The King’s/Cambridge Trial

  • Michael Baum
Conference paper
Part of the Lecture Notes in Medical Informatics book series (LNMED, volume 4)

Abstract

In 1842 Sir James Syme1, Professor of Surgery in Edinburgh stated; “the results of operations for carcinoma when the glands are affected is almost always unsatisfactory however perfectly they may have seemed to be taken away. The reason of this probably is that the glands do not participate in the disease unless the system is strongly disposed to it”. It has taken us well over a hundred years to rediscover this fundamental truth concerning the biological nature of carcinoma of the breast.

Keywords

Europe Neral Kelly Doyle Lawson 

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References

  1. 1.
    Syme, J. (1842). Principles of Surgery. London, Bailiere.Google Scholar
  2. 2.
    Halsted, W.S. (1907). Annals of Surgery, 46, 1.PubMedCrossRefGoogle Scholar
  3. 3.
    Crile, G. Jr. (1967). A biological consideration of treatment of breast cancer. Fort Lauderdale,Florida, ThomasGoogle Scholar
  4. 4.
    Baum, M., (1977), The curability of breast cancer. In Breast Cancer Management — Early and Late. Ed. B.A. Stoll, London, William HeinemannGoogle Scholar
  5. 5.
    Griffiths, J.D. and Salsbury, A.J. (1965), Circulating cancer cells Thomas, Springfield, Illinois.Google Scholar
  6. 6.
    Fisher, B. (1970). Current problems in Surgery, Chicago, Year Book Publishers,Google Scholar
  7. 7.
    Hellstrom, I., Hellstrom, K.E., Sjogren, H.O. and Warner, G.A. (1971) International Journal of Cancer, 7, 1.CrossRefGoogle Scholar
  8. 8.
    Devitt, J.E. (1965). Canadian Medical Association Journal, 93, 289.PubMedGoogle Scholar
  9. 9.
    Stjernsward, J., Jondal, M. Vanky, F. et al. (1972) Lancet 1, 1352Google Scholar
  10. 10.
    Fisher, B., Slack, N.H., and Bross, I.D.J. (1969). Cancer, 24, 1071.PubMedCrossRefGoogle Scholar
  11. 11.
    Forrest, A.P.M. (1969). British Journal of Surgery 56, 782.PubMedCrossRefGoogle Scholar
  12. 12.
    Frieman, J.A. Chalmers, T.C., Smith, H., and Kuebler, R.R. (1978) The New England Journal of Medicine 299, 690.Google Scholar
  13. 13.
    Boag, J.W., Haybittle, J.L., Fowler, J.F. and Emery, E.W. (1971). British Journal of Radiology 44, 122.PubMedCrossRefGoogle Scholar
  14. 14.
    Cancer Research Campaign Working Party (1976). British Medical Journal, 1, 1035.CrossRefGoogle Scholar
  15. 15.
    Baum, M. (1975) Bulletin du Cancer, 62, 391.PubMedGoogle Scholar
  16. 16.
    Baum, M. (1979) Current controversy in the management of early carcinoma of the breast In Surgical Review, Editors Lumley amp; Craven, Pitman Medical, Tunbridge Wells.Google Scholar
  17. 17.
    Edwards, M.H., Baum, M. and Magarey, C.J. (1972). British Journal of Surgery, 59, 776.PubMedCrossRefGoogle Scholar
  18. 18.
    Yorkshire Breast Cancer Group (197 7) British Medical Journal 2, 1196.Google Scholar
  19. 19.
    Baum, M. and Coyle, P.J. (1977) Bulletin du Cancer 64, 603.PubMedGoogle Scholar
  20. 20.
    Fisher, B., Montague, E., Redmond, C. et al. (1977) Cancer 39, 2827.PubMedCrossRefGoogle Scholar
  21. 21.
    MacDonald, I. (1951). Surgery, Gynaecology amp; Obstetrics, 92, 443.Google Scholar
  22. 22.
    McKinnon, N.E. (1954). Lancet 1, 251.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • Michael Baum
    • 1
  1. 1.King’s College Hospital Medical SchoolUniversity of LondonUK

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