldosteronism in man. Some clinical and climatological aspects. J. Amer. med. Ass. 183, 775–781, 871–878 (1963).
Cook, W., D. B. Gordon, and W. S. Peart: The location of renin in the rabbit kidney. J. Physiol. (Lond.) 135, 46P (1957).
—, and G. W. Pickering: Location of renin within kidney. J. Physiol. (Lond.) 135, 46P (1957).
— — A rapid method for separating glomeruli from rabbit kidney. Nature (Lond.) 182, 1103–1104 (1958b).
— — The location of renin in the rabbit kidney. In: M. Schachter (ed.), Polypeptides that affect smooth museles and blood vessels, p. 155–157. London: Pergamon 1960.
Cooper, G. W., and M. R. Nocenti: Unilateral renal ischemia and erythropoietin. Proc. Soc. exp. Biol. (N. Y.) 108, 546–549 (1961).
Cope, C. L., and E. Black: The hydrocortisone production in late pregnancy. J. Obstet. Gynaec. Brit. Emp. 66, 404–408 (1959).
— H. Hharwood, and J. Pearson: Aldosterone secretion in hypertensive diseases. Brit. med. J. 1962 I, 569–665.
—, and J. Pearson: Aldosterone secretion in severe renal failure. Clin. Sci. 25, 331–341 (1963).
Coppage, W. S., Jr., and A. E. Cooner: The effects of thyroid disease on aldosterone metabolism. Clin. Res. 11, 216 (1963).
— D. P. Island, A. E. Cooner, and G. W. Liddle: The metabolism of aldosterone in normal subjects and in patients with hepatic cirrhosis. J. clin. Invest. 41, 1672–1680 (1962).
Corbascio, A. N.: Action of long chain polymers in kidney juxtaglomerular cells and connective tissue mast cells. Circulat. Res. 8, 390–398 (1960).
Cox, J. R., G. A. B. Davies-Jones, P. J. Leonard, and B. Singer: The effect of positive pressure respiration on urinary aldosterone excretion. Clin. Sci. 24, 1–5 (1963).
— P. J. Leonard, and B. Singer: Effect of vasopressin on the volume of body fluid compartments and its relation to aldosterone excretion. Clin. Sci. 21, 205–219 (1961).
— — — Changes in sodium distribution in body fluid compartments and urinary aldosterone excretion. Clin. Sci. 23, 13–26 (1962).
Crabbé, J., W. J. Reddy, E. J. Ross, and G. W. Thorn: The role of the adrenal cortex in the normal adaptation to dietary sodium deprivation J. clin. Endocr. 18, 1147–1158 (1958a).
— — — — The stimulation of aldosterone secretion by adrenocorticotropic hormone (ACTH). J. clin. Endocr. 19, 1185–1191 (1959).
— E. J. Ross, and G. W. Thorn: The significance of the secretion of aldosterone during dietary sodium deprivation in normal subjects. J. clin. Endocr. 18, 1159–1177 (1958b).
Craig, R. L., N. Wetzel, and R. G. Bianchi: Renal function studies in the dog hypophysectomized for ascites. Amer. J. Physiol. 200, 890–892 (1961).
Cranston, W. I., and W. Brown: Diurnal variation in plasma volume in normal and hypertensive subjects. Clin. Sci. 25, 107–114 (1963).
Cressman, R. D., and A. Blalock: Experimental hypertension. Effects of Kieselguhr injection and splanchnic stimulation. Proc. Soc. exp. Biol. (N.Y.) 40, 258–260 (1939).
Crocker, D. W., R. A. Newton, E. M. Mahoney, and J. H. Harrison: Hypertension due to primary renal ischemia. New Engl. J. Med. 267, 794–800 (1962).
Dahl, L. K.: Salt intake and salt need. New Engl. J. Med. 258, 1152–1159 (1958).
— L. Sslver, S. Sparagen, and M. Smilay: Effect of chronic high and low salt intake on adrenocortical function. Nature (Lond.) 190, 348–349 (1961).
Dailey, R.E., E. R. Karickhoff, L. Swell, H. Field, Jr., and C. R. Treadwell: Metabolism of cortisol by the liver of sodium deficient rats. Proc. Soc. exp. Biol. (N. Y.) 105, 326–328 (1960).
Daily, W. J. R., and W. F. Ganong: The effect of ventral hypothalamic lesions on sodium and potassium metabolism in the dog. Endocrinology 62, 442–454 (1958).
Das Gupta, D., N. Kalant, and C. J. P. Gmoud: Experimental aminonucleoside nephrosis (II); effect of adrenalectomy on fluid retention of aminonucleoside nephrosis. Proc. Soc. exp. Biol. (N. Y.) 100, 602–604 (1959).
Daughaday, W. H.: Steroid protein interactions. Physiol. Rev. 39, 885–902 (1959).
— J. Holloszy, and I. K. Martz: Binding of corticosterone by plasma protein. J. clin. Endocr. 21, 53–61 (1961).
Davidson, E. T., F. de Venuto, and V. Westphal: Steroid-protein interactions IX: Interactions of aldosterone with human serum proteins in conjunction with spirolactones and other steroids. Endocrinology 71, 893–900 (1962).
Davis, J. O.: Some aspects of the physiology of aldosterone. J. nat. med. Ass. (N.Y.) 49, 42–50 (1957).
— Mechanisms of salt and water retention in congestive heart failure. Amer. J. Med. 29, 486–507 (1960a).
— Hormonal control of aldosterone secretion. In: J. H. Moyer and M. Fuchs (eds.), Edema, p. 113–120. Philadelphia: Saunders 1960b.
— A critical evaluation of the role of receptors in the control of aldosterone secretion and sodium excretion. Progr. cardiovasc. Dis. 4, 27–46 (1961a).
— Mechanisms regulating the secretion and metabolism of aldosterone in experimental secondary hyperaldosteronism. Recent Progr. Hormone Res. 17, 293–331 (1961b).
— Adrenocorticoid and renal hormonal function in experimental cardiac failure. Circulation 25, 1002–1014 (1962a).
— The control of aldosterone secretion. Physiologist 5, 65–86 (1962b).
— The regulation of aldosterone secretion. Physiol. Physicians 1, No 5 (1963a).
— The role of the adrenal cortex and the kidney in the pathogenesis of cardiac edema. Yale J. Biol. Med. 35, 402–428 (1963b).
— E. Anderson, C. C. J. Carpenter, C. R. Ayers, W. Haymaker, and W. T. Spence: Aldosterone and corticosterone secretion following midbrain transection. Amer. J. Physiol. 200, 437–443 (1961a).
— C. R. Ayers, and C. C. J. Carpenter: Renal origin of aldosterone stimulating hormone in dogs with thoracic caval constriction and in sodium depleted dogs. J. clin. Invest. 40, 1466–1474 (1961b).
— The renin-angiotensin system in the control of aldosterone secretion. Physiologist 4, 27 (1961c).
— R. C. Bahn, and W. C. Ball: Subacute and chronic effects of hypothalamic lesions on aldosterone and sodium excretion. Amer. J. Physiol. 197, 387–390 (1959a).
— — M. J. Goodkind, and W. C. Ball, Jr.: Aldosterone excretion in urine from hypophys. ectomized dogs with thoracic inferior vena cava constriction. Amer. J. Physiol. 191, 329–338 (1957).
— — N. A. Yankopoulos, B. Kliman, and R. E. Peterson: Acute effects of hypophys. ectomy and diencephalic lesions on aldosterone secretion. Amer. J. Physiol. 197, 380–386 (1959b).
—, and W. C. Ball, Jr.: Effects of a body cast on aldosterone and sodium excretion in dogs with experimental ascites. Amer. J. Physiol. 192, 536–542 (1958).
— — R. C. Bahn, and M. J. Goodking: Relationship of adrenocortical and anterior pitui. tary function to fecal excretion of sodium and potassium. Amer. J. Physiol. 196, 149–152 (1959c)
— C. C. J. Carpenter, and C. R. Ayers: Relation of renin and angiotensin II to the control of aldosterone secretion. Circulat. Res. 11, 171–184 (1962a).
—, and R. C. Bahn: Relation of anteroir pituitary function to aldosterone and corticosterone secretion in conscious dogs. Amer. J. Physiol. 199, 212–216 (1960a).
— — — J. E. Holman, and R. C. Bahn: Evidence for secretion of an aldosterone-stimulating hormone by the kidney. J. clin. Invest. 40, 684–696 (1961d).
— P. H. Hartroft, E. O. Titus, C. C. J. Carpenter, C. R. Ayers, and M. E. Spiegel: The role of the renin-angiotensin system in the control of aldosterone secretion. J. clin. Invest. 41, 378–389 (1962b).
— J. E. Holman, C. C. J. Carpenter, J. Urquhart, and J. T. Higgins, Jr.: The extra-adrenal factor essential for chronic renal sodium retention in the presence of increased sodium.retaining hormone. Circulat. Res. 14, 17–31 (1964a).
— D. S. Howell, and R. E. Hyatt: Effect of chronic pitressin administration on electrolyte excretion in normal dogs and in dogs with experimental ascites. Endocrinology 55, 409–416 (1954).
— B. Kliman, N. A. Yankopoulos, and R. E. Peterson: Increased aldosterone secretion following acute constriction of the inferior vena cava. J. clin. Invest. 27, 1783–1790 (1958).
— J. Urquhart, and J. T. Higgins, Jr.: The effects of alterations of plasma sodium and potassium concentration on aldosterone secretion. J. clin. Invest. 42, 597–609 (1963).
— — — Renin, angiotensin and aldosterone in experimental secondary hyperaldosteronism. Canad. med. Ass. J. 90, 245–248 (1964b).
— — — E. Rubin, and P. M. Hartroft: Hypersecretion of aldosterone in dogs with a chronic-caval fistula and high output heart failure. Circulat. Res. 14, 471–485 (1964c).
— N. A. Yankopoulos, and J. Holman: Chronic effects of carotid sinus denervation, cervical vagotomy and aortic depressor nerve section on aldosterone and sodium excretion. Amer. J. Physiol. 197, 207–210 (1959d).
Davis, J.O., N. A. Yankopoulos, F. Lieberman, J. Holman, and R. C. Bahn: The role of the anterior pituitary in the control of aldosterone secretion in experimental secondary hyperaldosteronism. J. clin. Invest. 39, 765–775 (1960b).
Davis, L., E. Fischer, R. Brechner, and A. S. Biddle: Effect of hypotensive drugs and hypophysectomy upon the adrenal cortex of normal and hypertensive dogs. Ann. Surg. 153, 877–886 (1961).
Deane, H. W.: Physiological regulation of the zona glomerulosa of the rat’s adrenal cortex, as revealed by cytochemical observations. In: R. C. christman (ed.), Pituitary-adrenal function, p. 31–38. Washington: Amer. Ass. Advanc. Sci. 1951.
—, and A. C. Barger: Histophysiology of the adrenal cortex in dogs with mild and severe cardiac damage. Endocrinology 61,758–764 (1957).
—, and R. O. Greep: A morphological and histochemical study of the rat’s adrenal cortex after hypophysectomy, with comments on the liver. Amer. J. Anat. 19, 112–146 (1946).
— — A cytochemical study of the adrenal cortex in hypo- and hyperthyroidism. Endocrinology 41, 243–257 (1947).
— F. G. Hofmann, A. K. Solomon, and G. B. Wislocki: Selective uptake of silver by the adrenal zona glomerulosa. Anat. Rec. 121, 283 (1955).
—, and G. M. C. Masson: Adrenal cortical changes in rats with various types of experimental hypertension. J. clin. Endocr. 11, 193–208 (1951).
— R. H. Schneiweiss, and L. I. Gidez: Response of rat zona glomerulosa in experimental nephrosis. Proc. Soc. exp. Biol. (N. Y.) 104, 417–419 (1960).
— J. H. Shaw, and R. O. Greep: The effect of altered sodium or potassium intake on the width and cytochemistry of the zona glomerulosa of the rat’s adrenal cortex. Endocrinology 43, 133–153 (1948).
Del Greco, F.: Effects of valine-5 angiotensin II on excretion of water and salt in primary and secondary hypertension. Proc. Soc. exp. Biol. (N. Y.) 107, 943–946 (1961).
— Comparative effect of valine-5 angiotensin II amide and pitressin on renal excretory function in diabetes insipidus. Proc. Soc. exp. Biol. (N. Y.) 109, 105–110 (1962).
—, and I. H. Page: Effects of intrarenal infusion of angiotensin in the dog. Circulation 24, 917 (1961).
Delost, P., H. Delost et T. Terroine: Involution de la zone glomerulée surrénalienne dans la carence en B1 J. Physiol. (Paris) 51, 445–446 (1959).
Deming, Q. B., and J. A. Leutscher, Jr.: Bioassay of desoxycorticosteronelike material in urine. Proc. Soc. exp. Biol. (N.Y.) 73, 171–175 (1950).
Ddemopoulos, H. B., and G. Kaley: The role of renal juxtaglomerular cells in the elaboration of erythropoietin. Fed. Proc. 23, 183 (1964).
Denton, D. A., J. R. Goding, and R. D. Wright: Control of adrenal secretion of electrolyteactive steroids. Brit. med. J. 1959 II, 447–456, 522–530.
— — — The control of aldosterone secretion. In: E. B. astwood (ed.), Clinical endocrinology, I, p. 373–396. New York: Grune & Stratton 1960.
Deodhar, S. D.: Immunological production of anti-angiotensin. I. Preparation of angiotensin-protein complex antigen. J. exp Med. 111, 419–427 (1960a).
— Immunological production of anti-angiotensin. II. Production and detection of antiangiotensin. J. exp Med. 111, 429–439 (1960b).
Dexter, L.: Mechanism of human hypertension. Amer. J. Med. 4, 279–284 (1948).
Doe, R. P., E. B. Flink, and M. G. Goodsell: Relation of diurnal variation in 17-OH-corticosteroid levels in blood and urine to eosinophils and electrolyte excretion. J. clin. Endocr. 16, 196–206 (1956).
Ddougherty, T. F.: Relation of adrenal cortical stimulation to histological alterations in the kidneys and cardiovascular tissues of mice. Macy Conference on factors regulating blood pressure 2, 17–40 (1948).
Driscol, T. E., M. M. Maultsby, G. L. Farrell, and R. M. Berne: Aldosterone secretion in experimental congestive heart failure. Amer. J. Physiol. 191, 140–144 (1957).
Dumont, A. E., and J. H. Mulholland: Effect of thoracic duct to esophagus shunt in dogs with vena cava constriction. Amer. J. Physiol. 204, 289–290 (1963).
Duncan, L. E., G. W. Liddle, and F. C. Bartter: The effect of changes in body sodium on extracellular fluid volume and aldosterone and sodium excretion by normal and edematous men. J. clin. Invest. 35, 1299–1305 (1956).
Dunihue, F. W., M. Bloomfield, and B. Machanic: Effect of mineralocorticoids and of adrenocorticotrophin on the granularity of juxtaglomerular cells. Endocrinology 72, 963–965 (1963a).
— — and W. van B. Robertson: Effect of reserpine and catecholamines on juxtaglomerular cells in rats fed normal and low sodium diets. Endocrinology 69, 934–938 (1961).
Dunihue, F. W., W. van B. Robertson, and B. Macranic: Effects of adrenal enucleation and of the spirolactone SC 8109 on granularity of rat juxtaglomerular cells. Endocrinology 72, 859–864 (1963b).
Dustan, H. P., I. H. Page, E. F. Poutasse, and L. Wilson: An evaluation of treatment of hypertension associated with occlusive renal arterial disease. Circulation 27, 1018–1027 (1963).
Dyrenfurth, I., A. J. Blair, J. C. Beck, and E. H. Venning: Studies in patients with adrenal cortical hyperfunction. J. clin. Endocr. 20, 735–750 (1960).
— C. H. Stacey, J. C. Beck, and E. H. Venning: Aldosterone excretion in patients with cirrhosis of the liver. Metabolism 6, 544–555 (1957).
—, and E. H. Venning: Studies on the assay of aldosterone: chromatography and chemical determination. Endocrinology 64, 648–663 (1959).
Earle, D. P., R. C. de Bodo, I. L. Schwartz, S. J. Farber, M. Kurtz, and J. Green-Berg: Effect of hypertension on electrolyte and water metabolism in the dog. Proc. Soc. exp. Biol. (N. Y.) 76, 608–612 (1951).
Edelman, R., and P. M. Hartroft: Localization of renin in juxtaglomerular cells of rabbit and dog through the use of fluorescent-antibody technique. Circulat. Res. 9, 1069–1077 (1961).
Egdahl, R. H.: Corticosterone secretion following caval constriction in dogs with isolated pituitaries. Endocrinology 68, 226–231 (1961).
Eilers, E. A., and R. E. Peterson: Control of aldosterone secretion in the rat. Endocrine Society, Abstracts of the 46th Meeting 1964, p. 62.
Eisenstein, A. B.: Effect of sodium chloride feeding on adrenocortical hormone secretion of salt deprived rats. Proc. Soc. exp. Biol. (N. Y.) 101, 850–852 (1959).
—, and I. Strack: Effect of sodium deficiency on secretion of hormones by the rat adrenal cortex. Endocrinology 68, 121–124 (1961).
EndröCZI, E., K. LissáK, and M. Terkeres: Hormonal “feedback” regulation of pituitaryadrenal cortex activity. Acta physiol. Acad. Sci. hung. 18, 291–299 (1961).
