During and following marrow transplantation the eye can be damaged in many ways. The conjunctivae can be affected by certain chemotherapeutic agents and by viruses, the lacrimal glands can be involved by chronic GVHD, and there can be retinal hemorrhage and choroiditis (see above). In addition, there can be longterm effects, mostly affecting the lens.


Leukemia Fractionation Cataract Busulfan Choroiditis 


  1. Deeg HJ, Flournoy N, Sullivan KM, Sheehan K, Buckner CD, Sanders JE, Storb R, With-erspoon RP, Thomas ED (1984) Cataracts after total body irradiation and marrow transplantation: A sparing effect of dose fractionation. Int J Radiation Oncology Biol Phys 10: 957CrossRefGoogle Scholar
  2. Franklin RM, Kenyon KR, Tutschka PJ, Saral R, Green WR, Santos GW (1983) Ocular manifestations of graft-vs-host disease. Ophthalmology 90: 4PubMedGoogle Scholar
  3. Jack MK, Jack GM, Sale GE, Shulman HM, Sullivan KM (1983) Ocular manifestations of graft versus host disease. Arch Ophthamol 101: 1080CrossRefGoogle Scholar
  4. Wara WM, Irvine AR, Neger RE, Howes EL, Phillips TL (1979) Radiation retinopathy. Int J Radiation Oncology Biol Phys 5: 81Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • H. J. Deeg

There are no affiliations available

Personalised recommendations