Diagnosis of cirrhosis in mice is relatively easy on gross examination. The liver is shrunken and nodular and has a scarred, uneven capsule (Fig. 90). Some lobes may be more severely affected than others and large nodules (more than 1 cm in diameter) may be present.
SynonymsHepatic fibrosis nodular hyperplasia chronic toxic hepatitis cirrhosis, postnecrotic, toxic, biliary, or pericellular
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- Edwards JE, Dalton AJ (1942) Induction of cirrhosis of the liver and of hepatomas in mice with carbon tetrachloride. JNCI 3:19–41Google Scholar