Automated Analysis of Papanicolaou Stained Cervical Specimens Using a Television-Based Analysis System (Leytas)

  • Johan S. Ploem
  • Anneke M. J. Van Driel-Kulker
Part of the Lecture Notes in Medical Informatics book series (LNMED, volume 17)


An image analysis program for automated screening of entire Papanicolaou stained slides, using a television based analysis system (LEYTAS), is described. A series of 45 specimens has been screened to test this program, that consists principally of nuclear contour finding, size and thresholding operations on the nucleus and artefact rejection procedures, using image transformations. The significance of the total number of alarms and the number of detected nuclei per 10.000 epithelial cells as discriminatory factors is discussed with regard to future improvements and developments.


Image Transformation Image Analysis Program Positive Specimen Cervical Cell Computer Terminal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Johan S. Ploem
    • 1
  • Anneke M. J. Van Driel-Kulker
    • 1
  1. 1.Department of Histochemistry and Cytochemistry, Sylvius LaboratoriesUniversity Medical CenterLeidenThe Netherlands

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