Genes are not perfectly unchanging entities: with a low, but not zero, frequency, a gene can change to another state, as a result of irradiation, chemical treatment, or simply because of an error in the process of chromosome replication. If such a change occurs in a line of cells which will give rise to gametes, then the new form of the gene can be transmitted to the offspring of the individuals in whom it arose. Thus an individual who received the alleles A i and A j at a locus at the time of his conception, can transmit a different allele, A k , to his offspring.
KeywordsMutation Rate Recurrent Mutation Neutral Mutation Congenital Dislocation Neutral Allele
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