Buccal Nitroglycerin

  • Adam Schneeweiss
  • Marija Weiss


An interesting attempt to use nitroglycerin for long periods and avoid firstpass hepatic elimination was made by the development of buccal nitroglycerin tablets. Only a few clinical studies have been reported with this method, and it is seldom used in clinical practice. Nevertheless it deserves description because it emphasizes some of the problems of nitroglycerin therapy for long durations and sug¬gests solutions for them. Although transdermal administration of nitroglycerin is the method most widely used for long-term nitroglycerin therapy, buccal administration may be useful in some patients with cutaneous problems.



Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Adam Schneeweiss
    • 1
  • Marija Weiss
    • 2
  1. 1.Tel AvivIsrael
  2. 2.Köln 71Germany

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