Epstein, F. H.: Acute tubular necrosis-acute renal failure. In: T. R. Harrison, R. D. Adams, I. L. Bennett, Jr., W. H. Resnik, G. W. Thorn and M. M. Wintrobe (eds.), Principles of internal medicine, 4th ed. p. 1493–1498. New York: McGraw-Hill 1962.
Erankö, O.: Short term effects of potassium, sodium and ACTH on the histochemistry of the adrenal gland of rats. Acta endocr. (Kbh.) 18, 189–200 (1955).
Fachet, J., E. Stark, K. Vallent, and M. Palkovits: Some observations on the functional interrelation between the thymus and the adrenal cortex. Acta med. Acad. Sci. hung. 18, 461–471 (1962).
FäNGE, R., K. Schmidt-Nielsen, and M. Robinson: Control of secretion from the avian salt gland. Amer. J. Physiol. 195, 321–326 (1958).
Falbriard, A., A. F. Muller, R. Neher et R. S. Mach: Etude des variations de l’aldostér-onurie sous l’effect de surcharges en potassium et de déperditions renales et extrarénales de sel et d’eau. Schweiz. med. Wschr. 85, 1218–1220 (1955).
Falkheden, T.: Renal function following hypophysectomy in man. Acta endocr. (Kbh.) 42, 571–590 (1963).
Farrell, G.: Regulation of aldosterone secretion. Physiol. Rev. 38, 709–728 (1958).
— Steroidogenic properties of extracts of beef diencephalon. Endocrinology 65, 29–33 (1959a).
— The physiological factors which influence the secretion of aldosterone. Recent Progr. Hormone Res. 15, 275–298 (1959b).
— Adrenoglomerulotropin. Circulation 21, 1009–1015 (1960a).
— Epiphysis cerebri in the control of steroid secretion. Fed. Proc. 19, 601–604 (1960b).
— Recent contributions to the study of the role the central nervous system in aldosterone secretion. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
— R. C. Banks, and S. Koletsky: The effect of corticosteroid injection on aldosterone secretion. Endocrinology 58, 104–108 (1956a).
—, and W. M. McIsaac: Adrenoglomerulotropin. Arch. Biochem. 94, 543–544 (1961).
—, and E. W. Rauschkolb: Neural control of endocrine function. Ann. Rev. Med. 12, 323–334 (1961).
— R. S. Rosnagle, and E. W. Rauschkolb: Increased aldosterone secretion in response to blood loss. Circulat. Res. 4, 606–611 (1956b).
—, and P. C. Royce: Secretion of aldosterone by the adrenal of the dog. Effects of hypophy-sectomy and ACTH. Amer. J. Physiol. 182, 269–272 (1955).
— P. C. Royce, E. W. Rauschkolb, and H. Hirschmann: Isolation and identification of aldosterone from adrenal venous blood. Proc. Soc. exp. Biol. (N.Y.) 87, 141–143 (1954).
—, and A. N. Taylor: Neuroendocrine aspects of blood volume regulation. Ann. Rev. Physiol. 24, 471–490 (1962).
Fasoiolo, J. C., and A. C. Taquini: Action of partial ischemia on the renin content of kidneys (in Spanish). Medicina (B. Aires). 10, 452–457 (1950).
—, E. De Vito, and I. Gómez: Renin, hormone of the kidney. Acta physiol. lat.-amer. 12, 348–349 (1962).
—, —, J. C. Romero, and J. M. Cucchi: The renin content of the blood of humans and dogs under several conditions. Canad. med. Ass. J. 90, 206–209 (1964).
Fasola, A. F., and D. M. Helmer: Effect of exercise on renin content of plasma of normotensive and hypertensive subjects. Physiologist 6, 178 (1963).
Fejfar, Z.: Water and electrolyte metabolism in congestive heart failure. Ciba Foundation Colloquium on Aging 4, 271–298 (1958).
Feldberg, W., and G. P. Lewis: Release of adrenaline from cat’s suprarenals by bradykinin and angiotensin. J. Physiol. (Lond.) 167, 46P–47P (1963).
Finkel, M. J.: Human growth hormone. Amer. J. Med. 32, 588–598 (1962).
Finnerty, F. A., G. D. Massero, V. Chupkovich, and J. Tuckman: Evaluation of the pressor, cardiac and renal hemodynamic properties of angiotensin II in man. Circulation 9, 256–263 (1961).
Fisher, E. R., and H. Z. Klein: Effect of renal hypertension in sodium deficient rats on juxtaglomerular index and zona glomerulosa. Proc. Soc. exp. Biol. (N.Y.) 113, 37–39 (1963).
—, —: Effect of sodium on juxtaglomerular index and zona glomerulosa in experimental nephrosis. Proc. Soc. exp. Biol. (N.Y.) 114, 541–544 (1963).
—, E. R, and G. M. C. Masson: Renal lesions in renin proteinuria. Arch. Path. 71, 480–484 (1961).
Fisher, J. W., and J. J. Crook: Influence of several hormones on erythropoiesis and oxygen consumption in the hypophysectomized rat. Blood 19, 557–565 (1962).
Fishman, R. A.: The failure of intracranial pressure-volume changes to influence renal function. J. clin. Invest. 32, 847–851 (1953).
Fitz, A. E., and M. L. Armstrong: Plasma vasoconstrictor activity in patients with renal, malignant, and primary hypertension. Clin. Res. 10, 288 (1962).
Fitzhugh, F. W., R. Huie, and A. J. merrill: Endocrine factors in congestive heart failure. Amer. J. Med. 33, 644 (1952).
Fleming, R., and G. L. Farrell: Aldosterone and hydrocortisone secretion by the denervated adrenal. Endocrinology 59, 360–363 (1958).
Floyer, M. A.: The role of the kidney in the mechanism of experimental hypertension. In: G. E. W. Wolstenholme and M. P. Cameron (eds.), Ciba Symposium on Hypertension, p. 155–171. Boston: Little, Brown & Co. 1954.
Földvári, I. P., E. Czeizel, G. Simon, M. Palkóvits, and P. Kortai: The influence of the sub commissural organ on the resorption of water and electrolytes from the small intestine. Acta physiol. Acad. Sci. hung. 21, 43–50 (1962).
Foglia, V.G., and J.L. Moglia: Action of hypertension on the plasma glucose and potassium (in Spanish). Rev. Soc. argent. Biol. 16, 529–536 (1940).
Fordham, C. C., III, and M. Newton: Response of salt-loaded rats to abrupt withdrawal of salt. Amer. J. Physiol. 205, 467–470 (1963).
Forsham, P. H., V. C. Di Raimondo, F. G. Biglieri, and C. H. Li: Adrenocorticotropic activity of a synthetic nonadecapeptide (NDP) in man. Metabolism 10, 335–338 (1961).
Fortier, C.: Adenohypophysis and adrenal cortex. Ann. Rev. Physiol. 24, 223–258 (1962).
Fourman, P.: The adrenal cortex and the kidney. In: D. A. K. Black (ed.), Renal diseases, p. 213–241. Philadelphia: Davis 1962.
Franken, F. H., u. H. Zimmerman: Aldosterone, cortisol und cortison im Harn und in operativ entfernten Nebennieren bei Patienten mit Cushing-Syndrom. Acta endocr. (Kbh.) 41, 531–545 (1962).
Fredrickson, D. S., R. E. Peterson, and D. Steinberg: Inhibition of adrenocortical steroid secretion by delta-4-cholestenone. Science 127, 704–705 (1958).
Freed, S. C., and S. St. GEORGE: Adrenal cortex in the maintenance of hypertension. Endocrinology 71, 422–424 (1962).
Fregly, M. J., R. L. Brimhall, and O. J. Galindo: Effect of the antithyroid drug, propylthiouracil, on the sodium balance of rats. Endocrinology 71, 693–700 (1962).
Friedman, M., and A. Kaplan: Studies concerning the site of renin formation in the kidney. I. The absence of renin in the aglomerular kidney of the midshipman fish. J. exp Med. 75, 127–134 (1942).
Gabelman, E. H., and P. A. Rondell: Mechanisms effecting the protracted pressor response to angiotensin in nephrectomized rats. Fed. Proc. 23, 514 (1964).
Gann, D. S., and F. C. Bartter: Buffer function of the nerves arising at the thyrocarotid arterial junction in the dog. Amer. J. Physiol. 197, 1229–1232 (1959).
—, —: Increase in aldosterone secretion by acute denervation of the thyrocarotid arterial junction. Amer. J. Physiol. 199, 193–194 (1960).
Gann, D. S., J.F. Cruz, A. G. T. Casper, and F. C. Bartter: Mechanism by which potassium increases aldosterone secretion in the dog. Amer. J. Physiol. 202, 991–996 (1962a).
—, K. L. Gould, and J. V. Mumma: On the role of vagal and carotid receptors in the control of adrenal corticoid secretion in the dog. Clin. Res. 10, 296 (1962b).
—, B. Kingsbury, W. R. Drucker, and R. H. Travis: Diminished adrenal corticoid response to burn and ACTH in the nephrectomized dog. Proc. Soc. exp. Biol. (N.Y.) 108, 99–103 (1961).
—, I. H. Mills, J. F. Cruz, A. G. T. Casper, and F. C. Bartter: On the mechanisms of decrease of aldosterone secretion in the dog. Proc. Soc. exp. Biol. (N.Y.) 105, 158–161 (1960).
—, and E. S. Redgate: Failure of angiotensin to deplete adrenal ascorbic acid. Physiologist 4, 39 (1961).
—, and R. H. Travis: Dissociation of response of aldosterone and hydrocortisone secretion to carotid constriction in the dog. Endocr. Soc. Abstracts, p. 2 (1963).
—, and H. K. Wright: Effects of hemorrhage and extracellular fluid volume depletion on sodium metabolism and urinary concentrating ability. Fed. Proc. 23, 463 (1964).
Ganong, W. F.: The effect of ACTH on adrenal size in hypophysectomized rats after removal of one adrenal. Endocrinology 55, 117–120 (1954).
—: Review of medical physiology. Los Altos, California: Lange Med. Publ. 1963a.
—: The central nervous system and the synthesis and release of adrenocorticotropic hormone. In: A. V. Nalbandov (ed.), Advances in neuroendocrinology, p. 92–148. Urbana: U. Illinois Press 1963b.
—, W. F. Bernhard, and J. D. Mcmurray: The effect of hypothermia on the output of 17–hydroxycorticoids from the adrenal vein in the dog. Surgery 38, 506–512 (1955).
—, A. Boryczka, R. Shackleford, R. N. Clark, and R. P. Converse: Effect of dietary salt restriction on the adrenocortical response to ACTH. Proc. Soc. exp. Biol. (N.Y.) 118, 792–794 (1965b).
—, E. E. van Brunt, T. C. Lee, and E. G. Biglieri: Inhibition of aldosterone-stimulating activity of hog and dog renin by plasma of dogs treated with hog renin. Fed. Proc. 22, 631 (1963a).
—, —, —, and P. J. Mulrow: Inhibition of aldosterone-stimulating activity of hog and dog renin by the plasma of dogs immunized with hog renin. Proc. Soc. exp. Biol. (N.Y.) 112, 1062–1064 (1963b).
—, and P. H. Forsham: Adenohypophysis and adrenal cortex. Ann. Rev. Physiol. 22, 579–614 (1960).
—, T. C. Lee, E. E. van Brunt, and E. G. Biglieri: Aldosterone secretion in dogs immunized with hog renin. Endocrinology 76, 1141 (1965a).
—, A. H. Lieberman, W. J. R. Daily, Y. S. Yuen, P. J. Mulrow, J. A. Luetscher, Jr., and R. E. Bailey: Aldosterone secretion in dogs with hypothalamic lesions. Endocrinology 65, 18–28 (1959).
—, and P. J. Mulrow: Rate of change in sodium and potassium excretion after injection of aldosterone into the aorta and renal artery of the dog. Amer. J. Physiol. 195, 337–342 (1958).
—, and —: Evidence of secretion of an aldosterone-stimulating substance by the kidney. Nature (Lond.) 190, 1115–1116 (1961).
—, and —: The role of the kidney in the adrenocortical response to hemorrhage in hypophysectomized dogs. Endocrinology 70, 182–188 (1962a).
—, and —: The effect of aortic constriction on aldosterone secretion in hypophysectomized dogs. J. clin. Invest. 41, 1503–1508 (1962b).
—, —, A. Boryczka and G. Cera: Evidence for a direct effect of angiotensin II on the adrenal cortex of the dog. Proc. Soc. exp. Biol. (N.Y.) 109, 381–384 (1962).
—, A. M. Nolan, A. Dowdy, and J.A. Luetscher, Jr.: The effect of hypothalamic lesions on adrenal secretion of cortisol, corticosterone, 11-desoxy-cortisol and aldosterone. Endocrinology 68, 169–171 (1961a).
—, Y. S. Yuen, R. S. Stevenson, W. J. R. Daily, and J. M. Davidson: The effect of diencephalic and frontal lobe lesions on sodium metabolism in dogs. Arch. Neurol. 4, 182–189 (1961b).
Garber, B. S., F. W. Mccoy, E. R. Hayes, and B. H. Marks: Pharmacological studies on the renal juxtaglomerular apparatus. Arch. into Pharmacodyn. 121, 275–286 (1959).
Garcia, J. F., and J. C. Schooley: Immunological neutralization of various erythropoietins. Proc. Soc. exp. Biol. (N.Y.) 112, 712–714 (1963).
Gardner, L. I., H. Berman, and H. W. Deane: Metabolic competition between desoxy corticosterone acetate and strophanthin-G in the rat. Endocrinology 55, 417–425 (1954).
Gaskell, J. R., R. K. Jones, and A. P. Shapiro: Hyper-responsiveness of renal hypertensive rats to intravenous angiotensin II. Proc. Soc. exp. Biol. (N.Y.) 115, 179–182 (1964).
Gauer, O. H., and J. P. Henry: Circulatory basis of fluid volume control. Physiol. Rev. 43, 423–481 (1963).
Gault, C. L., and R. E. Ecklund: Significance of aldosterone antagonists in the treatment of edema and ascites. Amer. J. Med. 33, 490–500 (1962).
Gaunt, R., J. J. Chart, and A. A. Renzi: Endocrine pharmacology. Science 133, 613–621 (1961).
Genest, J.: Clinical states associated with abnormal aldosterone excretion. Canad. med. Ass. J. 77, 780–785 (1957).
—, P. Biron, M. Chrétien, R. Boucher, and E. Kiow: Blood angiotensin levels in normal subjects and hypertensive patients. J. clin. Invest. 41, 1360–1361 (1962).
—, —, M. E. Kiow, W. Nowaczynsri, R. Boucher, and M. Chrétien: Studies of the pathogenesis of human hypertension. The adrenal cortex and renal pressor mechanism. Ann. intern. Med. 55, 12–28 (1961a).
—, —, —, —, M. Chrétien, and R. Boucher: Adrenocortical hormones in human hypertension and their relation to angiotensin. Circulat. Res. 9, 775–791 (1961b).
—, R. Boucher, J. De Champlain, R. Veyrat, M. Chrétien, P. Biron, G. Tremblay, P. Roy, and P. Cartier: Studies on the rennin-angiotensin system in hypertensive patients. Canad. med. Ass. J. 90, 263–268 (1964a).
—, —, W. Nowaczynsri, E. Kiow, J. CDe hamplain, P. Biron, M. Chrétien, and J. Marcaurele: Studies on the relation of aldosterone and angiotensin to human hypertensive disease. In: E. E. Baulieu and P. Robel (eds.): Aldosterone. Oxford: Blackwell 1964b.
Gennari, F. J., and P. J. Mulrow: A mechanism for the reversal of experimental hypertension by hypothyroidism. Clin. Res. 10, 400 (1962).
Giacomelli, F.: Über Veränderungen der Nebennierenrinde nach Pinalektomie. Endokrinologie 42, 144–150 (1962).
Gilbert, G. J.: Subcommissural organic secretion in the dehydrated rat. Anat. Rec. 132, 563–568 (1958).
—: The subcommissural organ. Neurology (Minneap.) 10, 138–142 (1960).
Gill, J. R., Jr., D. T. Mason, and F. C. Bartter: Adrenergic nervous system in sodium metabolism: Effects of guanethidine and sodium retaining steroids in normal man. J. clin. Invest. 43, 177–184 (1964).
Gillenwater, J. Y., J. B. Scott, E. D. Frohlich, and F. J. Haddy: Acute chlorthiazide attenuation of the pressor responses to epinephrine, levarterenol and angiotensin in the perfused peripheral vascular bed. Clin. Res. 9, 233 (1961).
Ginn, H. E., and R. Cade: Aldosterone secretion in magnesium deficient rats. Physiologist 4, 40 (1961).
Giordano, G., and R. Balesteri: La glande épiphysaire dans la régulation de la biosyn-thése de l’aldostérone. Ann. Endocr. (Paris) 24, 331–347 (1963).
—, H. A. Samiy, J. Bloom, F. W. Haynes, and J. P. Merrill: Activity of some exzymes in experimental hypertension in the rabbit. Experientia (Basel) 17, 558–560 (1961).
Girerd, R. J., and C. L. Rassaert: Effect of various hormones upon the responsiveness of the hypophysectomized rat to DOCA implantation. Acta endocr. (Kbh.) 42, 337–347 (1963).
Giroud, C. J. P., M. Saffran, A. V. Schally, J. Stachenko, and E. H. Venning: Production of aldosterone by rat adrenal glands in vitro. Proc. Soc. exp. Biol. (N.Y.) 92, 855–859 (1956b).
—, J. Stachenko, and E. H. Venning: Secretion of aldosterone by the zona glomerulosa of rat adrenal glands incubated in vitro. Proc. Soc. exp. Biol. (N.Y.) 92, 154–158 (1956a).
