Hemoperfusion over Small Liver Pieces for Liver Support
Hepatic assist using liver tissues with intact cellular structure has been previously investigated in a whole liver (Abouna et al. 1972; Eiseman et al. 1965), or in liver slices (Nose et al. 1975), small cellular masses (Eiseman et al. 1976), or cell suspension (Soyer et al. 1972). However, the preparation of these forms might require special instruments and the perfusion technique might be complicated. We have recently developed a device for hepatic assist with a simple technique using a fresh or preserved liver, which can also be used in combination with other devices.
KeywordsPhenol Albumin Urea Heparin Penicillin
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