Towards a Mathematical Model of Neurological Diseases Affecting the Extrapyramidal Motor System

  • Gerold Porenta
  • Peter Riederer
Conference paper
Part of the Lecture Notes in Medical Informatics book series (LNMED, volume 25)


Parkinson’s disease, a movement disorder affecting the extrapyrami da 1 motor system with akinesia, rigidity, and tremor as main symptoms, was among the first neurological diseases that could be shown to correlate with an abnormal distribution of a chemical substance in the brain. This discovery led to the development of Pharmacologically active drugs substantially improving treatment and prognosis of many neurological and psychiatric diseases. Thus, models of the chemical processes in the brain became important for clinical practice.


Caudate Nucleus Synaptic Cleft Presynaptic Vesicle Transmitter Substance Extrapyramidal System 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Gerold Porenta
    • 1
  • Peter Riederer
    • 2
  1. 1.Department of Medical Cybernetics and Artificial IntelligenceUniversity of Vienna, Medical SchoolWienAustria
  2. 2.Ludwig Boltzmann Institute of Clinical NeurobiologyNeurochemistry Group Lainz-HospitalWienAustria

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