Gláz, E., and K. Sugár: The effect of synthetic angiotensin II on synthesis of aldosterone by the adrenals. J. Endocr. 24, 299–302 (1962).
—, and —: Effect of heparin and heparinoids on the synthesis of aldosterone and corticosteroids by the rat adrenal gland. Endocrinology 74, 159–164 (1964).
Goding, J. R., and D. A. Denton: The responsiveness to sodium depletion in adrenalectomized sheep with parotid fistulae. Aust. J. exp. Biol. med. Sci. 37, 211–238 (1959).
Goeverts, P.: Experiments on the role of vasoconstrictor substances in the mechanism of renal hypertension in dogs. In: G. E. W. Wolstenholme and M. P. Cameron (eds.), Ciba Colloquium on Hypertension, p. 136–147. Boston: Little, Brown 1954.
—. and A. verniory: Vasoconstrictor properties of vena cava blood of dogs with acute and chronic renal hypertension. Acta med. scand., Suppl. 266, 419–428 (1952).
Gold, E. M., E. E. van Brunt, A. D. Daily, A. T. Boryczka, and W. F. Ganong: ACTH content of dog kidneys. Proc. Soc. exp. Biol. (N.Y.) 112, 626–629 (1963).
Goldberg, A. H., and L. S. Lilienfield: Evidence for the existence of a renal vasodilating factor. Circulation 28, 727–728 (1963).
Goldberg, L.I., R.H. Mcdonald Jr., and A.M. Zimmerman: Sodium diuresis produced by dopamine in patients with congestive heart failure. New Engl. J. Med. 269, 1060–1064 (1963).
Goldberg, M., and D. K. Mccurdy: Hyperaldosteronism and hypergranulation of the juxtaglomerular cells in renal hypertension: Metabolic studies. Ann. intern. Med. 59, 24–36 (1963).
Goldblatt, H., Y. J. Katz, H. A. Lewis, and E. Richardson: Studies on experimental hypertension. XX. The bioassay of renin. J. exp Med. 17, 309–313 (1943).
—, H. Lamfrom, and E. Haas: Physiological properties of renin and hypertensin. Amer. J. Physiol. 175, 75–83 (1953).
Goldfarb, B., and L. Ttobian: The inter-relation of hypoxia erythropoietin and the renal juxtaglomerular cell. Proc. Soc. exp. Biol. (N.Y.) 111, 510–511 (1962).
—, —: Effect of high oxygen concentration on erythropoietin and the renal juxtaglomerular cell. Proc. Soc. exp. Biol. (N.Y.) 113, 35–36 (1963).
Goldman, M. D., E. Ronzoni, and H. A. Schroeder: The response of the adrenal cortex of the rat to dietary salt restriction and replacement. Endocrinology 58, 57–61 (1956).
Gollan, F., E. Richardson, and H. Goldblatt: Hypertensin in the systemic blood of animals with experimental renal hypertension. J. exp Med. 88, 389–400 (1948).
Gombos, E. A., W. H. Hulet, P. Bopp, W. Goldring, D. S. Baldwin, and H. Chasis: Reactivity of renal and systemic circulation to vasoconstrictor agents in normotensive and hypertensive subjects. J. clin. Invest. 41, 203–217 (1962).
Gomez, A., S. W. Hoobler, and P. Blaquler: Effect of renal transplantation on adrenocortical hypertension. Physiologist 1, 28 (1958).
Ggomoll, A. W., and H. E. Schmid, Jr.: Urinary excretion of aldosterone in dogs with elevated plasma antirenin titers. Fed. Proc. 23, 301 (1964).
—, and T. R. Sherrod: Inhibitory action of acetyl strophanthidin on the secretion of aldosterone. Fed. Proc. 19, 152 (1960).
Goodkind, M. J., W.C. Ball, Jr., and J. O. Davis: Effect of chronic hemorrhage on urinary aldosterone-like activity and sodium excretion. Amer. J. Physiol. 189, 181–184 (1957).
Goodyer, A. V. N., A. S. Relman, F. D. Lawrason, and F. H. Epstein: Salt retention in cirrhosis of the liver. J. clin. Invest. 29, 973–981 (1950).
Goormaghtigh, N.: La fonction endocrine des arterioles rénales: Son role dans la pathogénie de l’hypertension artérielle. Louvain: Librairie R. Fonteyn 1944.
—: The renal arteriolar changes in the anuric crush syndrome. Amer. J. Path. 23, 513–529 (1947).
Gordon, D. B., and A. Nogueira: Increased vascular reactivity in experimental hypertension. Circulat. Res. 10, 269–273 (1962).
Gordon, E. S., J. J. Chart, D. Hagedorn, and E. G. Shipley: Mechanism of sodium retention in pre-eclamptic toxemia. Obstet. and Gynec. 4, 39–50 (1954).
Gornall, A. G., and C. Guilliam: Aldosterone I. Isolation from adrenocortical extract and a test for its identity. Canad. J. Biochem. 35, 71–78 (1957).
—, —, and A. E. D. Hall: Aldosterone secretion in various clinical states. J. clin. Endocr. 16, 950 (1956).
Gornel, D. L., R. C. Lancestremere, S. Papper, and L. M. Lowenstein: Acute changes in renal excretion of water and solute in patients with Laennec’s cirrhosis induced by the administration of the pressor amine metaraminol. J. clin. Invest. 41, 594–603 (1962).
Gowenlock, A. H., J. N. Mills, and S. Homas: Acute postural changes in aldosterone and electrolyte excretion in man. J. Physiol. (Lond.) 146, 133–141 (1959).
—, and O. Wrong: Hyperaldosteronism secondary to renal ischemia. Quart. J. Med. 31, 323–344 (1962).
Greene, M. A., A. J. Bolfax, M. Niv, and E. S. Soherr: Effects of vasoactive drugs on serum electrolytes in hypertensive and normotensive humans. Proc. Soc. exp. Biol. (N.Y.) 111, 423–427 (1962).
Greenough, W. B. III, E. H. Sonnenblick, V. Januszewicz, and J. H. Laragh: Correction of hyperaldosteronism and of massive fluid retention of unknown cause by sympathicomimetic agents. Amer. J. Med. 33, 603–614 (1962).
Greenway, C. V., and E. B. Verney: The effect of adrenocorticotrophic hormone on the secretion of corticosteroids by the isolated perfused adrenal gland of the dog. J. Physiol. (Lond.) 162, 183–192 (1962).
Greep, R. O., and H. W. Deane: Cytochemical evidence for the cessation of hormone production in the zona glomerulosa of the rat’s adrenal cortex after prolonged treatment with desoxycorticosterone acetate. Endocrinology 40, 417–425 (1947).
Grimson, K. S.: Role of the sympathetic nervous system in experimental neurogenic hypertension. Proc. Soc. exp. Biol. (N.Y.) 44, 219–221 (1940).
—: The sympathetic nervous system in neurogenic renal hypertension: experimental correlation and clinical consideration. Arch. Surg. 43, 284–305 (1941).
Grollman, A.: Antihypertensive and pressor agents of renal origin. Canad. med. Ass. J. 90, 299–302 (1964).
Grollman, A., and C. Rule: Experimentally induced hypertension in parabiotic rats. Amer. J. Physiol. 138, 587–592 (1943).
Gross, F.: Renin und Hypertensin; Physiologische oder pathologische Wirkstoffe. Klin. Wschr. 36, 693–706 (1958).
—: Adrenocortical function and renal pressor mechanism in experimental hypertension. In: K. D. Beck and P. T. Cottier (eds.), Essential hypertension, p. 92–111. Berlin-Göttingen-Heidelberg: Springer 1960.
—: Differentiation of effects mediated by aldosterone and rennin-angiotensin in experimental hypertension. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
—, O. Buschor, and H. Zeugin: Reduction of increased sensitivity to renin by cross circulation. Amer. J. Physiol. 202, 1095–1097 (1962).
—, O. Buschor, and P. Zeugin: Renin in the kidney of rats with aminonucleoside nephrosis. Amer. J. Physiol. 199, 1–4 (1960).
—, and W. D. Dettbarn: Water and salt loading in adrenalectomized dogs treated with cortexone, aldosterone and 9-α-fluorocortisol. Acta endocr. (Kbh.) 22, 335–370 (1956).
—, and P. Lichtlen: Experimental renal hypertension: Renin content of kidneys in intact and adrenalectomized rats given cortexone. Amer. J. Physiol. 195,543–548 (1958a).
—, and —: Pressor substance in kidneys of renal hypertensive rats with and without adrenals. Proc. Soc. exp. Biol. (N.Y.) 98, 431–345 (1958b).
—, P. Loustalot u. F. Susler: Die Bedeutung von Kochsalz für den Cortexon-Hochdruck der Ratte und den Gehalt der Nieren und presserischen Substanzen. Naunyn-Schmiedebergs Arch. exp Path. Pharmak. 229, 381–388 (1956).
—, G. Schaechtclin, H. Brunner, and G. Peter: The role of the renin angiotensin system in blood pressure regulation and kidney function. Canad. med. Ass. J. 90, 258–262 (1964).
—, u. F. Susler: Pressurische Substanzen in den Nieren experimentell hypertonischer Ratten. Naunyn-Schmiedebergs Arch. exp Path. Pharmak. 229, 374–380 (1956).
—, u. —: Der Einfiuß der Nebennieren auf die blutdrucksteigernde Wirkung von Renin und auf pressorische Substanzen in den Nieren. Naunyn-Schmiedebergs Arch. exp Path. Pharmak. 203, 274–283 (1957).
—, and H. Turrian: Pharmacology of hypertensin and synthetic analogues. In: M. Schachter (ed.), Polypeptides which affect smooth muscles, p. 137–151. London: Pergamon 1960.
Haas, E., and H. Goldblatt: Renin content of kidneys in experimental renal and human hypertension. Amer. J. Physiol. 197, 1103–1106 (1959).
—, — and E. C.G ipson: A study of enzymatic and antigenic properties of renin. J. Immunol. 91, 170–178 (1963).
—, H. Lamfrom, and H. Goldblatt: A simple method for the extraction and partial purification of renin. Arch. Biochem. 48, 256–260 (1954).
Halasz, B.: Der zeitliche Ablauf von Veränderungen des Kernvolumens in der Nebennierenrinde. Acta morph. Acad. Sci. hung. 7, 193–198 (1958).
Hamilton, A. S., and D. A. Collins: Role of the kidney in the maintenance of arterial blood pressure in hemorrhage. Amer. J. med. Sci. 202, 914 (1941).
Hamilton, J. G., and A. Grollman: The preparation of renal extracts effective in reducing blood pressure in experimental hypertension. J. Biol. Chem. 233, 528–529 (1958).
Hartroft, P. M.: Juxtaglomerular cells. Circulat. Res. 12, 525–533 (1963).
—, and R. Edelman: Renal juxtaglomerular cells in sodium deficiency. In.: J. Moyer and M. Fuchs (eds.), Edema: Mechanisms and management, p. 63–68. Philadelphia: Saunders 1960.
—., and W. S. Hartroft: Studies on renal juxtaglomerular cells. I. Variations produced by sodium chloride and desoxycorticosterone acetate. J. exp Med. 97, 415–428 (1953).
—., and —: Studies on renal juxtaglomerular cells. II. Correlation of the degree of granulation of juxtaglomerular cells with width of the zona glomerulosa of the adrenal cortex. J. exp Med. 102, 205–212 (1955).
—., and S. D. Hathaway: Effect of pitressin on juxtaglomerular cells and zona glomerulosa of sodium deficient rats. Fed. Proc. 23, 445 (1964).
Hartroft, W. S., and P. M. Hartroft: New approaches in the study of cardiovascular disease: aldosterone, renin, hypertension and juxtaglomerular cells. Fed. Proc. 20, 845–854 (1961).
Hatt, P. Y., Y. Allalre, P. Berjál, J. Chauveau, M. Dvojakovic, H. Kernec, J. Grossetête et H. Guillemot: L’appareil juxtaglomérulaire dans l’hypertension arterielle expérimentale. J. Urol. Nephrol. 68, 544–549 (1962).
Hawthorne, E. W., and M. Gaspar: Antihypertensive effect of hypophysectomy in dogs with hypertension following bilateral carotid sinus constriction. Circulat. Res. 7, 705–708 (1959).
Hawthorne, E. W., S. L. C. Perry, and W. G. Pogue: Development of experimental renal hypertension in the dog following reduction of renal arterial pulse pressure without reducing mean pressure, Amer. J. Physiol. 174, 393–396 (1953).
Hayes, M. A., and I. S. Goldenberg: Renal effects of anesthesia and operation mediated by endocrines. Anesthesiology 24, 487–499 (1963).
Haynes, F. W., L. Dexter, and R. S. Seibel: Renin content of renal venous blood of normal and hypertensive patients at rest. Amer. J. Physiol. 150, 198–201 (1947).
— P. H. Forsham, and D. M. Hume: Effects of ACTH, cortisone, desoxycorticosterone and epinephrine plasma hypertensinogen and renin concentration of dogs. Amer. J. Physiol. 172, 265–275 (1953).
Haynes, R. C., Jr.: The activation of adrenal phosphorylase by the adrenocorticotrophic hormone. J. Biol. Chem. 233, 1220–1222 (1958).
Hebb, C., and R. H. Nimmo-Smith: Partition of potassium between the isolated lung of dog and its perfusate with particular reference to the action of epinephrine. J. Physiol. (Lond.) 105, 1–15 (1946).
Helmer, O. M.: Studies on renin antibodies. Circulation 17, 648–652 (1958).
— Presence of renin in plasma of patients with arterial hypertension. Circulation 25, 169–173 (1962).
— Renin activity in blood from patients with hypertension. Canad. med. Ass. J. 90, 221–225 (1964).
— and W. E. Judson: The quantitative determinations of renin in the plasma of patients with arterial hypertension. Circulation 27, 1050–1060 (1963).
Heni, F., P. Gruner, u. H. Mast: Untersuchungen über Eigenleistung der Nebennierenrinde hypophysektomierter Ratten. Acta endocr. (Kbh.) 11, 229–244 (1952).
Hess, R., and F. Gross: Glucose-6-phosphate dehydrogenase and renin in kidney of hypertensive and adrenalectomized rats. Amer. J. Physiol. 197, 869–872 (1959).
— and A. G. E. Pearse: The significance of renal glucose-6-phosphate dehydrogenase in experimental hypertension in the rat (a histochemical study). Brit. J. exp. Path. 40, 243–249 (1959).
— — Mitochondrial α-glycerophosphate dehydrogenase activity of juxtaglomerular cells in experimental hypertension and adrenal insufficiency. Proc. Soc. exp. Biol. (N.Y.) 106, 895–898 (1961).
Hickler, R. B., D. P. Lauler, C. A. Saravis, A. I. Vagnucci, G. Steiner, and G. W. Thorn: Vasodepressor lipid from the renal medullar. Canad. med. Ass. J. 90, 280–287 (1964).
— —, and G. W. Thorn: Plasma angiotensin activity in patients with hypertension and edema. J. clin. Invest. 42, 635–648 (1963a).
— C. H. Saravis, S. F. Mowbray, D. P. Lauler, A. I. Vagnucci, and G. W. Thorn: Renal medullary vasopressor factor. J. clin. Invest. 42, 942 (1963b).
Higginbotham, R. D., and T. F. Dougherty: Potentiation of polymyxin-B toxicity by ACTH. Proc. Soc. exp. Biol. (N.Y.) 96, 464–470 (1957).
Higgins, J. T., Jr., and J. O. Davis: Hypersecretion of aldosterone in dogs with chronic aortic caval fistula and heart failure. Fed. Proc. 22, 210 (1963).
— and J. Urquhart: Demonstration by pressor and steroidogenic assays of increased renin in lymph of dogs with secondary hyperaldosteronism. Circulat. Res. 14, 218–227 (1964).
Hill, M., M. Pospišil, and K. Dvořák: On the participation of the zona glomerulosa in the adrenal response to stress. Experientia (Basel) 14, 419–421 (1958).
Hill, S.R., Jr., W. G. Hood, Jr., T. A. Farmer, Jr., and J. F. Burnum: Ideopathic edema. New EngI. J. Med. 263, 1342–1345 (1960).
— J. F. Nickerson, S. B. Chenault, J. H. Macneil, W. R. Starnes, and M. C. Gautney: Studies in man on hyper- and hypo-aldosteronism. Arch. intern. Med. 104, 982–994 (1959).
Hirashima, K., and F. Takaku: Experimental studies on erythropoietin: II. The relation between juxtaglomerular cells and erythropoietin. Blood 20, 1–8 (1962).
Hökfelt, B., and B. Sranse: Effect of aldosterone in a case of hypoaldosteronism. Acta endocr. (Kbh.) 33, 511–519 (1960).
Hoff, E. C., J. F. Kell, Jr., and M. N. Carroll, Jr.: Effects of cortical stimulation and lesions on cardiovascular function. Physiol. Rev. 43, 68–114 (1963).
— — N. Hastings, D. M. Sholes, and E. H. Gray: Vasomotor cellular and functional changes produced in kidney by brain stimulation. J. Neurophysiol. 14, 317–332 (1951).
Holmes, W. N., J. G. Phillips, and D. G. Butler: The effect of adrenocortical steroids on the renal and extrarenal responses of the domestic duck (Anas platyrhynchus) after hypertonic saline loading. Endocrinology 69, 483–495 (1961).
Holzbauer, M.: Aldosterone secretion during operative stress in relation to release of ACTH. J. Physiol. (Lond.) 168, 40P (1963).
