Vitamin A (Retinol)

  • Gerd Plewig
  • Albert M. Kligman


Vitamin A is readily available anywhere around the corner: drug stores, supermarkets, health shops, pharmacies and, of course, all without a prescription. Many laymen think retinol has multiple benefits in promoting health. Vitamin A (retinol) was formerly extolled as a remedy for acne. It is still praised by some, and still used widely as a supplementary agent to other therapies. At least half a dozen multiple-combination drugs are registered alone in Germany for the treatment of acne, containing between 10000 and 50000 IU of retinol palmitate per dose, often in combination with other vitamins and assorted nutrients. Studies have shown that the amount of oral vitamin A that produces significant therapeutic effect is of the order of 300000–400000 IU units a day.


Lichen Planus Oral Vitamin Oral Retinoid Significant Therapeutic Effect Recommended Daily Dose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Goodman DS (1979) Vitamin A and retinoids: recent advances. Introduction, background, and general overview. Fed Proc 38:2501–2503PubMedGoogle Scholar
  2. Kligman AM, Leyden JJ, Mills O Jr (1981) Oral vitamin A (retinol) in acne vulgaris. In: Orfanos CE, Braun-Falco O, Farber EM, Grupper C, Polano MK, Schuppli R (eds) Retinoids. Advances in basic research and therapy. Springer, Berlin Heidelberg New York, pp 245–253Google Scholar
  3. Muenter MD, Perry HO, Ludwig J (1971) Chronic vitamin A intoxication in adults. Am J Med 50:129–136PubMedCrossRefGoogle Scholar
  4. Rollman O, Vahlquist A (1985) Vitamin A in skin and serum — studies of acne vulgaris, atopic dermatitis, ichthyosis vulgaris and lichen planus. Br J Dermatol 113:405–413PubMedCrossRefGoogle Scholar
  5. Stüttgen G (1975) Oral vitamin A acid therapy. Acta Derm Venereol [Suppl] (Stockh) 74:174–179Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • Gerd Plewig
    • 1
  • Albert M. Kligman
    • 2
  1. 1.Dermatologische Klinik und PoliklinikUniversität MünchenMünchen 2Germany
  2. 2.School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA

Personalised recommendations