The Development of Renal Function
During the first years of investigation of renal development, it was established that although the kidney performed some functions in the eutherian fetus it was both structurally and functionally immature. Fifty years on our knowledge of intra-uterine renal function is still very incomplete, primarily because of the technical difficulties associated with studies in utero. In contrast with eutherians, marsupial young are extremely immature at birth and, during the early part of pouch life, grow relatively slowly (Chapter 3). Most renal development, which is essentially similar to that seen in eutherians, occurs post-natally. In this chapter we argue that the developing marsupial is an excellent model for studies of renal development and describe some of our recent experimental studies.
KeywordsUrine Osmolality Renal Medulla Renal Development Concentrate Urine Excretory Organ
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