The King’s/Cambridge Trial
In 1842 Sir James Syme1, Professor of Surgery in Edinburgh stated; “the results of operations for carcinoma when the glands are affected is almost always unsatisfactory however perfectly they may have seemed to be taken away. The reason of this probably is that the glands do not participate in the disease unless the system is strongly disposed to it”. It has taken us well over a hundred years to rediscover this fundamental truth concerning the biological nature of carcinoma of the breast.
KeywordsEurope Neral Kelly Doyle Lawson
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- 1.Syme, J. (1842). Principles of Surgery. London, Bailiere.Google Scholar
- 3.Crile, G. Jr. (1967). A biological consideration of treatment of breast cancer. Fort Lauderdale,Florida, ThomasGoogle Scholar
- 4.Baum, M., (1977), The curability of breast cancer. In Breast Cancer Management — Early and Late. Ed. B.A. Stoll, London, William HeinemannGoogle Scholar
- 5.Griffiths, J.D. and Salsbury, A.J. (1965), Circulating cancer cells Thomas, Springfield, Illinois.Google Scholar
- 6.Fisher, B. (1970). Current problems in Surgery, Chicago, Year Book Publishers,Google Scholar
- 9.Stjernsward, J., Jondal, M. Vanky, F. et al. (1972) Lancet 1, 1352Google Scholar
- 12.Frieman, J.A. Chalmers, T.C., Smith, H., and Kuebler, R.R. (1978) The New England Journal of Medicine 299, 690.Google Scholar
- 16.Baum, M. (1979) Current controversy in the management of early carcinoma of the breast In Surgical Review, Editors Lumley amp; Craven, Pitman Medical, Tunbridge Wells.Google Scholar
- 18.Yorkshire Breast Cancer Group (197 7) British Medical Journal 2, 1196.Google Scholar
- 21.MacDonald, I. (1951). Surgery, Gynaecology amp; Obstetrics, 92, 443.Google Scholar