Histomorphological Relations Between Myocarditis and Dilated Cardiomyopathy

  • E. G. J. Olsen
Conference paper

Abstract

The hearts of patients with dilated cardiomyopathy are overweight, and weights double the normal for the patient’s sex and height are not unusual. All chambers are often severely dilated and the myocardium is pale and flabby. Despite the hypertrophy, the ventricular and atrial walls are normal in thickness due to dilatation (Fig. 1). Fine fibrous replacement, frequently limited to the inner third of the myocardium, is often evident. The endocardium is non-specifically thickened, particularly in long-standing cases. Thrombus may or may not be superimposed [1,2]. The coronary vessels are usually normal and the pericardium shows no abnormalities.

Keywords

Lactate Tuberculosis Malaria Fibril Cardiomyopathy 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Olsen EGJ (1972) Cardiomyopathies. Cardiovasc Clin 4 No 2: 239–261Google Scholar
  2. 2.
    Olsen EGJ (1976) Pathologie der “primären” Kardiomyopathien. MMW118: 735–740Google Scholar
  3. 3.
    Olsen EGJ (1981) Pathology of congestive cardiomyopathy. In: Goodwin JF, Hialmarson A, Olsen EGJ (eds) Congestive cardiomyopathy, Kiruna, Sweden, 1980. Hässle, Mölndal, pp 66–74Google Scholar
  4. 4.
    Kobernick SD, Mandell GH, Zirkin RM, Hashimoto Y (1963) Succinic dehydrogenase deficiency in idiopathic cardiomegaly. Am J Pathol 43: 661–675PubMedGoogle Scholar
  5. 5.
    Baandrup U, Florio RA, Roters F, Olsen EGJ (1981) Electron microscopic investigation of endomyocardial biopsy samples in hypertrophy and cardiomyopathy. A semiquantitative study in 48 patients. Circulation 63: 1289–1298PubMedCrossRefGoogle Scholar
  6. 6.
    Olsen EGJ (1980) The pathology of the heart, 2nd edn. Macmillan, Basingstoke, pp 178–199Google Scholar
  7. 7.
    Mattingly TW (1973) Some historical notes on the development of the present state of knowledge of diseases of the myocardium. In: Fowles NO (ed) Myocardial diseases. Grune and Stratton, New York, pp 1–24Google Scholar
  8. 8.
    Olsen EGJ (1981) spivnIn Congestive cardiomyopathy, Kiruna, Sweden 1980. Goodwin JF, Hjalmarson A, Olsen EGJ (eds) Hässle, Mölndal, pp 122–123Google Scholar
  9. 9.
    Cambridge G, MacArthur CGC, Waterson AP, Goodwin JF, Oakley CM (1979) Antibodies to Coxsackie B viruses in congestive cardiomyopathy. Br Heart J 41: 692–696PubMedCrossRefGoogle Scholar
  10. 10.
    Daly K, Richardson PJ, Olsen EGJ, Capner P, Jackson G, Jewitt De (to be published) Acute myocarditis - diagnosis and treatment with immunosuppressive therapy.Google Scholar
  11. 11.
    Bolte HD, Schultheiss P (1978) Immunological results in myocardial diseases. Postgrad Med J 54: 500–503PubMedCrossRefGoogle Scholar
  12. 12.
    Fowles RE, Bieber CP, Stinson EB (1979) Defective in vitro suppressor cell function in idiopathic congestive cardiomyopathy. Circulation 59: 483–491PubMedGoogle Scholar
  13. 13.
    Eckstein R, Mempel W, Bolte HD (1982) Reduced suppressor cell activity in congestive cardiomyopathy and in myocarditis. Circulation 65: 1224–1229PubMedCrossRefGoogle Scholar
  14. 14.
    Das SK, Stein LD, Reynolds RT, Thebert P, Cassidy JT (1981) Immunologic studies in cardiomyopathy and pathophysiologic implications. In: Goodwin JF, Hjalmarson A, Olsen EGJ (eds) Congestive cardiomyopathy, Kiruna, Sweden 1980. Hässle, Molndal, pp 87–93Google Scholar
  15. 15.
    Amorim DS, Olsen EGJ (1982) Assessment of heart neurons in dilated (congestive) cardiomyopathy. Br Heart J 47: 11–18PubMedCrossRefGoogle Scholar
  16. 16.
    Klein H, Harmjanz D (1975) Effect of ethanol on the ultrastructure of human myocardium. Postgrad Med J 51: 325–329PubMedCrossRefGoogle Scholar
  17. 17.
    Olsen EGJ (1980) The pathology of the heart, 2nd edn. Macmillan, Basingstoke, pp 325–327Google Scholar
  18. 18.
    Richardson PJ., Atkinson L (1980) Enzyme activities in endomyocardial biopsy samples from patients with cardiomyopathy. Bolte HD (ed) Myocardial biopsy. Diagnostic significance. Springer, Berlin Heidelberg New York, pp 97–101CrossRefGoogle Scholar
  19. 19.
    Schultheiss HP, Bolte HD, Cyran J (1980) Lactate dehydrogenase isoenzyme pattern in myocardial biopsies of patients with congestive cardiomyopathy and with alcoholic cardiomyopathy — clinical and experimental results. In: Bolte HD (ed) Myocardial biopsy. Diagnostic significance. Springer, Berlin Heidelberg New York, pp 102–115CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • E. G. J. Olsen

There are no affiliations available

Personalised recommendations