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The Use of Mathematical Models and Computers in Treatment Evaluation

  • Conference paper
Medical Informatics Europe 84

Part of the book series: Lecture Notes in Medical Informatics ((LNMED,volume 24))

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Abstract

In a paper (1) delivered to the 1982 Medical Informatics Conference in Dublin, we described how a computerised data storage, retrieval and analysis system was developed for clinical research use in a special medical oncology unit. At that time, the system was implemented on main-frame computers. A 3-year project, funded jointly by the Department of Health and Social Security and the Department of Trade and Industry, is now underway to develop a (desk-top) micro-computer-based system to perform the functions now available on main-frame. It will do so in a more effective and user-friendly manner than in the past and will have sufficient flexibility to meet the specific needs of a variety of clinical environments.

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References

  1. Jackson, R. R. P., Birkhead, B. G., Gregory, W. M. Review of Modelling and Computing. In a Cancer Treatment Centre. Proceedings MIE ’82. International Conference on Medical Computing, Dublin.

    Google Scholar 

  2. Birkhead, B. G., Gregory, W. M. A Mathematical Model of the Effects of Drug Resistance in Cancer Chemotherapy. Mathematical Biosciences. To appear.

    Google Scholar 

  3. Skipper, H. E., Schabel, F. M. Jr., Wilcox, W. S. Experimental Evaluation of Potential Anticancer Agents XIII. On the Criteria and Kinetics Associated with “curability” of Experimental Leukaemia. Cancer Chemother. Rep. 35, 1–111.

    Google Scholar 

  4. Bruce, W. R., Meeker, B. E., Valeriote, F. A. Comparison of the Normal Haematopoietic and Transplanted Lymphoma Colony Forming Cells to Chemotherapeutic Agents Administered in Vivo. J. N. C. I. 37, 233–245.

    Google Scholar 

  5. Goldie, J. H., Coldman, A. J. A Mathematic Model for Relating the Drug Sensitivity of tumours to Their Spontaneous Mutation Rate. Cancer Treatment Reports, 63, 1727–1733.

    Google Scholar 

  6. Goldie, J. H., Coldman, A. J., Gcjdauskas, G. A. Rationale for the use of Alternating Non-Cross-Resistant Chemotherapy. Cancer Treatment Reports 6j6, 439–449.

    Google Scholar 

  7. Birkhead, B. G. Drug Resistance and the Chemotherapy of Residual Tumours. In preparation.

    Google Scholar 

  8. Jackson, R. R. P., Aspden, P. Treatment Evaluation-A Modelling Approach with Application to Acute Myeloid Leukaemia. J. Opl. Res. Soc.. Vol. 30, 1, 11–22.

    Google Scholar 

  9. Aspden, P., Jackson, R. R. P., Whitehouse, J. M. A. A Systems Approach to the Treatment Evaluation of Hodgkin’s Disease. Omega. The Int. Jnl. of Mgmt. Sci. Vol. 9, No. 5, 537–546.

    Google Scholar 

  10. Jackson, R. R. P., Birkhead, B. G., Bell, R., Lister, A., Gregory, W. M. Application of Jackson, Aspden Acute Myeloid Leukaemia Model. Jnl. Opl. Res. Soc. 33., 211–216.

    Google Scholar 

  11. Birkhead, B. G. A model of Remission Duration in Acute Myelogeous Leukaemia. In preparation.

    Google Scholar 

  12. Gregory, W. M., Bell, R., Jackson, R. R. P. An Automated Clinical Research and Data Analysis System. Computers and Biomedical Research. 14, 472–481.

    Google Scholar 

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© 1984 Springer-Verlag Berlin Heidelberg

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Jackson, R.R.P., Gregory, W.M., Birkhead, B.G. (1984). The Use of Mathematical Models and Computers in Treatment Evaluation. In: Roger, F.H., Willems, J.L., O’Moore, R.R., Barber, B. (eds) Medical Informatics Europe 84. Lecture Notes in Medical Informatics, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-93264-9_5

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  • DOI: https://doi.org/10.1007/978-3-642-93264-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-13374-2

  • Online ISBN: 978-3-642-93264-9

  • eBook Packages: Springer Book Archive

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