Skip to main content

Oocytes from Adult Ovaries: First and Second Meiotic Divisions

  • Chapter
  • 36 Accesses

Abstract

The originally large number of germ cells, which reaches a maximum of approximately 6,000,000 during the fifth month postconception, is already being reduced in the fetal ovary because of cell degeneration; this process continues even in the adult ovary. The number of oocytes at the beginning of puberty has been estimated at 100,000, only 300–400 of which ever mature during the reproductive life span.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Austin, C.R., Short, R.V. (eds.): Reproduction in Mammals. Book 1: Germ Cells and Fertilization. Cambridge: Cambridge Univ. Press 1972.

    Google Scholar 

  • Biggers, J.D., Schuetz, A.W. (eds.): Oogenesis. Baltimore: University Park Press; London: Butterworths 1972.

    Google Scholar 

  • Blandau, R.J. (ed.): Aging Gametes, Their Biology and Pathology. Basel-New York: Karger 1975.

    Google Scholar 

  • Chandley, A.: Culture of mammalian oocytes. J. Reprod. Fert. (Suppl.) 14, 1–6 (1971).

    CAS  Google Scholar 

  • Channing, C.: Steroidogenesis and morphology of human ovarian cell types in tissue culture. J. Endocrinol. 45, 297–308 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Donahue, R.P.: Reproductive Genetics. Birth Defects: Orig. Art. Ser., 1974, Vol. X, Nr. 10, pp. 3–13.

    Google Scholar 

  • Eberle, P.: Die Chromosomenstruktur des Menschen in Mitosis und Meiosis. Fortschritte der Evolutionsforschung. Heberer, G. (ed.), Stuttgart: G. Fischer, 1966, Vol. II.

    Google Scholar 

  • Edwards, R.G.: Observations on meiosis in normal males and females. In: Human Population Cytogenetics, Jacobs, P.A., Price, W.H., Law, P. (eds.), Edinburgh: Edinburgh University Press, 1970, Pfizer Medical Monographs 5, pp. 9–21.

    Google Scholar 

  • Edwards, R.G., Fowler, R.F.: The genetics of human preimplantation development. In: Modern Trends in Human Genetics, Emery, A.E.H. ( ed.), London: A.E.H. (ed.), 1970, Vol. I, pp. 181–213.

    Google Scholar 

  • Edwards, R.G.: Maturation in vitro of human ovarian oocytes. Lancet 1965 II, 926–929.

    Google Scholar 

  • Ferguson-Smith, M.A.: Chromosomal satellite association. Lancet 1967 I/ 7500, 1156–1157.

    Google Scholar 

  • Ford, E.H.R.: Human Chromosomes. London-New York: Academic Press 1973

    Google Scholar 

  • Fowler, R.E., Edwards, R.G.: The genetics of early human development. In: Progress in Medical Genetics, Steinberg, A.G., Bearn, A.G. ( eds.), New York-London: A.G. (eds.), 1973, Vol. IX, pp. 49–112.

    Google Scholar 

  • Gondos, B., Zamboni, L.: Ovarian development: The functional importance of germ cell interconnections. Fertil. Steril. 20, 176–189 (1969).

    PubMed  CAS  Google Scholar 

  • Hamerton, J.L.: Human Cytogenetics. New York-London: Academic Press, 1971, Vols. I, I I.

    Google Scholar 

  • Hoehn, H., Sander, C., Sander, L.Z.: Aneusomie de recombinaison: Rearrangement between paternal chromosomes 4 and 18 yielding offspring with features of the 18q— syndrome. Ann. Genet. 14, 187–192 (1971).

    PubMed  CAS  Google Scholar 

  • Hultén, M.: Cytogenetic aspects of human male meiosis. Thesis, Stockholm, 1974.

    Google Scholar 

  • Jagiello, G., Ducayen, M., Fang, J.-S., Graffeo, J.: Cytogenetic observations in mammalian oocytes. In: Chromosomes Today V, Pearson, P.L., Lewis, K.L. (eds.), New York: Wiley, 1976, pp. 43–63.

    Google Scholar 

  • John, B., Lewis, K.R.: The Meiotic System. Protoplasmatologia. Berlin-Heidelberg-New York: Springer, 1965, Vol. VI.

    Google Scholar 

  • Kennedy, J.F., Donahue, R.P.: Human oocytes: Maturation in chemically defined media. Science 164, 1292–1293 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Knörr, K., Knörr-Gärtner, H.: Das Abortgeschehen unter genetischen Aspekten. Gynäkologe 10, 3–8 (1977).

    Google Scholar 

  • Knörr-Gärtner, H., Knörr, K., Haas, B.: Familiäre Translokation t (4q−; 18q +) mit verschiedenartigen unbalancierten Nachkommen. Humangenetik 21, 315–321 (1974).

    PubMed  Google Scholar 

  • Knörr, K., Uebele-Kallhardt, B.: Meiosestörungen menschlicher Eizellen nach Einwirkung endogener und exogener Noxen. In: Fortschritte der Fertilitätsforschung, Schirren, C. ( ed.), Berlin: C. (ed.), 1971, Vol. 2, pp. 28–33.

