Abstract
Bone marrow transplantation is a complex procedure. However, the basic purpose is that of transferring normal lymphohemopoietic stem cells for lymphohemopoietic reconstitution, and to supply cells with normal genetic information central to metabolic pathways in the recipient organism. At present these functions are incompletely achieved. Consequently, the future of marrow transplantation will depend upon increasing the efficacy of these functions and lessening associated side effects. Quite likely the next generation of marrow transplantation will be different, in appearance, from the procedures used at the present time. The most important problems still to be mastered are those of recurrence of the underlying disease, prevention of GVHD without jeopardizing engraftment, prevention of infection and prevention of delayed adverse effects.
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© 1992 Springer-Verlag Berlin Heidelberg
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Deeg, H.J., Klingemann, HG., Phillips, G.L. (1992). Outlook. In: A Guide to Bone Marrow Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97374-1_24
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DOI: https://doi.org/10.1007/978-3-642-97374-1_24
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