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Pharmaceutical Quality and Stability of Contrast Media

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Abstract

The production process for sterile solutions of CM, which are often injected or infused in large volumes, can be thought of in terms of the following steps:

  1. 1.

    Preparation of the solution

  2. 2.

    Filtration

  3. 3.

    Filling

  4. 4.

    Sterilization

  5. 5.

    Visual inspection.

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References

  1. Sovak M (ed) (1984) Radiocontrast agents. Springer, Berlin Heidelberg New York

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  2. Turco S, David NM (1973) Clinical significance of particulate matter. Hosp Pharm 8: 137–140

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  3. Kido DK, King PK, Manziona JV, Simon JH (1988) The role of catheters and guidewires in the production of angiographic thromboembolic complications. Invest Radiol 23: S359–S364

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© 1993 Springer-Verlag Berlin Heidelberg

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Wolden, B., Herrmann, D., Dawson, P., Thelen, M. (1993). Pharmaceutical Quality and Stability of Contrast Media. In: Dawson, P., Clauß, W. (eds) Contrast Media in Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97530-1_2

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  • DOI: https://doi.org/10.1007/978-3-642-97530-1_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57187-2

  • Online ISBN: 978-3-642-97530-1

  • eBook Packages: Springer Book Archive

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