Holzbauer, M., and M. Vogt: Rapid changes in aldosterone secretion by the adrenal of the dog. 21st Int. Physiology Congress 1959a, p. 128.
— — Observations on the control of the secretion of aldosterone. J. Physiol. (Lond.) 148, 13P–14P (1959b).
— — The effect of anoxia produced by removal of red cells on aldosterone secretion from the dog adrenal. J. Physiol. (Lond.) 153, 55P (1960a).
— — Corticosteroids in plasma and cells of adrenal venous blood. J. Physiol. (Lond.) 157, 137–156 (1960b).
— — Splanchnotomy and aldosterone secretion. J. Physiol. (Lond.) 165, 21P (1963).
Hoobler, S., J. Schroeder, P. Blaqmer, and V. Demerjian: Further studies on the mechanism whereby nephrectomy augments the pressor response to renin. Canad. med. Ass. J. 90, 227–231 (1964).
Houck, C. R.: Alterations in renal hemodynamics and function during the intravenous injection of epinephrine in the dog. Amer. J. Physiol. 166, 649–657 (1951a).
— Alterations in renal hemodynamics and function in separate kidneys during stimulation of renal artery nerves in dogs. Amer. J. Physiol. 167, 523–530 (1951b).
Houdas, Y., et J. C. Favarel-Garrigues: La régulation physiologique de la sécrétion de l’aldostérone: problémes actuels. Path. et Biol. 11, 779–788 (1963).
Howard, J. E.: Hypertension as related to renal ischemia. George Brown Memorial Lecture. Circulation 24, 657–665 (1964).
Howell, D. S., J. O. Davis, and G. L. Lacquer: Effect of hypophysectomy on electrolyte excretion in dogs with ascites produced by thoracic inferior vena cava constriction. Circulat. Res. 3, 264–273 (1955).
Hudson, J. B., A. V. Chabanian, and A. S. Relman: Hypoaldosteronism: a clinical study of a patient with an isolated adrenal mineralocorticoid deficiency, resulting in hyperkalemia and Stokes-Adams attacks. New Engl. J. Med. 257, 529–536 (1957).
Huidobro, F., and E. Braun-Menéndez: The secretion of renin by the intact kidney. Amer. J. Physiol. 127, 47–55 (1942).
Huidobro, H. V., and A. C. Paladini: Potentiation of angiotensin action on smooth muscle by alkaline pH. Experientia (Basel) 19, 572–573 (1963).
Hume, D. M.: Hypothalamic localization of the control of various endocrine secretions. In: H. H. Jasper, L. D. Procter, R. S. Knighton, W. C. Noshay, and R. T. Castello (eds.), Reticular formation of the brain, p. 111–142. Boston: Little, Brown 1958a.
— The method of hypothalamic regulation of pituitary and adrenal secretion in response to trauma. In: S. Curri and L. Martini (eds.), Pathophysiologica diencephalica, p. 217–228. Wien: Springer 1958b.
— C. C. Bell, and F. Bartter: Direct measurement of adrenal secretion during operative trauma and convalescence. Surgery 52, 174–187 (1962).
—, and D. H. Nelson: Adrenocortical function in surgical shock. Surg. Forum 5, 568–575 (1955).
Hungerford, G. F.: The effect of age in determining the adrenal response to a low sodium diet. Anat. Rec. 133, 394–395 (1959).
—, and H. M. Panagiotis: Response of pineal lipid to hormone imbalances. Endocrinology 71, 936–942 (1962).
Ikos, D., R. Luft, and C. A. Gemzell: The effect of human growth hormone in man. Acta endocr. (Kbh.) 32, 341–361 (1959).
Ingle, D. J., G. M. Higgins, and E. C. Kendall: Atrophy of the adrenal cortex in the rat produced by administration of large amounts of cortin. Anat. Rec. 71, 363–372 (1938).
Itskovitz, H. D., E. A. Hildreth, A. M. Sellers, and W. S. Blakemore: The granularity of the juxtaglomerular cells in human hypertension. Ann. intern. Med. 59, 8–22 (1963).
Jablons, B., M. Kolak, A. H. W. Wolfson, and M. Lion: Inhibitory effect of kidney derived vasodilator, tubulin, on pressor response to aldosterone in humans. Circulation 26, 736–737 (1962).
Jacobs, D. R., J. van der Poll, L. Gabrilove, and L. J. Soffer: 17.Hydroxyprogesterone-a salt-losing steroid: relation to congenital adrenal hyperplasia. J. clin. Endocr. 21, 909–922 (1961).
— and J. B. Posner: Isolated hypoaldosteronism manifested by periodic paralysis, hyper. kalemia and salt-losing tendency. Clin. Res. 10, 250 (1962).
Jaoobson, L. O.: Erythropoietin and the regulation of the red blood cell formation. Physiol. Physicians 1, No 8 (1963).
—, and M. Doyle: Erythropoiesis. New York: Grune & Stratton 1963.
Jessiliman, A. G., D. D. Matson, and F. D. Moore: Hypophysectomy in the treatment of breast cancer. New Engl. J. Med. 261, 1199–1207 (1959).
Johnson, B. B.: Bioassay of adrenal cortical steroids on the basis of electrolyte excretion by rats: effects of 11-desoxy- and 11-oxy-steroids. Endocrinology 54, 196–208 (1954).
Johnson, B. B., A. H. Lieberman, and P. J. Mulrow: Aldosterone excretion in normal subjects depleted of sodium and potassium. J. clin. Invest. 36, 757–766 (1957).
Johnson, H. C., and K. M. Browne: Cerebral cortical ablations in dogs with chronic renal hypertension. J. Neurophysiol. 17, 183–188 (1954).
Johnston, C. I., and A. D. Jose: Reduced vascular response to angiotensin II in secondary hyperaldosteronism. J. clin. Invest. 42, 1411–1420 (1963).
Jones, F. M., R. Lloyd-Jones, A. Riondel, J. F. Tait, S. A. S. TAit, R. D. Bulbrook, and F. C. Greenwood: Aldosterone secretion and metabolism in normal men and women and in pregnancy. Acta endocr. (Kbh.) 30, 321–342 (1959).
Jones, N. F., and M. A. Barraclough: Angiotensin. Response of the kidneys in unilateral renal artery stenosis. Lancet 1962 I, 454–457.
— —, and I. H. Mills: The mechanism of increased sodium excretion during water loading with 2.5% dextrose and vasopressin. Clin. Sci. 25, 449–457 (1963).
Jouan, P.: Action de l’épiphyse sur la sécrétion in vitro de l’aldostérone par les surrénales du rat. C. R. Acad. Sci. (Paris) 204, 2680–2682 (1962a).
— Action de l’adrénoglomérulotrophine sur la corticoidegenése in vitro chez le rat. C. R. Soc. Biol. (Paris) 156, 1567–1569 (1962b).
— Epiphyse, 5-hydroxytryptamine et corticoidogenése in vitro. Ann. Endocr. (Paris) 24, 365–370 (1963).
Judson, W. E.: Pressor activity of dialyzed plasma of patients with primary and secondary (renal) hypertension. Amer. J. Cardiol. 9, 710–715 (1962).
Jungmann, P., u. E. Meyer: Experimentelle Untersuchungen über die Abhängigkeit der Nierenfunktion vom Nervensystem. Naunyn-Schmiedebergs. Arch. exp. Path. Pharmak. 73, 49–80 (1913).
Kahn, J.R., L. T. Skeggs, Jr., N. P. Shumway, and P. E. Wisenbaugh: The assay of hypertensin from the arterial blood of normotensive and hypertensive human beings. J. exp. Med. 95, 523–529 (1952).
Kalant, N., D. das Gupta, R. Despointes, and C. J. P. Giroud: Mechanism of edema in experimental nephrosis. Amer. J. Physiol. 202, 91–96 (1962).
Kaplan, N. M.: Comparison of aldosterone secretion and excretion measurements. Clin. Res. 11, 221 (1963).
— and F. C. Bartter: The effect of ACTH, renin, angiotensin II and various precursors on biosynthesis of aldosterone by adrenal slices. J. clin. Invest. 41, 715–724 (1962).
— and J. G. Silah: The effect of angiotensin II on the blood pressure in humans with hypertensive disease. J. clin. Invest. 43, 659–669 (1964).
Katz, Y. J.: Angiotensin and the kidney. Lancet 1961 I, 1006.
— S. Bernick, P. R. Patek, R. de Hoyos, and R. S. Moore: The inter-relation of angiotensin and aldosterone on kidney renin. Physiologist 5, 165 (1962a).
—, and A. T. K. Cockett: Elevation of inferior vena cava pressure and thoracic lymph and urine flow. Circulat. Res. 7, 118–122 (1959).
— R. S. Moore, A. M. Velasquez, and I. T. Tamersaltis: Angiotensin pressor inhibition by aldosterone in the rabbit. Science 141, 725–726 (1963).
— P. R. Patek, and S. Bernick: Effect of angiotensin on juxtaglomerular cells and vessels of the kidney. Circulat. Res. 11, 955–960 (1962b).
Keeler, R., and H. Schnieden: Investigation of the mechanism of diuresis produced in the rat by an intravenous infusion of isotonic solution of sodium chloride. Amer. J. Physiol. 195, 137–141 (1958).
Keller, A., L. E. Piotti et J. D. Romani: Nouvelles preuves de l’activité adréno-glomérulotrope de l’extrait epiphysaire. Ann. Endocr. (Paris) 22, 82–86 (1961).
Kelly, D. E.: Pineal organs: photoreception, secretion and development. Amer. Scientist 50, 597–625 (1962).
Kempner, W.: Treatment of hypertensive vascular disease with rice diet. Amer. J. Med. 4, 545–554 (1948).
Kennedy, A., D. Kilshaw, N. C. R. W. Reid, and W. H. Taylor: Pineal enlargement with hypernatremia, hypokalemic alkalosis and thyrotoxicosis. Brit. med. J. 1962 II, 641–644.
Khairallah, P. A., F. M. Bumpus, I. H. Page, and R. R. Smeby: Unitage and suggested designation of angiotensin activity. Nature (Lond.) 196, 1059–1061 (1962).
— — — — Angiotensinase with a high degree of specificity in plasma and red cells. Science 140, 672–674 (1963a).
— I. H. Page, F. M. Bumpus, and R. R. Smeby: Angiotensin II: Its metabolic fate. Science 138, 523–525 (1963b).
Kilburn, K. H., and H. O. Sieker: Effect of continuous positive and negative pressure breathing on intrathoracic hemodynamics in man. Circulation 18, 741 (1958).
Kitay, J. I., and M. D. Altschule: The pineal gland. Cambridge (Mass.): Harvard University Press 1954.
Kittinger, G. W., B. C. Wexler, and B. F. Miller: Effect of aldosterone antagonism on in vitro production of aldosterone and corticosterone in rats. Proc. Soc. exp. Biol. (N.Y.) 105, 394–395 (1960).
Klein, R., P. Taylor, C. Papadatos, Z. Laron, D. Keele, J. Fortunato, C. Byers, and C. Billings: Sodium losing material in human urine. Proc. Soc. exp. Biol. (N.Y.) 98, 863–866 (1958).
Kliman, B., and R. E. Peterson: Double isotope derivative assay of aldosterone in biological extracts. J. Biol. Chem. 235, 1639–1648 (1960).
— J. Rahill, and F. C. Bartter: Alterations in aldosterone secretion during sustained, maximal ACTH treatment. Endocr. Soc. Abstract 74 (1961).
Knigge, K. M.: Response of the hamster’s adrenal cortex to desoxycorticosterone acetate, with observations on the kidney, thyroid and hypophysis. Endocrinology 55, 731–744 (1954).
Knobil, E., and R. O. Greep: Serum electrolytes in the hypophysectomized rhesus monkey. Endocrinology 62, 61–63 (1958).
— and J. Hotchkiss: Growth hormone. Ann. Rev. Physiol. 26, 47–74 (1964).
— A. Morse, F. G. Hofmann, and R. O. Greep: A histologic and histochemical study of hypophyseal-adrenocortical relationships in the rhesus monkey. Acta endocr. (Kbh.) 17, 229–238 (1954).
Kohlstaedt, K. G., and I. H. Page: The liberation of renin by perfusion of kidneys following reduction in pulse pressure. J. exp Med. 72, 201–216 (1940).
Koletsky, S., and W. H. Prichard: Vasopressor material in experimental hypertension. Circulat. Res. 13, 552–556 (1963).
Kolff, W. J.: Discussion in Circulation 17, 676–679 (1958).
Kolman, S. N.: Improvement of hypertensive and uremic states in dogs when subjected to chronic lymphatic shunts. Physiologist 5, 169 (1962).
Kornel, L.: Kidney, adrenal cortex and hypertension. Arch. intern. Med. 103, 820–831 (1959).
Korner, P. I.: Effects of low oxygen and of carbon monoxide on the renal circulation in unanesthetized rabbits. Circulat. Res. 12, 361–374 (1963).
Kottke, F. J., W. G. Kubicek, and M. B. Visscher: The production of arterial hypertension by chronic renal artery nerve stimulation. Amer. J. Physiol. 145, 38–47 (1945).
Kovách, A. G. B., M. Földi, N. Papp, D. S. Róheim, and E. Koltay: Cerebral regulation of sodium excretion. Lancet 1959 I, 338–339.
Kovács, K., M. A. Dávid, and P. Weisz: Aldosteronotrophic and corticosteronotrophic substances in normal human brain. Med. exp. 3, 113–116 (1960).
Kramer, A. A., and Y. A. Serebrovskaya: Renin activity in the kidneys in vascular hypertension and in symptomatic renal hypertension [in Russian]. Ter. Arkh. 34, 14–17 (1962).
Kremen, S. H., and G. E. Wakerlin: Renin and antirenin in the treatment of long-term experimental renal hypertension in the dog. Proc. Soc. exp. Biol. (N.Y.) 90, 99–101 (1955).
Krieger, D. T., A. Saite, and H. P. Krieger: Aldosterone excretion in disease of the pretectum. Lancet 1961 II, 567–570.
Kubicek, W. G., F. J. Kottke, D. J. Laker, and M. B. Visscher: Renal function during arterial hypertension produced by chronic splanchnic nerve stimulation in the dog. Amer. J. Physiol. 174, 397–400 (1953).
—, and A. P. Thal: Diverting renal and adrenal vein blood into liver and renal hypertension in dogs. Amer. J. Physiol. 205, 1275–1278 (1963).
Kukuchi, S.: Hypertension and aldosterone. II. Urinary aldosterone in human arterial hypertension [in Japanese]. Folia endocr. jap. 36, 1371–1378 (1960).
Kumar, D., L. A. W. Feltram, and A. G. Gornall: Aldosterone excretion and tissue electrolytes in normal pregnancy and pre-eclampsia. Lancet 1959 I, 541–545.
Laidlaw, J. C., J. L. Ruse, and A. G. Gornall: The influence of estrogen and progesterone on aldosterone excretion. J. clin. Endocr. 22, 161–171 (1962).
— E. R. Yendt, C. E. Bird, and A. G. Gornall: Hypertension due to renal artery occlusion simulating primary aldosteronism. Canad. med. Ass. J. 90, 321–325 (1964).
—, and A. G. Gornall: Hypertension caused by renal artery occlusion simulating primary aldosteronism. Metabolism 9, 612–623 (1960).
Lambrew, C. T., S. T. Carver, R. E. Peterson, and M. Horwith: Hypoaldosteronism as a cause of hyperkalemia and syncopal attacks in a patient with complete heart block. Amer. J. Med. 31, 81–85 (1961).
Lamfrom, H., E. Haas, and H. Goldblatt: Studies on antirenin. Amer. J. Physiol. 177, 55–64 (1959).
Lamson, E. T., F. Elmadjian, J. M. Hope, G. Pincus, and D. Jorjorian: Aldosterone excretion in normal, schizophrenic and psychoneurotic subjects. J. clin. Endocr. 16, 954 (1956).
Landau, R. L., and K. Lugibihl: Inhibition of the sodium retaining influence of aldosterone by progesterone. J. clin. Endocr. 18, 1237–1245 (1958).
Lane, N., and R. C. de Bodo: Generalized adrenal cortical atrophy in hypophysectomized dogs and correlated functional studies. Amer. J. Physiol. 168, 1–19 (1952).
Langford, H. G.: Tubular action of angiotensin. Canad. med. Ass. J. 90, 332–333 (1964).
—, and F. Allison, Jr.: Arteriolar changes in renin tachyphylaxis. Amer. J. Physiol. 200, 130–132 (1961).
— L. H. Day, T. Conner, and J. E. Howard: A pressor substance, probably angiotensin, found in renal venous blood. Clin. Res. 9, 57 (1961).
— and M. E. Fallis: Tubular effect of angiotensin. Circulation 28, 754 (1963).
— J. Mayfield, and O. Irby: Direct pressor role of ischemic kidney in renal hypertension. Clin. Res. 10, 251 (1962).
— and G. W. Pickering: The diuretic action of angiotensin. Clin. Res. 11, 68 (1963).
Lanthier, A., and C. E. Grignon: Clinical studies on the control of sodium and water metabolism in panhypopituitarism. Amer. J. med. Sci. 236, 353–361 (1958).
Laragh, J. H.: The role of aldosterone in man. J. Amer. med. Ass. 174, 293–295 (1960).
— Relation of aldosterone secretion to hypertensive vascular disease. Circulat. Res. 9, 792–802 (1961).
— Interrelationship between angiotensin, norepinephrine, epinephrine, aldosterone secretion and electrolyte metabolism in man. Circulation 25, 203–211 (1962a).
— Hormones and the pathogenesis of congestive heart failure: vasopressin, aldosterone and angiotensin II. Circulation 24, 1015–1032 (1962b).
— M. Angers, W. G. Kelly, and S. Lieberman: Hypotensive agents and pressor substances. J. Amer. med. Ass. 174, 234–240 (1960a).
— P. J. Cannon, and R. P. Ames: Aldosterone secretion and various forms of hypertensive vascular disease. Ann. intern. Med. 59, 117–119 (1963a).
— —, and R. P. Ames: Aldosteronism: Factors controlling secretion of the hormone. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964a.
— — — Interaction between aldosterone secretion, sodium and potassium balance and angiotensin activity in man: studies in hypertension and cirrhosis. Canad. med. Ass. J. 90.248–256 (1964b).
— — C. J. Bentzel, A. M. Sicinski, and J. I. Meltzer: Angiotensin II, norepinephrine and renal transport of electrolytes and water in normal man and in cirrhosis with ascites. J. clin. Invest. 42, 1179–1192 (1963b).
—, and H. C. Stoerk: A study of the mechanism of secretion of the sodium-retaining hormone (Aldosterone). J. clin. Invest. 36, 383–392 (1957).
— S. Ulick, B. Januszewicz, Q. B. Deming, W. G. Kelly, and S. Lieberman: Aldosterone secretion and primary and malignant hypertension J. clin. Invest. 39, 1091–1106 (1960b).
— — — W. G. Kelly, and S. Lieberman: Electrolyte metabolism and aldosterone secretion in benign and malignant hypertension. Ann. intern. Med. 53, 259–272 (1960c).
— —, and S. Lieberman: Rate of secretion of aldosterone by the adrenal cortex in normal man and in patients with heart failure, nephrosis and cirrhosis. Circulation 28, 745–746 (1958).
Lauler, D. P., and R. B. Hickler: Angiotensin II influence in adrenalectomized dogs. Clin. Res. 10, 251 (1962).
— A. I. Vagnucci, R. B. Hickler, and G. W. Thorn: Clinical features of sodium retention induced by antihypertensive therapy. Circulation 28, 754–755 (1963).
Laumas, K. R., J. F. Tait, and S. A. S. Tait: The validity of the calculation of secretion rates from the specific activity of a urinary metabolite. Acta endocr. (Kbh.) 36, 265–280 (1961a).
— — — Further considerations on the calculations of secretion rates. A correction. Acta endocr. (Kbh.) 36, 265–280 (1961a).
Laverty, R.: A nervously-mediated action of angiotensin in anesthetized rats. J. Pharm. Pharmacol. 15, 63–68 (1963).
— and F. H. Smirk: Observations on the pathogenesis of spontaneous inherited hypertension and constricted renal artery hypertension in rats. Circulat. Res. 9, 455––463 (1961).
Leaf, A.: The clinical and physiological significance of the serum sodium concentration. New Engl. J. Med. 267, 24–30, 77–83 (1962).
Le Brie, S. J., and H. S. Mayerson: Influence of elevated venous pressure on flow and composition of renal lymph. Amer. J. Physiol. 198, 1037–1040 (1960).
Ledsome, J. R., R. J. Linden, and W. J. O’Conner: The mechanisms by which distension of the left atrium produces diuresis in anesthetized dogs. J. Physiol. (Lond.) 159, 87–100 (1961).
Lee, J. B., R. B. Hickler, C. A. Saravis, and G. W. Thorn: Sustained depressor effect of renal medullary extract in the normotensive rat. Circulat. Res. 13, 359–366 (1963).
Lee, J. B., D. H. Nelson, and G. W. Thorn: The cyclical pattern of renal excretion during the adaptation of normal subjects to desoxycorticosterone induced sodium retention. J. clin. Endocr. 21, 1426–1439 (1961).
Lee, T. C., E. E. Van Brunt, E. G. Biglieri, and W. F. Ganong: Aldosterone secretion in dogs treated with hog renin. Fed. Proc. 23, 301 (1964).
Lemaire, R., et A. Mazer: Influence du séjour en climat désertique sur le taux de l’aldostérone urinaire. C. R. Soc. Biol. (Paris) 115, 583–584 (1961).
Lentz, K. E., L. T. Skeggs, K. R. Woods, J. R. Kahn, and N. P. Shumway: The amino acid composition of hypertensin II and its biochemical relation to hypertensin I. J. exp Med. 104, 183–192 (1956).
Lever, A. F., and W. S. Peart: Renin and angiotensin-like activity in renal lymph. J. Physiol. (Lond.) 160,548–563 (1962).
— and M. Tree: The estimation of renin in rabbit plasma. J. Physiol. (Lond.) 166, 26P–27P (1963).
Levinsky, N. G., and R. C. Lalone: The mechanism of sodium diuresis after saline infusion in the dog. J. clin. Invest. 42, 1261–1276 (1963).
Levitin, H., W. B. Lehmann, G. Pigeon, Y. Warren, and I. S. Goldenberg: The effect of anesthesia and adrenalectomy on the renal response to angiotensin. J. clin. Invest. 42, 951 (1963).
Lewy, F. H., and F. K. Gassmann: Experiments on the hypothalamic nuclei in the regulation of chloride and sugar metabolism. Amer. J. Physiol. 112, 504–510 (1935).
Liddle, G. W., F. C. Bartter, L. E. Duncan, J. K. Barber, and C. Delea: Mechanisms regulating aldosterone production in man. J. clin. Invest. 34, 949–950 (1955b).
— J. Cornfield, A. G. T. Casper, and F. C. Bartter: The physiological basis for a method of assaying aldosterone in extracts of human urine. J. clin. Invest. 34, 1410–1416 (1955a).
— D. Island, E. M. Lance, and A. P. Harris: Alteration of adrenal steroid patterns in man resulting from treatment with a chemical inhibitor of 11-hydroxylation. J. clin. Endocr. 18, 906–912 (1958).
— —, and C. Meader: Normal and abnormal regulation of corticotropin secretion in man. Recent Progr. Hormone Res. 18, 125–166 (1962).
Lieberman, A. H.: Current status of aldosterone in the etiology of edema. Arch. intern. Med. 102, 990–997 (1958).
—, and J. A. Leutscher, Jr.: Stimulation of adrenocortical secretions after air encephalography. J. clin. Invest. 36, 911 (1957).
—, —, Some effects of abnormalities of pituitary, adrenal or thyroid function on excretion of aldosterone and the response to corticotropin or sodium deprivation. J. clin. Endocr. 20, 1004–1016 (1960).
Little, B., J. Bougas, J. F. Tait, and S. A. S. Tait: The hepatic extraction of aldosterone 7-H3 and progesterone 7-H3. Endocr. Soc. Abstracts, 2–3 (1963).
Llaurado, J. G.: Increased secretion of aldosterone immediately after operation. Lancet 1955 I 1295–1298.
— Aldosterone secretion following hypophysectomy in man: relation to urinary sodium/potassium ratio. Metabolism 6, 556–563 (1957).
Lostroh, A. J.: Synergistic effect of somatotrophin with corticotrophin on the adrenal of hypophysectomized rats. Proc. Soc. exp. Biol. (N.Y.) 97, 828–832 (1958).
—, and C. H. Li: Effects of growth hormone and thyroxine on body weight of hypophysectomized C3H mice. Endocrinology 62, 484–492 (1958).
—, and P. Woodward: Changes in the adrenal of the hypophysectomized C3H mouse with α-corticotrophin and growth hormone. Endocrinology 62, 484–492 (1958).
Loyke, H.: Angiotensinogen effect in CCI4-treated experimental hypertension. Clin. Res. 11, 170 (1963).
Lucis, O. J., I. Dyrenfurth, J. C. Beck, and E. H. Venning: In vitro secretion of corticosteroids by rat adrenal. Fed. Proc. 18, 277 (1959).
— —, and E. H. Venning: Effect of various preparations of pituitary and diencephalon on the in vitro secretion of aldosterone and corticosterone by the rat adrenal. Canad. J. Biochem. 39, 901–903 (1961).
—, and E. H. Venning: In vitro and in vivo effect of growth hormone on aldosterone secretion. Canad. J. Biochem. 38, 1069–1075 (1960).
Luetscher, J. A., Jr.: Aldosterone. Advanc. intern. Med. 8, 155–203 (1956a).
— Studies of aldosterone in relation to water and electrolyte balance in man. Recent Progr. Hormone Res. 12, 175–184 (1956b).
— Idiopathic edema with hyperaldosteronuria. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
— C. A. Camargo, A. P. Cohn, A. J. Dowdy, and A. M. Callaghan: Observations on metabolism of aldosterone in man. Ann. intern. Med. 59, 1–7 (1963a).
Luetscher, J.A., Jr., A. P. Cohn, C. A. Camargo, A. J. Dowdy, and A. M. Callaghan: Aldosterone secretion and metabolism in hyperthyroidism and myxedema. J. clin. Endocr. 23, 873–880 (1963b).
— A. J. Dowdy, A. M. Callaghan, and A. P. Cohn: Studies of secretion and metabolism of aldosterone and cortisol. Trans. Ass. Amer. Phycns 75, 293–300 (1962).
— B. B. Johnson, A. Dowdy, J. Hanery, W. Lew, and L. J. Poo: Observations on the sodium-retaining corticoid (aldosterone) in the urine of children and adults in relation to sodium balance and edema. J. clin. Invest. 33, 1441–1446 (1954).
—, and A. H. Lieberman: Aldosterone. Arch. intern. Med. 102, 314–330 (1958).
Lurie, A. O., and W. P. U. Jackson: Aldosteronuria and the edema of kwashiorkor. Amer. J. clin. Nutr. 11, 115–126 (1962).
Maccmi, I A.: In vitro action of mammalian adrenocorticotropin and 5-hydroxytryptamine on adrenocortical secretion in the turtle, snake and bullfrog. Amer. Zool. 3, 548–556 (1963).
Mach, R. S., J. Fabre, A. F. MüLLER, and R. Neher: Oedemes par rétention de chlorure de sodium avec hyperaldosteronurie. Schweiz. med. Wschr. 85, 1229–1234 (1955).
Machado, A. B. M., and C. R. da Silva: Pineal body and urinary sodium excretion in the rat. Experientia (Basel) 19, 264–265 (1963).
MacLean, J. P., M. B. Lipsett, M. C. Li, C. D. West, and O. H. Pearson: Regulation of salt metabolism after hypophysectomy in man. J. clin. Endocr. 17, 346–355 (1957).
Mandel, M. J., and L. A. Sapirstein: Effect of angiotensin infusion on regional blood flow and regional vascular resistance in the rat. Circulat. Res. 10, 807–816 (1962).
Marieb, N. J., and P. J. Mulrow: The response of aldosterone secretion to angiotensin in the rat. Fed. Proc. 23, 300 (1964).
Markley, K., M. Bocanegra, G. Morales, and M. Chiapport: Oral sodium loading in normal individuals. J. clin. Invest. 36, 303–308 (1957).
Marks, B. H., B. G. Garber, and F. W. Mc coy: The juxtaglomerular apparatus as an extra-adrenal site of ACTH action. Proc. Soc. exp. Biol. (N.Y.) 105, 593–595 (1960).
Marks, L. J., R. Chute, J. V. I. O’Sullivan, and T. J. Giovanniello: Observations on the role of the adrenal in the electrolyte response to surgery. Metabolism 10, 610–620 (1961).
Martz, B. L., H. A. Kneubuhler, and O. M. Helmer: Constrictor activity of peripheral blood after renal artery clamping in dogs. Circulation 26, 757 (1962).
Marx, A. J., and H. W. Deane: Histophysiologic changes in the kidney and adrenal cortex in rats on a low sodium diet. Endocrinology 73, 317–328 (1963).
— — T. F. Mowles, and H. Sheppard: Chronic administration of angiotensin in rats; changes in blood pressure, renal and adrenal histophysiology and aldosterone production. Endocrinology 73, 329–337 (1963).
Masson, G. M. C., C. Kashii, and J. C. Panisset: Experimental vascular disease elicited by aldosterone and renin. Endocrinology 71, 505–512 (1962a).
— — — Transfer of experimental hypertension and vascular disease. Circulation 28, 764 (1963).
— — —, and I. H. Page: Relationship of renin content and secretion following treatment with corticosteroids. Circulation 26, 758 (1962b).
— A. Mikasa, and H. Yasuda: Transfer of experimental renal hypertension and vascular disease. Canad. med. Ass. J. 90, 231–235 (1964).
McCaa, C. S., T. Q. Richardson, R. B. Mccaa, L. L. Sulya, and A. C. Guyton: Decreased aldosterone secretion in Goldblatt hypertension. Circulation 28, 765 (1963).
McCall, M. F., and B. Singer: Studies in nephrosis: chemical corticoids, salt-retaining factor and effect of ACTH. J. clin. Endocr. 13, 1157–1168 (1953).
Mccubbin, J. W., and I. H. Page: Renal pressor system and neurogenic control of arterial pressure. Circulat. Res. 12, 553–559 (1963a).
— — Neurogenic component of chronic renal hypertension. Science 139, 210–215 (1963b).
McDonald, I. R., J. R. Goding, and R. D. Wright: Transplantation of the adrenal gland of the sheep to provide access to its blood supply. Aust. J. exp. Biol. med. Sci. 36, 83–96 (1958).
McDonald, R., and M. Reich: Corticosteroid secretion by the autotransplanted adrenal gland of the conscious sheep. J. Physiol. (Lond.) 147, 33–50 (1959).
McGiff, J. C.: Allocation of cardiac output to limb and kidney during hypotensive procedures. Amer. J. Physiol. 205, 541–548 (1963).
—, and H. D. Itskovltz: Reversal of angiotensin vasoconstrictor activity. Circulation 28, 767–768 (1963a).
— — Reversal of angiotensin vasoconstrictor activity during renal ischemia. Clin. Res. 11, 410 (1963b).
McGonigle, D. J., R. S. Seipel, and E. J. Wylie: Renal effect of temporary extensive infrarenal arterial occlusion: an experimental study. Surgery 49, 235–241 (1961).
McQueen, E. G.: The effect of control of blood pressure on vascular reactivity in experimental renal hypertension. Clin. Sci. 21, 133–140 (1961).
—, and R. B. I. Morrison: The effects of synthetic angiotensin and noradrenalin on blood pressure and renal function. Brit. Heart J. 23, 1–6 (1961).
Meakin, J. W., J. Bethune, R. H. Despointes, and D. H. Nelson: The rate of disappearance of ACTH activity from the blood of humans. J. clin. Endocr. 19, 1491–1494 (1959).
Mendlowitz, M., N. E. Naffchi, E. B. Bobrow, R. L. Wolf, and S. E. Gitlow: Effect of aldosterone on digital vascular reactivity to l.norepinephrine, in normotensive, hypertensive and hypotensive patients. Circulation 26, 761 (1962).
Merrill, A. J., J. L. Morrison, and E. S. Brannon: Concentration of renin in renal venous blood in patients with chronic heart failure. Amer. J. Med. 1, 468–472 (1946).
Merrill, J. P.: Diagnosis and treatment of renal hypertension of humoral origin. Anesthesiology 24, 479––486 (1963).
Metaxas, P., and G. M. Bull: The relation between right auricular pulsation and the excretion of water and salt. Clin. Sci. 23, 571–574 (1962).
Meyer, C. J., D. S. Layne, J. F. Tait, and G. Pincus: The binding of aldosterone to plasma proteins in normal, pregnant and steroidtreated women. J. clin. Invest 40, 1663–1671 (1961).
Mialhe-Voloss, C.: Posthypophyse et activité corticotrope. Acta endocr. (Kbh.) 28, Suppi. 35 (1958).
—, et E. E. Baulieu: Étude qualitative des corticostéroides libérés par la surrénale du Rat in vitro sous l’influence des hormones corticotropes antihypophysaire et posthypophysaire. C. R. Acad. Sci. (Paris) 246, 639–642 (1958).
Mikasa, A., and G. M. C. Masson: Effects of renal pressor system during hemorrhagic hypotension. Proc. Soc. exp. Biol. (N. Y.) 106, 315–316 (1961).
Millar, F. K., J. N. Toal, R. H. Brooks, J. O. Davis, and J. White: Increased aldosterone secretion by tumor-bearing rats. Amer. J. Physiol. 205, 189–194 (1963).
Miller, R. A.: Cytological phenomena associated with experimental activity in the adrenal cortex of mice. Amer. J. Anat. 86, 405–437 (1950).
— Hypophyseal and extra-hypophyseal factors affecting glomerular, nucleolar, and nuclear hypertrophy, following enucleation of the adrenal in the rat. Amer. J. Anat. 103, 187–199 (1958).
Miller, T. R., II., W. W. Faloon, and C. W. Lloyd: Divergence in magnesium sodium and potassium excretion during stimulation of endogenous aldosterone production. J. clin. Endocr. 18, 1178–1185 (1958).
Mills, I. H.: Sodium retaining steroids in non-oedematous patients; production of oedema and heart failure. Lancet 1962 I, 1264–1267.
— A. Casper, and F. C. Bartter: On the role of the vagus in the control of aldosterone secretion. Science 128, 1140–1141 (1958).
— H. E. de Wardener, C. J. Harper, and W. F. Clapham: Studies on the afferent mechanism of the sodium chloride diuresis which follows intravenous saline in the dog. Clin. Sci. 21, 259–264 (1961).
Mills, J. N., S. Thomas, and K. S. Williamson: The extent of the adrenal influence upon renal electrolyte excretion in the healthy man on a normal diet, and its contribution to the renal changes on standing. J. Endocr. 23, 365–373 (1962).