    Google Scholar 

  • Knörr, K., Uebele-Kallhardt, B.: Entwicklung und Reifung der Eizelle und ihre Störungen. In: Funktion und Pathologie des Ovariums, König, P.A., Probst, V. (eds.), Stuttgart: Enke, 1971, pp. 6–12.

    Google Scholar 

  • Langman, J.: Medical Embryology, 3rd ed., Baltimore: Williams and Wilkins.

    Google Scholar 

  • Lejeune, J., Berger, R.: Sur deux observations familiales de translocations complexes. Ann. Génét. 8, 21–29 (1965).

    PubMed  CAS  Google Scholar 

  • Nakogome, Y.: G-group chromosomes in satellite associations. Cytogenet. Cell Genet. 12, 336 (1972).

    Article  Google Scholar 

  • Nakogome, Y.: Participation of D-group chromosomes in satellite associations. Humangenetik 25, 235–236 (1974).

    Article  Google Scholar 

  • Nalbandov, A.V.: Interaction between oocytes and follicular cells. In: Oogenesis, Biggers, J.D., Schuetz, A.W. (eds.), Baltimore: University Park Press; London: Butterworths 1972, pp. 513–522.

    Google Scholar 

  • Paris Conference (1971): Standardization in Human Cytogenetics. Birth Defects Orig. Art. Ser. New York: The National Foundation 1972, Vol. 8, Nr. 7.

    Google Scholar 

  • Patil, S.R., Lubs, H.A.: Non-random association of human acrocentric chromosomes. Humangenetik 13, 157–159 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Pincus, G., Saunders, B.: The comparative behaviour of mammalian eggs in vivo and in vitro. II. The maturation of human ovarian ova. Anat. Rec. 75, 537–545 (1939).

    Article  Google Scholar 

  • Pinkerton, H.M., McKay, D.G., Adams, E.C., Hertig, A.T.: Development of the human ovary—a study using histochemical techniques. Obstet. Gynec. 18, 152–181 (1961).

    PubMed  CAS  Google Scholar 

  • Robinson, J.A.: Meiosis I non-disjunction as the main cause of trisomy 21. Hum. Genet. 39, 27–30 (1977).

    Article  PubMed  CAS  Google Scholar 

  • Sasaki, M., Makino, S.: The meiotic chromosomes of man. Chromosoma 16, 637–651 (1965).

    PubMed  CAS  Google Scholar 

  • Sele, B., Jalbert, P., van Cutsem, B., Lucas, M., Mouriquand, C., Bouchez, R.: Distribution of human chromosomes on the metaphase plate using banding techniques. Hum. Genet. 39, 39–63 (1977).

    Article  PubMed  CAS  Google Scholar 

  • Shettles, L.B.: Ovum Humanum. München-Berlin: Urban und Schwarzenberg 1960.

    Google Scholar 

  • Suzuki, S.: An Atlas of Mammalian Ova. Stuttgart: Thieme 1974.

    Google Scholar 

  • Tsafiri, A., Pomerantz, S.H., Channing, C.P.: Follicular control of oocyte maturation. In: Ovulation in the Human, Crosignani, P.G., Mishell, D.R. (eds.), London-New York: Academic Press, 1976, pp. 31–39.

    Google Scholar 

  • Uebele-Kallhardt, B., Knörr, K.: Meiotische Chromosomen der Frau. Humangenetik 12, 182–187 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Uebele-Kallhardt, B.: Mutation frequency in human oocytes. Humangenetik 16, 127–129 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Uebele-Kallhardt, B., Knörr, K.: Meiotic chromosome study in a human female translocation heterozygote. Humangenetik 26, 355–356 (1975a).

    Google Scholar 

  • Uebele-Kallhardt, B., Knörr, K.: Die Eizellen polycystischer menschlicher Ovarien. Arch. Gynäk. 218, 189–201 (1975b).

    Article  CAS  Google Scholar 

  • Wieczorek, V.: Chromosomenanomalien als Ursache von Fehlgeburten. München: Goldmann 1971.

    Google Scholar 

  • Yuncken, C.: Meiosis in the human female. Cytogenetics 7, 234–238 (1968).

    Article  PubMed  CAS  Google Scholar 

  • Zamboni, L.: Fine structure of human follicular oocytes maturing in vitro. In: Biology of Reproduction, Biggers, J.D. ( ed.), New York-London: J.D. (ed.), 1971, Vol. 5, p. 90.

    Google Scholar 

  • Zamboni, L.: Modulations of follicle cell-oocyte association in sequential stages of mammalian follicle development and maturation. In: Ovulation in the Human, Crosignani, P.G., Mishell, D.R. (eds.), London-New York: Academic Press, 1976, pp. 1–30.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Uebele-Kallhardt, BM. (1978). Oocytes from Adult Ovaries: First and Second Meiotic Divisions. In: Human Oocytes and Their Chromosomes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95328-6_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-95328-6_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-95330-9

  • Online ISBN: 978-3-642-95328-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics