Skip to main content
SpringerLink
Log in
Book cover

Rheumatologie C pp 753–760Cite as

Das Sharp-Syndrom

  • Chapter

  • 24 Accesses

Part of the book series: Handbuch der inneren Medizin ((INNEREN 6,volume 6 / 2 / C))

Zusammenfassung

Synonyme: Sharp-Syndrom „mixed connective tissue disease“ (MCTD) (teilweise identisch mit veröffentlichten früheren Fällen unter folgenden Bezeichnungen: Überlappungs-Syndrome, Mischkollagenosen oder Kombinationskollagenosen)

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Bauer R, Schultzehrenburg U, Orfanos CE (1981) Progression of lupus erythematosus integumentalis into a mixed connective tissue disease. Hautarzt 1:23.

    Google Scholar 

  • Bennett RM, O’Connell DJ (1978) The arthritis of mixed connective tissue disease. Ann Rheum Dis 37:397.

    Article  PubMed  CAS  Google Scholar 

  • Bennett RM, O’Connell DJ (1980) Mixed connective tissue disease:A clinicopathological study of 20 cases. Semin Arthritis Rheum 10:25.

    Article  PubMed  CAS  Google Scholar 

  • Bennett RM, Spargo BH (1977) Immune complex nephropathy in mixed connective tissue disease. Am J Med 63:534.

    Article  PubMed  CAS  Google Scholar 

  • Bennett RM, Bong DA, Spargo BH (1978) Neuropsychiatric problems in mixed connective tissue disease. Am J Med 65:995.

    Google Scholar 

  • Bresnihan B, Bunn C, Snaith ML, Hughes GRV (1977) Antiribonucleoprotein antibodies in connective tissue diseases:Estimation by counterimmunelectrophoresis. Br Med J 1:610.

    Article  PubMed  CAS  Google Scholar 

  • Cryer PE, Kissane JM (1978) Mixed connective tissue disease. Am J Med 65:833.

    Article  Google Scholar 

  • Esther JH, Sharp GC, Agia G, Hurst DJ (1981) Pulmonary hypertension in patients with connective tissue disease and antibody to nuclear ribonucleoprotein. Arthritis Rheum [Suppl] 24:105.

    Google Scholar 

  • Eulderink F, Cats A (1981) Fatal primary pulmonary hypertension in mixed connective tissue disease. Z Rheumatol 40:25.

    PubMed  CAS  Google Scholar 

  • Fuller TJ, Richman AV, Auerbach D, Alexander RW, Lottenburg R, Longley S (1977) Immunecomplex glomerulonephritis in a patient with mixed connective tissue disease. Am J Med 62:762.

    Article  Google Scholar 

  • Gilliam JN, Prystowsky SD (1977a) Mixed connective tissue disease syndrome:The cutaneous manifestations of patients with epidermal nuclear staining and high titer antibody to RNase sensitive extractable nuclear antigen (ENA). Arch Dermatol 113:583.

    Article  PubMed  CAS  Google Scholar 

  • Gilliam JN, Prystowsky SD (1977 b) Conversion of discoid lupus erythematosus to mixed connective tissue disease. J Rheumatol 4:165.

    PubMed  CAS  Google Scholar 

  • Grossman LA, Li JKH (1981) Myocardial involvement in mixed connective tissue disease. NY State J Med 81:379.

    CAS  Google Scholar 

  • Halla JT, Hardin JG (1978) Clinical features of the arthritis of mixed connective tissue disease. Arthritis Rheum 21:497.

    Article  PubMed  CAS  Google Scholar 

  • Hamburger M, Hodes S, Barland P (1977) The incidence and clinical significance of antibodies to extractable nuclear antigens. Am J Med Sci 273:21.

    Article  PubMed  CAS  Google Scholar 

  • Hench PK, Edington TS, Tan EM (1975) The evolving clinical spectrum of mixed connective tissue disease (MCTD). Arthritis Rheum 18:404.

    Google Scholar 

  • Hohmeister R (1979) Mixed connective tissue disease:eine Lupus-Variante. Aktuel Rheumatol 4:197.

    Google Scholar 

  • Horn JR, Kapur JJ, Walker SE (1978) Mixed connective tissue disease in sibblings. Arthritis Rheum 21:709.

    Article  PubMed  CAS  Google Scholar 

  • Hughes GRV (1979) Mixed connective tissue disease. In:Connective tissue diseases, 2nd edn. Blackwell, Oxford, pp 171–177.

    Google Scholar 

  • Jones MB, Osterholm RK, Wilson RB, Martin FH, Commers JR, Bachmayer JD (1978) Fatal pulmonary hypertension and resolving immunecomplex glomerulonephritis in mixed connective tissue disease:case report and review of the literature. Am J Med 65:855.

    Article  PubMed  CAS  Google Scholar 

  • Kitridou RC, Akmal M, Ehresmann GR, Quismorio FP, Massry S (1980) Nephropathy in mixed connective tissue disease. Arthritis Rheum 23:704.

    Google Scholar 

  • Lagarde P, Lamotte-Barillon S (1979) Neuropathie trigeminale isolée revelatrice d’un syndrome de Sharp ou MCTD (mixed connective tissue disease). Ann Med Interne (Paris) 130:337.

    CAS  Google Scholar 

  • Leibfarth JH, Persellin RH (1976) Characteristics of patients with serum antibodies to extractable nuclear antigens. Arthritis Rheum 19:851.

    Article  PubMed  CAS  Google Scholar 

  • Lessard JA, Terrell K, Fine R, Pope RM (1981) The prevalence of progressive lung involvement in patients with high titer antiribonucleoprotein. Arthritis Rheum [Suppl] 24:105.

    Google Scholar 

  • Michels H, Schuchmann L (1980) Das Sharp-Syndrom (MCTD), eine besondere Form der Kollagenose im Kindesalter. Klin Pädiatr 192:389.

    Article  PubMed  CAS  Google Scholar 

  • Müller W (1980) Mixed connective tissue disease (Sharp-Syndrom). Therapiewoche 30:4563.

    Google Scholar 

  • Norman DA, Fleischmann RM (1978) Gastrointestinal systemic sclerosis in serologie mixed connective tissue disease. Arthritis Rheum 21:811.

    Article  PubMed  CAS  Google Scholar 

  • Oxenhandler R, Hart M, Corman L, Sharp G, Adelstein E (1977) Pathology of sceletal muscle in mixed connective tissue disease. Arthritis Rheum 50:985.

    Article  Google Scholar 

  • Parker MD (1973) Ribonucleoprotein antibodies:Frequencies and clinical significance in systemic lupus erythematosus, Scleroderma, and mixed connective tissue disease. J Lab Clin Med 82:769.

    PubMed  CAS  Google Scholar 

  • Ramos-Niembro F, Alarcón-Segovia D (1978) Familial aspects of mixed connective tissue disease (MCTD). J Rheumatol 5:433.

    PubMed  CAS  Google Scholar 

  • Rosenthal M (1978) Sharp-Syndrom (mixed connective tissue disease) bei Kindern. Helv Paediatr Acta 33:251.

    PubMed  CAS  Google Scholar 

  • Seelig HP (1981) Das Sharp-Syndrom (Mischkollagenosen). Immun Infekt 9:223.

    PubMed  CAS  Google Scholar 

  • Segond P, Yeni P, Jaquot JM, Massias P (1978) Severe autoimmune anemia and thrombopenia in mixed connective tissue disease. Arthritis Rheum 21:995.

    Article  PubMed  CAS  Google Scholar 

  • Sharp GC (1975a) Mixed connective tissue disease. Bull Rheum Dis 25:828.

    CAS  Google Scholar 

  • Sharp GC (1975 b) Mixed connective disease — overlap syndromes. Clin Rheum Dis 1:561.

    Google Scholar 

  • Sharp GC (1977) Mixed connective tissue disease. Arthritis Rheum [Suppl] 20:181.

    Google Scholar 

  • Sharp GC (1978) Mixed connective tissue disease. In:Samter M (ed) Immunological diseases, 3rd edn. Little, Brown, Boston, pp 1142–1150.

    Google Scholar 

  • Sharp GC (1979) Mixed connective tissue disease. In:McCarty DJ (ed) Arthritis and allied conditions, 9th edn. Lea & Febiger, Philadelphia, pp 737–741.

    Google Scholar 

  • Sharp GC (1981) Mixed connective tissue disease and overlap syndromes. In:Kelley WN, Harris ED, Ruddy S, Sledge CB (eds) Textbook of Rheumatology. Saunders, Philadelphia London Toronto, pp 1151–1161.

    Google Scholar 

  • Sharp GC, Irvin WS, Tan EM, Gould RG, Holman HR (1972) Mixed connective tissue disease — an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med 52:148.

    Article  PubMed  CAS  Google Scholar 

  • Sharp GC, Irvin WS, May CM, Holman HR, McDuffie FC, