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Ablagerungsdermatosen, Hautveränderungen bei Stoffwechselstörungen und Mangelsyndromen

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Therapie der Hautkrankheiten

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Zusammenfassung

Gicht ist auf eine heterogene Störung des Purinstoffwechsels zurückzuführen und manifestiert sich durch Hyperurikämie im Serum sowie durch Ablagerung von Uratkristallen im Gelenkbereich bzw unter der Haut. Vor allem Männer ab dem 40. Lebensjahr sind betroffen. Im Verlauf treten rezidivierend akute Gichtanfälle, vorzugsweise in den Gelenken der distalen Extremitäten (Podagra) auf. Bei chronischem Verlauf kommt es zu destruierenden Gelenkveränderungen, Nephrolithiasis und anderen Nephropathien. An der Haut kommt es vorzugsweise im Bereich der äußeren Helix der Ohren sowie an den Finger- und Zehengelenken zur Entstehung von Gichttophi infolge von Uratkristallablagerungen.

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Authors and Affiliations

  1. Universitäts-Hautklinik und Poliklinik, Klinikum Benjamin Franklin der Freien Universität Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland

    Prof. Dr. Prof. h.c. Constantin E. Orfanos & Prof. Dr. Claus Garbe

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  1. Prof. Dr. Prof. h.c. Constantin E. Orfanos
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  2. Prof. Dr. Claus Garbe
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© 1995 Springer-Verlag Berlin Heidelberg

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Orfanos, C.E., Garbe, C. (1995). Ablagerungsdermatosen, Hautveränderungen bei Stoffwechselstörungen und Mangelsyndromen. In: Therapie der Hautkrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97602-5_31

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  • DOI: https://doi.org/10.1007/978-3-642-97602-5_31

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