Today dermatologists rightly feel confident when it comes to the treatment of acne. Topical and systemic drugs are now available which are highly effective in controlling the disease, even curing it. These impressive therapeutic resources are recent. Older physicians still remember the times when actually very little was available. They mainly dispensed enthusiasm and hope, along with drugs which were only marginally useful and sometimes harmful. We will briefly review the history of therapy because it illustrates how difficult it is to establish the safety and efficacy of drugs. It also reminds us to maintain a healthy scepticism regarding some of our current approaches which may also turn out to be passing fads.
KeywordsResis Androgen Estradiol Tetracycline Aldosterone
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