Thoraxtumoren pp 359-365 | Cite as

Maligne Lymphome des Mediastinums

Spezielle diagnostische und therapeutische Probleme der großen Lymphadenopathie
  • C. Manegold
  • M. Eble
  • E. Anyanwu

Zusammenfassung

Maligne Lymphome können isoliert im Mediastinum entstehen oder als mediastinale Beteiligung eines generalisierten lymphomatösen Prozesses in Erscheinung treten. Das Spektrum mediastinaler Lymphome erstreckt sich vom zufällig diagnostizierten diskreten Befall einzelner Lymphknoten (kleiner Mediastinaltumor) bis hin zu großen Mediastinaltumoren, die das klinische Bild bestimmen und schließlich zur Diagnose führen können. Mediastinale Raumforderungen können asymptomatisch verlaufen oder von einer sehr vielfältigen Symptomatik begleitet sein. Sie entwickeln sich auf relativ engem Raum in unmittelbarer Umgebung lebenswichtiger Organe. Durch Kompression und Infiltration kann es zu Funktionsstörungen der Trachea, des Ösophagus, der Schilddrüse, der Nn. phrenici, der Lungen, des Herzens sowie der großen Gefäße kommen. Darüber hinaus wird das klinische Bild durch die Histologie und das Proliferationsverhalten des Tumors bestimmt. Maligne Lymphome des Mediastinums führen nicht selten zu Pleura- und Perikardergüssen [1,31]. Eine Korrelation zwischen der Größe der mediastinalen Raumforderung und der sogenannten B-Symptomatik ist nicht gegeben. Weniger als 50% aller diagnostizierten Mediastinaltumoren sind symptomatisch [34].

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1991

Authors and Affiliations

  • C. Manegold
  • M. Eble
  • E. Anyanwu

There are no affiliations available

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