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Fachübergreifende Aspekte der Hämostaseologie V pp 81–88Cite as

Protein-C-Pathway

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Zusammenfassung

Protein C ist das Proenzym einer Serinproteinase, wird von der Leber synthetisiert und Vitamin-K-abhängig mit γ-Carboxyglutamin-Gruppen (Gla) ausgestattet [23]. Die Aktivierung erfolgt durch Abspaltung eines aus 12 Aminosäuren bestehenden Aktivierungspeptids durch Thrombin und Proteasen ähnlicher Spezifität [24].

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Authors
  1. C.-E. Dempfle
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Editors and Affiliations

  1. Klinik für Anästhesiologie, Universität Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland

    Eike Martin

  2. Medizinische Klinik I, Universität Heidelberg, Bergheimer Straße 58, 69115, Heidelberg, Deutschland

    Peter Nawroth

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© 2002 Springer-Verlag Berlin Heidelberg

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Dempfle, CE. (2002). Protein-C-Pathway. In: Martin, E., Nawroth, P. (eds) Fachübergreifende Aspekte der Hämostaseologie V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-93394-3_6

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  • DOI: https://doi.org/10.1007/978-3-642-93394-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-43350-7

  • Online ISBN: 978-3-642-93394-3

  • eBook Packages: Springer Book Archive

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