Miyabo, S.: The urinary excretion of aldosterone in hypertensive patients (in Japanese). Folia endocr. jap. 36, 1654–1676 (1961).
Moore, F. D.: Common patterns of water and electrolyte change in injury, surgery and disease. New Engl. J. Med. 268, 277–285, 325–333, 377–384, 427–432 (1958).
Moran, W. H., Jr., A. Martinson, and B. Zimmerman: Estimation of aldosterone in small human peripheral venous samples. Surg. Forum 12, 21–22 (1961).
Morris, R. E., Jr., P. A. Ransom, and J. E. Howard: Studies on the relation of angiotensin to hypertension of renal origin. J. clin. Invest. 41, 1386–1387 (1962).
—, and P. R. Robinson: A method for determination of angiotensin II in human blood. Bull. Johns Hopk. Hosp. 114, 127–145 (1964).
— —, and G. A. Schule: The relation of angiotensin to renal hypertension. Canad. med. Ass. J. 90, 272–276 (1964).
MüLLER, A. F.: Wasserhaushalt bei Herzinsuffizienz. Schweiz. med. Wschr. 92, 836–842 (1962a).
— Regulation der aldosterone secretion. Verh. Dtsch. Ges. inn. Med. 281, 529–544 (1962b).
— E. L. Manning, and A. Riondel: Diurnal variation of aldosterone. In: A. F. MüLLER and C. M. O’Connor (eds.), An Int. Symposium on Aldosterone, p. 111–127. London: J. & A. Churchill 1958.
MüLLER, A. F., A. M. Riondel et E. L. Manning: Influence de l’ACTH sur la sécrétion de l’aldosMrone. Helv. med. Acta 23, 572–577 (1956a).
— — — Mechanisms régulateurs de l’aldostérone chez l’homme. Helv. med. Acta 23, 610–618 (1956b).
Muirhead, E. E., E. G. Daniels, E. Booth, W. A. Freyburger, and J. W. Hinman: Medullorenal vasodepressor effect and the antihypertensive function of the kidney. Fed. Proc. 23, 515 (1964).
—, and M. Kosinski: Renal medulla and renoprival hypertension. Relationship between corticorenal (renin) and medullorenal extracts. Circulat. Res. 11, 674–680 (1962).
Muldowney, F. P., and P. Banks: Kaliuretic effect of heparin. Lancet 1960 I, 548–549.
Mulrow, P. J.: The role of the rennin-angiotensin system in the hypertension associated with renal vascular disease. Canad. med. Ass. J. 90, 277–280 (1964).
—, and W. F. Ganong: The effect of hemorrhage upon aldosterone secretion in normal and hypophysectomized dogs. J. clin. Invest. 40, 579–585 (1961a).
— — Stimulation of aldosterone secretion by angiotensin II. Yale J. Biol. Med. 33, 386–395 (1961b).
— — Role of the kidney and the rennin-angiotensin system in the response of aldosterone secretion to hemorrhage. Circulation 25, 213–220 (1962).
— — The role of the rennin-angiotensin system in the regulation of aldosterone secretion in the dog and man. In: E. E. Baulieu and P. Robel (eds.), Aldosterone, p.265–278. Oxford: Blackwell 1964.
— — Effect of simultaneous infusions of ACTH and angiotensin II upon aldosterone secretion of hypophysectomized nephrectomized dogs. Proc. Soc. exp. Biol. (N. Y.) 118, 195–197 (1965).
— —, and A. BORYCZKA: Further evidence for a role of the rennin-angiotensin system in the regulation of aldosterone secretion. Proc. Soc. exp. Biol. (N. Y.) 112, 7–10 (1963a).
— —, G. Cera, and A. Kuljian: The nature of the aldosterone-stimulating factor in dog kidney. J. clin. Invest. 41, 505–518 (1962).
— N. A. Powell, and R. L. Kahler: Angiotensin concentration in plasma of sodium-depleted humans. J. clin. Invest. 42, 959 (1963b).
— G. L. Schmagranoff, A. H. Lieberman, C. I. Slade, and J. A. Luetscher, Jr.: Stimulation of rat adrenocortical secretion by a factor present in human urine. Endocrinology 64, 631–637 (1959).
Murakawa, S.: Effects of splanchnic nerve stimulation on aldosterone secretion (in Japanese). Folia endocr. jap. 38, 1085–1097 (1963).
Murphy, R. J. F.: The effect of “rice diet” on plasma volume and extracellular fluid space in hypertensive subjects. J. clin. Invest. 29, 912–917 (1950).
Myers, R. M., W. R. Bishop, and B. T. Scheer: Anterior pituitary control of active sodium transport across frog skin. Amer. J. Physiol. 200, 444–450 (1961).
Mylon, E., and L. R. Freedman: On the occurrence of renin in the blood of hypertensive patients. Amer. Heart J. 38, 509–516 (1949).
NáDASDI, M.: Pituitary and adrenal influence on the “endocrine kidney” syndrome. J. Endocr. 22, 1–6 (1961).
Nairn, R. C., C. S. Chadwick, and K. B. Fraser: Purification of renin by electrophoresis, absorption and immunologic methods. Brit. J. exp Path. 41, 214–221 (1960).
Neher, R., P. Desaulles, I. E. Vischer, P. Wieland u. A. Wettstein: Isolierung, Konstitution und Synthese eines neuen Steroides aus Nebennieren. Helv. chim. Acta 41, 1667–1692 (1958).
— C. Meystre u. A. Wettstein: Neue 16α-Hydroxysteroide aus menschlichen Urin und aus Schweine-Nebennieren. Helv. chim. Acta 42, 132–152 (1959).
—, and A. Wettstein: Physiochemical detection and measurement of aldosterone in body fluids and tissues. Acta endocr. (Kbh.) 18, 386–395 (1955).
Nelson, D. H., and J. T. August: Abnormal response of oedematous patients to aldosterone or deoxycortone. Lancet 1909 II, 883–885.
Newman, A. F., E. S. Redgate, and G. Farrell: The effect of diencephalons-mesencephalon lesions on aldosterone and hydrocortisone secretion. Endocrinology 63, 723–736 (1958).
Nichols, J.: Effects of electrolyte imbalance on the adrenal glands. Arch. Path. 45, 717–721 (1948).
— The adrenal cortex of patients dying in hyponatremia. Inter. Physiol. Congr. 20, 678 (1956).
Nickerson, M., and M. C. Sutter: Angiotensin in shock. Canad. med. Ass. J. 90, 325–327 (1964).
Norman, N.: The influence of the concentration of sodium and potassium in the cerebrospinal fluid on the secretion of steroids, including aldosterone, from the adrenal cortex. Acta endocr. (Kbh.) 37, 559–564 (1961).
Olson, R. E., and H. W. Deane: A physiological and cytochemical study of the kidney and the adrenal cortex during acute choline deficiency in weanling rats. J. Nutr. 39, 31–55 (1949).
Omae, T., G. M. C. Masson, and I. H. Page: Release of renin in hypertensive rats. Amer. J. Physiol. 199, 637–643 (1960).
Orti, E., and E. P. Ralli: Purification and mode of action of a sodium-retention stimulating factor. Amer. J. Physiol. 199, 43–48 (1960).
Ostrovsky, D., and A. G. Gornall: Effects of aldosterone and other adrenal hormones on the blood pressure responses to renin and angiotensin. Canad. med. Ass. J. 90, 180–184 (1964).
Page, I. H.: The changing outlook for the hypertensive patient. Ann. intern. Med. 57, 96–109 (1962).
—, and F. M. Bumpus: Angiotensin. Physiol. Rev. 41, 331–390 (1961).
— — Angiotensin – a renal hormone. Recent Progr. Hormone Res. 18, 167–186 (1962).
—, and F. Olmstead: Hemodynamic effects of angiotensin, norepinephrine and bradykinin continuously measured in unanesthetized dogs. Amer. J. Physiol. 201, 92–96 (1961).
Paladini, A. C., E. Braun-MenéNDEZ, I. S. Del Frane, and Z. M. Massani: The estimation of angiotensin in blood. J. Lab. clin. Med. 53, 264–271 (1959).
—, and O. A. Scornik: Angiotensin blood levels in dogs during blood pressure depression. Excerpta med. (Amst.), Int. Congr. Ser. 48, Abstract No 190 (1962).
— —, and Z. M. Massani: The role of angiotensin in experimental hypertension (in Spanish). Acta physiol. lat.-amer. 12, 188–194 (1962).
PalkóVLTS, M., and P. I. FöLDVáRI: Effect of the subcommissural organ and the pineal body on the adrenal cortex. Endocrinology 72, 28–32 (1963).
Panagiotis, N. M., and G. F. Hungerford: Response of the pineal and adrenal glands to sodium restriction. Endocrinology 69, 217–224 (1961).
Pasqualino, A., and G. H. Bourne: Histochemical change in kidneys and adrenal of rats made hypertensive by the Goldblatt method. Nature (Lond.) 182, 1426–1427 (1958).
— — Comparative histochemical effects of a loose, non-compressive clip on one renal artery and a tight hypertension-producing clip. Acta anat. (Basel) 46, 311–342 (1961).
Pearce, J. W.: The effect of vagotomy and denervation of the carotid sinus on diuresis following plasma volume expansion. Canad. J. Biochem. 37, 81–90 (1959).
Peart, W. S.: Renin and hypertensin. Ergebn. Physiol. 50, 409–432 (1959).
— Possible relation between salt metabolism and the angiotensin system. In: K. D. Beok and P. T. Cottier (eds.), Essential hypertension, p.112–120. Berlin-Göttingen-Heidelberg: Springer 1960.
— Estimation of renin in body fluids. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
— J. J. Brown, D. D. Davies, A. F. Lever, and J. I. S. Robertson: The influence of sodium loading and sodium depletion on plasma renin in man. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
— J. I., S. Robertson, and D. G. Grarame-Smith: Examination of the relation of renin release to hypertension produced in the rabbit by renal-artery constriction. Circulat. Res. 9, 1171–1184 (1961).
Pechet, M.: Studies of secretion of aldosterone. Proc. 20th Int. Physiological Congr. 1956, p.714.
— R. H. Hesse, and H. Kohler: The metabolism of d-aldosterone: isolation and chemical identity of metabolites; distribution of free aldosterone and metabolism in tissues and fluids under physiological conditions. J. clin. Invest. 41, 1391 (1962).
Perloff, D., M. Sokolow, E. J. Wylie, D. R. Smith, and A. J. Palabinskas: Hypertension secondary to renal arterial occlusive disease. Circulation 24, 1286–1304 (1961).
Peters, G.: Renal tubular effect of val-5-angiotensin II amide in rats. Proc. Soc. exp. Biol. (N.Y.) 112, 771–775 (1963).
Peterson, R. E.: Metabolism of adrenocorticosteroids in man. Ann. N.Y. Acad. Sci. 82, 846–853 (1959a).
— The miscible pool and turnover rate of adrenocortical steroids in man. Recent Progr. Hormone Res. 15, 231–261 (1959b).
Peterson, R. E. and B. Miller: Determination of peripheral plasma aldosterone. Endocr. Soc. Abstract, 46th Annual Meeting 1964, p. 63.
—, and J. Miller: Aldosterone-stimulating material in urine. Endocrinology 71, 174–175 (1962).
Petronio, L., and G. Casirola: Some aspects of the exchange of the electrolytes and phosphates of plasma in response to treatment with pituitary extract (in Italian). Arch. Sci. med. 103, 99–105 (1957).
Pickering, G. W.: Introduction. In: M. Schacter (eds.), Polypeptides that affect smooth muscle and blood vessels, p. 97–98. London: Pergamon 1960.
— Discussion. Canad. med. Ass. J. 90, 166 (1964).
Pitcock, J. A., P. M. Hartroft, and L. N. Newmark: Increased renal pressor activity (renin) in sodium deficient rats and correlation with juxtaglomerular cell granulation. Proc. Soc. exp. Biol. (N.Y.) 100, 868–869 (1958).
Poll, M., M. W. Switchik, J. W. Canter, R. L. Segal, and I. D. Baronofsky: The effect of thyroidectomy on experimental ascites. Surgery 49, 636–640 (1961).
Proceedings of conference on hypertension. Circulation 17, No 4, part 2 (1958).
Prunty, F. T. G., P. H. Forsham, and G. W. Thorn: Desoxycorticosterone like activity induced by ACTH in man. Clin. Sci. 7, 109–120 (1948).
Purjesz, I., and G. Urbán: To the problem of control of aldosterone secretion. Excerpta med. (Amst.), Int. Congr. Ser. 51, 222 (1962).
Raab, W., J. J. Humphreys, N. Makons, R. de Grandpre, and W. Gigee: Pressor effects of epinephrine, norepinephrine and desoxycorticoacetate (DCA) weakened by sodium withdrawal. Circulation 6, 373–377 (1952).
Race, G. J., W. M. Nickey, P. S. Wolf, and E. J. Jordan: Studies on functional zonation of the adrenal cortex. Arch. Path. 64, 312–323 (1957).
— and H. M. Wu: Adrenal cortex functional zonation in the whale (Physeter catadon). Endocrinology 68, 156–158 (1960).
Randall, R. E., Jr., and S. Papper: Mechanism of postoperative limitation on sodium excretion: the role of extracellular fluid volume and adrenal cortex activity. J. clin. Invest. 37, 1628–1641 (1958).
Rapaport, A.,and A. G. Gornall: Secondary hyperaldosteronism in constrictive pericarditis. Canad. med. Ass. J. 85, 83–85 (1961).
Rapp, J. P.: Electrolyte and juxtaglomerular changes in adrenal regeneration hypertension. Amer. J. Physiol. 206, 93–104 (1964).
Rausohkolb, E. W., and G. L. Farrell: Evidence for diencephalic regulation of aldosterone secretion. Endocrinology 59, 526–531 (1956).
— —, and S. Koletsky: Aldosterone secretion after hypophysectomy. Amer. J. Physiol. 184, 55–58 (1956).
Reale, E., and O. Bucher: Sur l’ultrastructure d’appareil juxtaglomérulaire du rein. Experientia (Basel) 9, 430–431 (1961).
Rector, F. C., Jr., G. van Giesen, F. Kill, and D. W. Seldin: Influence of expansion of extracellular volume on tubular reabsorption of sodium independent of changes in glomerular filtrate rate and aldosterone activity. J. clin. Invest. 43, 341–348 (1964).
Regoli, D., H. Brunner, G. Peters, and F. Gross: Changes in renin content in kidneys of renal hypertensive rats. Proc. Soc. exp. Biol. (N.Y.) 109, 142–145 (1962).
Relman, A. S., and W. B. Schwarz: The effect of desoxycorticosterone acetate on electrolyte balance in normal man and its relation to sodium chloride intake. Yale J. Biol. Med. 24, 540–558 (1952).
Rennels, E. G., and R. E. Dill: Effect of pinealectomy on the histology and lipid content of the rat adrenal gland. Tex. Rep. Biol. Med. 19, 843–850 (1961).
Renold, A. E., J. Crabbé, L. Hernando-Avendano, D. H. Nelson, E. J. Ross, K. Emerson Jr., and G. W. Thorn: Inhibition of aldosterone secretion by amphenone in man. New Engl. J. Med. 256, 16–21 (1957).
Rick, W., G. Winkler, E. Koch, and H. Bohn: Clinical observations in hypoaldosteronism. Acta endocr. (Kbh.), Suppl. 67, 103 (1962).
Robertson, J. I. S.: Renin in plasma of normal and hypertensive rabbits. J. Physiol. (Lond.) 166, 27P (1963).
Roels, H.: Deoxyribonucleic acid content of the nuclei of the adrenal cortex of the white rat. Nature (Lond.) 182, 873–874 (1958).
Romani, J. D., et A. Keller: Le rôle du rein et de l’angiotensine dans la stimulation de la fonction minérale de la surrénale. Aun. Endocr. (Paris) 23, 344–348 (1962).
— — et L. E. Piotti: Action d’un extrait épiphysaire sur la distribution des lipides et des phosphates alcalines du cortex surrénal. Ann. Endocr. (Paris) 21, 79–85 (1961).
Roos, R. de, and C. C. de Roos: Angiotensin II: Its effects on corticoid production by chicken adrenals in vitro. Science 141, 1284–1285 (1963).
Rosas, R., A. Gomez, D. Montague, M. Gross, and S. W. Hoobler: Hemodynamic effects of renal transplants in hypertensive and control rats. Proc. Soc. exp. Biol. (N.Y.) 115, 4–8 (1964).
Rosemberg, E., M. Demany, E. Budnitz, R. Underwood, and R. S. Leard: Effects of administration of large amounts of d-aldosterone in normal subjects and in a patient with Sheehan’s syndrome. J. clin. Endocr. 22, 465–480 (1962).
Rosenfeld, G., E. Roselmberg, F. Ungar, and R. I. Dorfman: Regulation of the secretion of aldosterone-like material. Endocrinology 58, 255–261 (1956).
Rosnagle, R. S., and G. L. Farrell: Alterations in electrolyte intake and adrenal cortical secretion. Amer. J. Physiol. 187, 7–10 (1956).
Ross, E. J.: Aldosterone in clinical and experimental medicine. Oxford: Blackwell 1959.
— and E. K. McClean: The excretion of an aldosterone-stimulating hormone in the urine of sodium-deprived adrenalectomized rats. Clin. Sci. 22, 401–408 (1962).
— W. van’t Hoff, J. Crabbé, and G. W. Thorn: Aldosterone excretion in hypopituitarism and after hypophysectomy in man. Amer. J. Med. 28, 229–238 (1960).
— and W. W. Winternitz: The effect of an aldosterone antagonist on the renal response to sodium restriction. Clin. Sci. 20, 143–148 (1961).
Rosse, W. F., R. J. Berry, and T. A. Waldmann: Some molecular characteristics of erythropoietin from different sources determined by inactivation by ionizing radiation. J. clin. Invest. 42, 124–129 (1963).
Salya, L. L., C. S. McCaa, V. H. Read, and D. Bomer: Uptake of tritiated aldosterone by rat tissues. Nature (Lond.) 200, 788–789 (1963).
Sambhi, M. P., J. C. Beck, and E. H. Venning: Malignant hypertension and aldosterone secretion. Amer. J. Med. 35, 251–256 (1963).
Sanders, L. L., and J. C. Melby: Aldosterone excretion in congestive heart failure. Clin. Res. 11, 173 (1963).
Sapirstein, L. A., E. Ogden, and F. D. Southard, Jr.: Renin-like substance in blood after hemorrhage. Proc. Soc. exp. Biol. (N.Y.) 48, 505–508 (1941).
— F. D. Southard Jr., and E. Ogden: Restoration of blood pressure by renin activator after hemorrhage. Proc. Soc. exp. Biol. (N.Y.) 50, 320–324 (1942).
Sarason, F. L.: Morphologic changes in the rat’s adrenal cortex under various experimental conditions. Arch. Path. 35, 373–390 (1943).
Schaechtelin, G., D. Regoli, and F. Gross: Bio-assay of circulatory rennin-like pressor material by isovolemic cross circulation. Amer. J. Physiol. 205, 303–306 (1963).
Schaffenburg, C. A., E. Haas, and H. Goldblatt: Concentration of renin in kidneys and angiotensinogen in serum of various species. Amer. J. Physiol. 199, 788–792 (1960).
— G. M. C. Masson, and A. C. Corcoran: Renin inhibition of compensatory renal hypertrophy. Proc. Soc. exp. Biol. (N.Y.) 87, 469––473 (1954).
Scheele, G. A., P. A. Ransom, and R. E. Morris, Jr.: Studies on the site of action and destruction of angiotensin II. Clin. Res. 10, 391 (1962).
Scheer, B. T., K. Matsumoto, and G. Shane: Histological changes in the diencephalon of frogs in relation to osmo-regulatory control. Amer. Zoologist 2, 444 (1962).
Scheifley, C. H.: A new clinical syndrome producing hypertension-arterio-venous fistula of the kidney. J. Amer. med. Ass. 174, 1625–1627 (1960).
Scherrer, H.: Hypothalamic influences on electrical activity in the renal nerve of the rat. Acta neuroveg. (Wien) 23, 499–522 (1962).
Schlatmann, R. J. A. F. M., A. P. Jansen, H. Prenen, J. K. Vanderkarst, and C. L. H. Majoor: The natriuretic and aldosterone suppressive action of heparin and some related polysulfated polysaccharides. J. clin. Endocr. 24, 35–47 (1964).
— H. Prenen, A. P. Jansen, and C. L. H. Majoor: The natriuretic action of heparin and some related substances. Lancet 1960 I, 314–317.
Schlegel, J. V.: Renal hypertension. J. Amer. med. Ass. 183, 92–96 (1960).
Schmid, H. E., Jr.: Renin, a physiologic regulator of renal hemodynamics. Circulat. Res. 11, 185–190 (1962).
— Effect of antirenin formation on renal hemodynamics and electrolyte excretion in dogs. Fed. Proc. 22, 630 (1963).
—, and L. A. Graham: Juxtaglomerular cell changes in dogs with antirenin titers. Circulat. Res. 11, 853–856 (1962).
— — B. B. Brennan, and G. E. Wakerlin: Renin concentration of normotensive and hypertensive dog kidney. Circulat. Res. 10, 696–703 (1962).
Schwartz, J., R. Bloch, and J. Velly: Relation between renin, aldosterone and experimental hypertension in rats. Canad. med. Ass. J. 90, 243–244 (1964).
Schwartz, W. B., W. Bennett, S. Curelop, and F. C. Bartter: Syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Amer. J. Med. 23, 529–542 (1957).
Schwyzer, R., and H. Turrian: The chemistry and pharmacology of angiotensin. Vitam. and Horm. 18, 237–288 (1960).
Scian, L. F., C. D. Westermann, O. R. Kruesi, and J. G. Hilton: Effect of ACTH and vasopressin on aldosterone secretion. Fed. Proc. 18, 545 (1959).
Scornik, O. A., and A. C. Paladini: Angiotensin blood levels in dogs with experimental renal hypertension. Amer. J. Physiol. 201, 526–530 (1961).
Scornik, O. A., and A. C. Paladini: Significance of blood angiotensin levels in different experimental conditions. Canad. med. Ass. J. 90, 269–271 (1964).
— — and E. Braun-MenéNDEZ: Further improvements in a method for the estimation of angiotensin in blood. Acta physiol. lat.-amer. 10, 64–67 (1960).
Selkurt, E. E.: Effect of pulse pressure and mean arterial pressure modification on renal hemodynamics and electrolyte and water excretion. Circulation 4, 541–546 (1951).
— Sodium excretion by the mammalian kidney. Physiol. Rev. 34, 287–333 (1954).
Seller, R., M. Fuchs, C. Swartz, and O. Ramirez: Spirolactone effect on postoperative electrolytes and adrenal activity. Clin. Res. 10, 403 (1962).
Selye, H.: Adrenal changes produced by parenteral administration of highly hypertonic solutions. Acta neuroveg. (Wien) 6, 212–219 (1953).
— E. M. Rowley, and C. E. Hall: Changes in the adrenals following prolonged treatment with methyl-testosterone. Froc. Soc. exp. Biol. (N.Y.) 54, 140–143 (1943).
Sevy, R. W., and E. A. Ohler: Effect of renin on adrenal ascorbic acid concentration in rats. Amer. J. Physiol. 174, 471–474 (1953).
— and G. E. Wakerlin: Endocrine factors in experimental renal hypertension. Amer. J. Physiol. 172, 129–140 (1953).
Sheppard, H., R. Swenson, and T. F. Mowles: Steroid biosynthesis by rat adrenal: functional zonation. Endocrinology 73, 819–824 (1963).
Shoemaker, W. C., and A. G. Finder: Relation of potassium and glucose release from the liver in the unanesthetized dog. Proc. Soc. exp. Biol. (N.Y.) 108, 248–252 (1961).
Siegenthaler, W. E., A. Dowdy, and J. A. Luetscher, Jr.: Determination of the secretion rate of aldosterone in normal man by use of 7-H3-d-aldosterone and acid hydrolysis of urine. J. clin. Endocr. 22, 172–177 (1962).
Simkin, B., H. C. Bergman, H. Silver, and A. M. Prinzmetal: Renal arteriovenous anastamoses in rabbits, dogs and human Subjects. Arch. intern. Med. 81, 115–125 (1948).
Simonson, E., and J. BrožEK: Russian research on arterial hypertension. Ann. intern. Med. 50, 129–193 (1959).
Simpson, S. A., J. F. Tait, A. Wettstein, R. Neher, J. von Euw, O. Schindler. u. T. Reichstein: Aldosteron-Isolierung und Eigenschaften über Bestandteile der Nebennierenrinde und verwandte Stoffe. Helv. chim. Acta 37, 1163–1200 (1954).
Singer, B.: Effect of aldosterone-antagonist, SC 8109, on the secretion of aldosterone in normal rats. Endocrinology 65, 512–514 (1959).
— Further studies on the secretion of aldosterone by the rat adrenal gland. J. Endocr. 19, 310–324 (1960).
— C. Losito, and S. Salmon: Aldosterone and corticosterone secretion rates in rats with experimental renal hypertension. Acta endocr. (Kbh.) 44, 505–518 (1963).
— — — Studies on the effect of angiotensin II on adrenal cortical secretion in hypophysectomized rats. Endocrinology 74, 325–332 (1964).
—, and M. P. Stack-Dunne: The secretion of aldosterone and corticosterone by the rat adrenal. Nature (Lond.) 174, 790–791 (1954).
— — The secretion of aldosterone and corticosterone by the rat adrenal. J. Endocr. 12, 130–145 (1955).
—, and E. H. Venning: Method of assay of sodium-retaining factor in human urine. Endocrinology 52, 623–633 (1953).
—, and J. Wener: Excretion of sodium-retaining substances in patients with congestive heart failure. Amer. Heart J. 45, 795–801 (1953).
Sirotina, M. F.: Renin content of kidneys in experimental hypertension. Fed. Proc. 22, T1126–T1128 (1963).
Skeggs, L. T., Jr.: Polypeptides of the renal pressor system. In: M. Schachter (ed.), Polypeptides that affect smooth muscle and blood vessels, p.106–121. London: Pergamon 1960.
— J. R. Kahn, K. E. Lentz, and N. P. Shumway: Preparation, purification and amino-acid sequence of a polypeptide renin substrate. J. exp. Med. 106, 439–453 (1957).
— —, and N. P. Shumway: The isolation and assay of hypertensin from blood. J. exp. Med. 95, 241–246 (1952).
— K. E. Lentz, H. Hochstrasser, and J. R. Kahn: The chemistry of renin substrate. Canad. med. Ass. J. 90, 185–189 (1964).
— — J. R. Kahn, N. P. Shumway, and K. R. Woods: The amino-acid sequence of hypertensin II. J. exp. Med. 104, 193–197 (1956).
Skelton, F. R.: Adrenal regeneration and adrenal regeneration hypertension. Physiol. Rev. 39, 162–182 (1959).
Skinner, S. L., J. W. McCubbin, and I. H. Page: Angiotensin in blood and lymph following reduction in renal arterial perfusion pressure in dogs. Circulat. Res. 13, 336–345 (1963a).
— — — Renal baroceptor control of renin secretion. Science 141, 814–816 (1963b).
Slater, J. D. H., B. H. Barbour, H. H. Henderson, A. G. T. Casper, and F. C. Bartter: Influence of the pituitary and the rennin-angiotensin system on the secretion of aldosterone, cortisol and corticosterone. J. clin. Invest. 42, 1504–1520 (1963).
— H. H. Henderson, A. G. T. Casper, B. H. Barbour, and F. C. Bartter: Control of adrenal cortical activity by the rennin-angiotensin system with changes in renal blood flow. Clin. Res. 10, 256 (1962).
Slaton, P.E. Jr., and E. G. Biglieri: Hypertension and hyperaldosteronism of renal origin. Circulation 28, 826 (1963).
Smeby, R. R., F. M. Bumpus, P. A. Khairallah, I. H. Page, and P. J. Cheriathundam: Determination of angiotensin in blood. Circulation 28, 807 (1963).
Smith, H. W.: Salt and water volume receptors. Amer. J. Med. 23, 623–652 (1957).
Sokabe, H., and A. Grollman: Localization of blood pressure regulating and erythropoietic functions in rat kidney. Amer. J. Physiol. 203, 991–994 (1962).
— — Pressor activity of renal venous effluent of normal and hypertensive rats. Amer. J. Physiol. 205, 264–266 (1963).
— A. MIkasa, H. Yasude, and G. M. C. Masson: Adrenal cortex and renal pressor function. Circulat. Res. 12, 94–100 (1963).
Solyom, J., J. Sturcz, S. Kotra, and A. Salamon: Renin angiotensin and aldosterone secretion. Lancet 1963 I, 1376–1378.
Sonnenberg, H., and J. W. Pearce: Renal response to measured blood volume expansion in differently hydrated dogs. Amer. J. Physiol. 203, 344–352 (1962).
Spiller, P. J., and D. H. P. Streeten: Mechanism of the natriuretic action of D-amphetamine. Clin. Res. 11, 252 (1963).
Spink, W. W., J. A. Vick, J. C. Melby, and J. Finstad: Influence of aldosterone and angiotensin II on endotoxin shock in the primate. Proc. Soc. exp. Biol. (N.Y.) 112, 795–799 (1963).
Stachenko, J., and C. J. P. Giroud: Functional zonation of the adrenal cortex; pathways of corticosteroid biogenesis. Endocrinology 64, 730–742 (1959a).
— — Functional zonation of the adrenal cortex; site of ACTH action. Endocrinology 64, 743–752 (1959b).
Stamler, J., L. Dreifus, L. N. Katz, and I. J. Lichton: Response to rapid water, sodium and dextran loads of intact Ringer’s-infused unanesthetized dogs. Amer. J. Physiol. 195, 362–368 (1958a).
— — I. J. Lichton, E. Marcus, E. E. Hasbrouck, and S. Wong: Effects of ascites formation on response to rapid water, sodium and dextran loads in intact and diabetes insipidus Ringer’s-infused dogs. Amer. J. Physiol. 195, 369–372 (1958b).
Stark, G., u. H. Kossmann: Die Ausscheidung von Aldosteron, Natrium und Kalium nach fortlaufender hoher Progesterongabe. Acta endocr. (Kbh.). 42, 537–551 (1963).
—, u. U. Pfeifer: Die Wirkung hoher Oestrogen-Gaben auf die Ausscheidung von Aldosteron, Cortisol sowie Natrium und Kalium. Acta endocr. (Kbh.) 44, 216–224 (1963).
Stein, J. D., L. L. Bennett, A. A. Batts, and C. H. Li: Sodium, potassium, and chloride retention produced by growth hormone in the absence of the adrenals. Amer. J. Physiol. 171, 587–591 (1952).
Stein, R. M., B. H. Levitt, M. H. Goldstein, J. G. Porush, G. M. Eisner, and M. F. Levitt: The effects of salt restriction on the renal concentration operation in normal, hydropenic man. J. clin. Invest. 41, 2101–2111 (1962).
Stoerk, H. C., A. I. Knowlton, and E. N. Loeb: Correlation between serum potassium and the weight of the adrenal glomerulosa in rats. J. clin. Invest. 34, 965 (1955).
Strauss, M. B., R. K. Davis, J. D. Rosenbaum, and E. C. Rossmeisl: Production of increased renal sodium excretion by the hypotonic expansion of extra-adrenal fluid volume in recumbent subjects. J. clin. Invest. 31, 80–88 (1951).
Strauss, M. D., and L. E. Early: An inquiry into the role of “sodium-retaining” steroids in the homeostasis of body sodium in man. Trans. Ass. Amer. Phycns. 72, 200 (1959).
— E. Lamdin, W. P. Smith, and D. J. Bliefer: Surfeit and deficit of sodium. Arch. intern. Med. 102, 527–536 (1958).
Streeten, D. H. P., J. W. Conn, L. H. Lewis, S. S. Fajans, H. S. Seltzer, R. D. Johnson, R. D. Gittler, and A. H. Dube: The metabolic and adrenocortical responses of normal men to high environmental temperatures. J. Lab. clin. Med. 46, 957–958 (1955).
Strom, E. A., and J. D. Coffman: Aspirin and peripheral circulatory response to catacholamines and angiotensin. Clin. Res. 11, 174 (1963).
Suki, W., and A. Grollman: Role of the kidney in erythropoiesis. Amer. J. Physiol. 199, 629–632 (1960).
Swann, H. G.: The pituitary-adrenocortical relationship. Physiol. Rev. 20, 493–521 (1940).
— J. M. Prine, U. Moore, and R. D. Rice: The intrarenal pressure during experimental renal hypertension. J. exp. Med. 96, 282–291 (1952).
Sweeney, R.D., G.N. French, and W.O. O’Sullivan: The role of the liver in renal hypertension. Physiologist 5, 219 (1962).
Swingle, W.W., and A.J. Swingle: Effect of sodium pentobarbital anesthesia on plasma volume of adrenalectomized dogs. Amer. J. Physiol. 205, 555–559 (1963).
Tait, J.F.: The use of isotopic steroids for the measurement of production rates in vivo. J. clin. Endocr. 23, 1285–1297 (1963).
— B. Little, S.A.S. Tait, and C. Flood: The metabolic clearance rate of aldosterone in pregnant and nonpregnant subjects, estimated by both single injections and constant infusion methods. J. clin. Invest. 41, 2093–2100 (1962).
— S.A.S. Tait, B. Little, and R.R. Laumas: The disappearance of 7H3-d-aldosterone in the plasma of normal subjects. J. clin. Invest. 40, 72–80 (1961).
Takeuchi, J., S. Yagi, S. Nakayama, T. Ikeda, E. Uchida, G. Inoui, F. Shintani, and H. Ueda: Experimental studies on the nervous control of the renal circulation-effect of the electrical stimulation of the diencephalon on the renal circulation. Jap. Heart J. 1, 288–299 (1960).
Talanti, S., and A. Eisalo: The hypothalamo-hypophysial neurosecretory system in experimental hypertension in the rat. J. Endocr. 26, 107–111 (1963).
Tanner, W.D., and G.E. Hungerford: Sodium and potassium excretion in pinealectomized and adrenalectomized rats. Proc. Soc. exp. Biol. (N.Y.) 109, 388–390 (1962).
Taquini, A.C.: Neurogenic control of peripheral resistance in renal hypertension. Circulat. Res. 12, 562–567 (1963).
— P. Blaquier, and A.C. Taquini, Jr.: On the production and role of renin. Canad. med. Ass. J. 90, 210–213 (1964).
Taquini, A.C., Jr., P.C. Blaquier, and D.F. Bohr: Neurogenic factors and angiotension in etiology of hypertension. Amer. J. Physiol. 201, 1173–1175 (1961).
—, and A.C. Taquini: The rennin-angiotensin system in hypertension. Amer. Heart. J. 62, 558–564 (1961).
— — Angiotensin tachyphylaxis in the rat. Acta physiol. lat.-amer. 13, 159–164 (1963).
Taylor, A.N., and G. Farrell: Effect of brain stem lesions on aldosterone and cortisol secretion. Endocrinology 70, 556–566 (1962).
— — Facteur glomérulotrope. Ann. Endocr. (Paris) 24, 228–232 (1963).
— W.M. Mcisaac, and G. Farrell: Steroidogenic properties of l-methyl-6-methoxy-tetrahydro carboline. Fed. Proc. 21, 186 (1962).
Taylor, R.E., Jr., and M.J. Fregly: Renal response of propylthiouracil-treated rats to injected mineralocorticoids. Fed. Proc. 22, 210 (1963).
Thal, A.P., T.B. Grage, and R.L. Vernier: Function of the contralateral kidney in renal hypertension due to renal artery stenosis. Circulation 27, 36–43 (1963).
Thorn, G.W., J. Crabbé, L. Hernando-Avendano, F. J. Ross, D. H. Nelson, J. Hoet et A. E. Renold: Etudes sur la signification de la sécrétion de l’aldostérone chez l’homme. Bruxe.-méd. 37, 415–428, 459–469 (1957b).
— E.J. Ross, J. Crabbé, and W. van’t Hoff: Studies on aldosterone secretion in man. Brit. med. J. 1957a II, 955–966.
Tobian, L.: Physiology of the juxtaglomerular cells. Ann. intern. Med. 52, 395–410 (1960a).
— Interrelation of electrolytes, juxtaglomerular cells and hypertension. Physiol. Rev. 40, 280–312 (1960b).
— Relation of juxtaglomerular apparatus to renin and angiotensin. Circulation 25, 189–192 (1962).
— Sodium, renal artery distension and the juxtaglomerular apparatus. Canad. med. Ass. J. 90, 160–162 (1964).
—, and K. Coffee: Effect of thiazide drugs on renovascular hypertension in contrast to their effect on essential hypertension. Proc. Soc. exp. Biol. (N. Y.) 115, 196–198 (1964).
— — D. Ferreira, and J. Meuli: The effect of renal perfusion pressure on the net transport of sodium out of distal tubular urine as studied with the stop-flow technique. J. clin. Invest. 43, 118–128 (1964).
— J. Janecek, J. Coker, and D. Ferreira: Effect of chlorothiazide on renal juxtaglomerular cells and tissue electrolytes. Amer. J. Physiol. 202, 905–908 (1962a).
— —, and A. Tomboulian: Correlation between granulation of juxtaglomerular cells and extractable renin in rats with experimental hypertension. Proc. Soc. exp. Biol. (N. Y.) 100, 94–96 (1959).
— S. Perry, and J. Mark: The relation of the juxtaglomerular apparatus to sodium retention in experimental nephrosis. Ann. intern. Med. 57, 382–388 (1962b).
— J. Thompson, R. Tuedt, and J.J. Janecek: The granulation of juxtaglomerular cells in renal hypertension, adrenal regeneration hypertension and adrenal insufficiency. J. clin. Invest. 37, 660–671 (1958).
TUrgeon, C., and S. C. SOmmers: Juxtaglomerular cell counts and human hypertension. Amer. J. Path. 38, 227–241 (1961).
Ulick, S., J. H. Laragh, and S. Lieberman: The isolation of a urinary metabolite of aldosterone and its use to measure the rate of secretion of aldosterone by the adrenal cortex of man. Trans. Ass. Amer. Physcns 71, 225–235 (1958).
—, and K. K. Vetter: The secretion of aldosterone and 18-hydroxycorticosterone in man. In: E. E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
Upton, P. D., F. W. Dunihue, and W. F. Chambers: Subcommissural organ and water metabolism. Amer. J. Physiol. 201, 711–713 (1961).
Urquhart, J., and J. O. Davis: Role of the kidney and the adrenal cortex in congestive heart failure. Mod. Conc. cardiov. Dis. 32, 781–787 (1963).
—., —, and J. T. Higgins, Jr.: Effects of prolonged infusion of angiotensin II in normal dogs. Amer. J. Physiol. 205, 1241–1246 (1963a).
—., —, and —. Independence of glomerular filtration rate and the abnormal sustained renal response to the sodium retaining action of electrolyte-active steroids. Physiologist 6, 290 (1963b).
Usami, S., B. Peric, and S. Chien: Release of antidiuretic hormone due to common carotid occlusion and its relation with vagus nerve. Proc. Soc. exp. Biol. (N. Y.) 111, 189–193 (1962).
Vaamonde, C. A., I. N. Sporn, R. G. Lancestremere, J. L. Belsky, and S. Papper: Augmented natriuretic response to acute sodium infusion after blood pressure elevation with metaraminol in normotensive subjects. J. clin. Invest. 34,496–502 (1964).
Vander, A. J.: Inhibition of distal tubular sodium reabsorption with angiotensin II. Amer. J. Physiol. 205, 133–138 (1963).
Venning, E. H., and O. J. Lucis: Effect of growth hormone on the biosynthesis of aldosterone in the rat. Endocrinology 70, 486–491 (1962).
—., —, and —: Effect of corticotrophin and prednisone on the excretion of aldosterone in man. J. clin. Endocr. 16, 1541–1553 (1956a).
—, —, and —: The effect of anxiety upon aldosterone excretion in man. J. clin. Endocr. 17, 1005–1008 (1957 a).
—., —, J. B. Dosseter, and J. C. Beck: Influence of alterations in sodium intake on urinary aldosterone response to corticotropin in normal individuals and patients with essential hypertension. Metabolism 11, 254–264 (1962).
—., — C. J. P. Giroud, and J. C. Beck: Effect of growth hormone on aldosterone excretion. Metabolism 5, 697–702 (1956b).
—, —, —, and —: Factors affecting aldosterone excretion. Canad. med. Ass. J. 77, 773–777 (1957b).
—., —, L. Lowenstein, and J. Beck: Metabolic studies in pregnancy and the puerperium. J. clin. Endocr. 19, 403–424 (1959).
—., J. R. McCorriston, I. Dyrenfurth, and J. Beck: Aldosterone excretion following trauma. Metabolism 7, 293–300 (1958).
Verdesca, A. S., C. D. Westermann, R. S. Crampton, W. C. Black, R. I. Nedeljkovic, and J. G. Hilton: Direct adrenocortical stimulatory effect of serotonin. Amer. J. Physiol. 201, 1065–1067 (1961).
Verniory, A., and P. Potvliege: Effects of cortexone and salt on renin content, juxtaglomerular index and renal hypertension in rabbits. Proc. Soc. exp. Biol. (N. Y.) 115, 18–21 (1964).
Vertes, V., J. A. Granel, and H. Goldblatt: Renal arteriography, separate renal function studies and renal biopsy in human hypertension. New Engl. J. Med. 270, 656–659 (1964).
Veyrat, R., J. de Champlain, R. Boucher, and O. Genest: Measurement of human arterial renin activity in some physiological and pathological states. Canad. med. Ass. J. 90, 215–220 (1964).
Viar, W., and T. Lombardo: Effects of posture and of compression of the neck on glomerular filtration. Amer. J. Med. 9, 407 (1950).
Vito, E. de, I. Gómez, and J.C. Fasciolo: The angiotensin content of the renal blood in normal dogs. Acta physiol. lat.-amer. 13, 49–53 (1963).
Vogel, J. H. K.: Aldosterone in cerebral salt wasting. Circulation 27, 44–50 (1963).
Voth, D., M. Kohlhardt. u. K. W. Tietze: Zur Frage der renalen Steuerung der Zona glomerulosa der NNR. Klin. Wschr. 41, 443–439 (1963).
Wagner, H.N., Jr.: The influence of autonomic vasoregulatory reflexes on the rate of sodium and water excretion in man. J. clin. Invest. 36, 1319–1327 (1957).
—., Orthostatic hypotension. Bull. Johns Hopk. Hosp. 105, 322–359 (1959).
Wakerlin, G. E.: Endocrine factors in renal hypertension. Physiol. Rev. 35, 555–582 (1955).
—.: Antibody to renin as proof of the pathogenesis of sustained renal hypertension. Circulation 17, 653–657 (1958).
Wakerlin, G. E., and G. R. Chobot: Does renin play a role in the maintenance of of normal blood pressure? Proc. Soc. exp. Biol. (N. Y.) 40, 331–334 (1939).
Wal, B. van der, J. Moll, and D. de Wied: The effect of pinealectomy and of lesions in the subcommissural body on the rate of aldosterone secretion by rat adrenals in vitro. Abstracts of Papers, Int. Round-Table Conf. on the Epiphysis Cerebri. Amsterdam July 10–13, 1963.
—, and D. de Wied: Aldosterone secretion in vitro. Acta physiol. pharmacol. neer. 12, 181–182 (1963).
Walthard, B.: Funktionen der Nebennierenrinde, insbesondere der Zona glomerulosa. Acta endocr. (Kbh.) 5, 61–85 (1950).
Wardener, H. E. de, I. H. Mills, W. F. Clapham, and C. J. Hayter: Studies on the efferent mechanism of the sodium diuresis which follows the administration of intravenous saline in the dog. Clin. Sci. 21, 249–258 (1961).
Wardlaw, J. M., and R. L. Pike: Some effects of high and low sodium intake during pregnancy in the rat. IV. Granulation of renal juxtaglomerular cells and zona glomerulosa width. J. Nutr. 80, 355–364 (1963).
Warzynski, R., Y. Demirjian, and S. Hoobler: A method for the determination of “renin” in blood and some preliminary findings. Canad. med. Ass. J. 90, 225–226 (1964).
Watanabe, M., O. V. Dominguez, C. I. Meeker, E. A. H. Sims, M. J. Gray, and S. Solomon: Aldosterone and progesterone secretion in pregnancy. J. clin. Invest. 41, 1408–1409 (1962).
—., C. I. Meeker, M. J. Gray, E. A. H. Sims, and S. Solomon: Secretion rate of aldosterone in normal pregnancy. J. clin. Invest. 42, 1619–1631 (1963).
Wathen, R. L., W. S. Kingsbury, D. A. Strouder, and H. H. Rosterfer: Renin release during catacholamine infusion into the renal artery of the dog. Fed. Proc. 23, 437 (1964).
Weber, A. F., W. R. Pritchard, and A. F. Sellers: The production of lipid accumulation and other histological and cytological changes in the zona glomerulosa of calves. Amer. J. vet. Res. 17, 402–409 (1956).
Weisz, P., and V. Kemény: Aldosterone production of compensated hypertrophic adrenals. Experientia (Basel) 19, 540–541 (1963).
Welt, L.G. (ed.): Essays in metabolism. J. P. Peters Memorial Issue of Yale J. Biol. Med., vol. 29, 1956. Boston: Little, Brown & Co. 1957.
Wesson, L.G., Jr., and D.P. Lauler: Diurnal cycle of glomerular filtration rate and sodium chloride excretion during responses to altered salt and water balance in man. J. clin. Invest. 40, 1967–1977 (1961).
Wexler, B. C.: Lipid depletion of the zona glomerulosa of the rat adrenal cortex after administration of 9α-fluorohydrocortisone. Endocrinology 64, 300–304 (1959).
—.: Histological alterations in the adrenal cortex of intact and hyposectomized rats following ACTH, pitressin and adrenal steroids. Endocrinology 72, 149–158 (1963).
—, and A. P. Rinfret: Histological observations on the zona glomerulosa of the rat adrenal cortex following administration of corticotrophin preparations. Endocrinology 57, 608–620 (1955).
—, —, A. C. Griffin, and H. L. Richardson: Evidence for pituitary control of the lipid content of the zona glomerulosa of the rat adrenal cortex. Endocrinology 56, 120–123 (1955).
Wiedman, M. L., F. W. Dunihue, and W. van B. Robertson: Effect of sodium chloride intake and mineralocorticoid level on the granularity of the juxtaglomerular cells. J. Endocr. 17, 261–264 (1958).
Williams, H. E., P. L. Johnson, and J. B. Field: In vitro studies on the effect of ACTH in rat and bovine adrenal glands. Endocrinology 71, 293–297 (1962).
Williams, J. R., Jr., J. T. Diaz, J. C. Burch, and T. R. Harrison: The relation of the adrenal glands to the action of renal pressor substances. Amer. J. med. Sci. 198,212–219 (1939).
Wilson, I. D., and F. C. Goetz: Selective hypoaldosteronism after prolonged heparin administration. Amer. J. Med. 36, 635–640 (1964).
Winer, B. M.: Humoral vasoconstrictor effect of diuretics. Circulation 26, 805 (1962).
—., A vasoconstrictor effect of plasma during salt depletion. J. clin. Invest. 42, 994 (1963).
Winkler, G., W. Rick, B.v. Kügelgen u. E. Koch: Klinische Beobachtungen bei Hypoaldosteronismus. Verh. dtsch. Ges. inn. Med. 68, 671–677 (1962).
Wise, B.L., and W.F. Ganong: The effect of ablation of the area postrema on water and electrolyte metabolism in dogs. Acta neuroveg. (Wien) 22, 14–32 (1960a).
—., and —: Effect of brain stem stimulation on renal function. Amer. J. Physiol. 198, 1291–1295 (1960b).
Wislocki, G.B., and E.H. Leduc: The cytology and histochemistry of the subcommissural organ, and Reissner’s fiber in rodents. J. comp. Neurol. 97, 515–544 (1952).
Wolf, R.L., M. Mendolowitz, S. Gitlow, and N. Naftchi: In vitro degradation of angiotensin II131 in normotensive and hypertensive human subjects. Circulation 24, 1074 (1961).
—., —, —, and — The metabolism of angiotensin II. Circulat. Res. 11, 195–205 (1962).
—., —, —, J. Roboz, and N. Naftchi: Angiotensin II degradation by human Cohn plasma fractions. Proc. Soc. exp. Biol. (N.Y.) 112, 209–212 (1963).
—., — J. Roboz, N.E. Naftchi, and S.E. Gitlow: Recent studies on I131-labelled angiotensin II and analogues. Canad. med. Ass. J. 90, 295–298 (1964).
Wolff, H.P., K.R. Koczorek, and E. Buchborn: Aldosteronuria in oedema. In: A.F. Müller and C.M. O’Connor (eds.), An Int. Symposium on Aldosterone, p. 193–206. London: Churchill 1958.
—., — W. Jesch, and E. Buchborn: Untersuchungen über die Aldosteronausscheidung bei Leberkranken. Klin. Wschr. 34, 366–371 (1956).
—., and M. Torbica: Detection of plasma-aldosterone. Lancet 1963 I, 1346–1347.
Wright, R.D.: Control of secretion of aldosterone. Brit. med. Bull. 18, 159–163 (1962).
Wrong, O.M.: Hyperaldosteronism secondary to renal ischemia. In: E.E. Baulieu and P. Robel (eds.), Aldosterone. Oxford: Blackwell 1964.
Wurtman, R.J., M.D. Altschule, and U. Holmgran: Effects of pinealectomy and of a bovine pineal extract in rats. Amer. J. Physiol. 197, 108–110 (1959).
—., —, R.O. Greep, J.L. Falk, and G. Grave: The pineal gland and aldosterone. Amer. J. Physiol. 199, 1109–1111 (1960).
—, W. Roth, M.D. Altschule, and J.J. Wurtman: Interactions of the pineal and exposure to continuous light on organ weights of female rats. Acta endocr. (Kbh.) 36, 617–624 (1961).
Yamada, T.: The effect of electrical ablation of the nuclei habenulae, pineal body and sub-commissural organ on endocrine function, with special reference to thyroid function. Endocrinology 69, 706–711 (1961).
Yamauchi, H., and J. Hopper, Jr.: Pure nephrosis in an adult patient. Ann. intern. Med 55, 464–471 (1961).
Yankopoulos, N.A., J.O. Davis, B. Kliman, and R.E. Peterson: Evidence that a humoral agent stimulates the adrenal cortex to secrete aldosterone in experimental secondary hyperaldosteronism. J. clin. Invest. 38, 1278–1289 (1959).
Yates, F.E.: Effects of central venous congestion on sodium, potassium and water metabolism in the rat: response to desoxycorticosterone. Amer. J. Physiol. 194, 57–64 (1958).
—, J. Urquhart, and A.L. Herbst: Impairment of the enzymatic inactivation of adrenal cortical hormones following passive venous congestion of the liver. Amer. J. Physiol. 194, 65–71 (1958).
Yoshinaga, K., M. Aida, M. Maebashi, T. Sato, K. Abe, and I. Miwa: Assay of renin in peripheral blood. Tohoku J. exp. Med. 80, 32–41 (1963).
Zaugheri, E.O., H. Campana, F. Ponce, J.C. Silva, F.O. Fernandez, and J.R.E. Suarez: Production of erythropoietin by anoxic perfusion of the isolated kidney of a dog. Nature (Lond.) 199, 572–573 (1963).
Zimmerman, B.G.: Effect of acute sympathectomy on responses to angiotensin and nor-epinephrine. Circulat. Res. 11, 780–787 (1962).
Editor information
Rights and permissions
Copyright information
© 1968 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Ganong, W.F., Van Brunt, E.E. (1968). Control of Aldosterone Secretion. In: Deane, H.W., Rubin, B.L. (eds) The Adrenocortical Hormones. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 14 / 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-99938-3_2
Download citation
DOI: https://doi.org/10.1007/978-3-642-99938-3_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-99940-6
Online ISBN: 978-3-642-99938-3
eBook Packages: Springer Book Archive