Some Monoaminergic Mechanisms Controlling Sleep and Waking

  • M. Jouvet

Abstract

The nervous system is a super-organization comprising many sub-systems. This truism should be kept in mind when studying sleep mechanisms. The fact that rather limited, specific brain stem lesions are able to suppress either sleep or waking is a good reason to believe that certain systems are specialized to control the sleep-waking rhythm. This is a more promising approach to the problem of sleep-waking mechanisms than that which presupposes that every neuron possess a “built in” waking-sleep rhythm similar to the mysterious periodical firing shown by isolated neurons of Aplysia (Strumwasser, 1965).

Keywords

Dopamine Histamine Norepinephrine Acetylcholine Indole 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • M. Jouvet
    • 1
  1. 1.Department of Experimental MedicineSchool of MedicineLyonsFrance

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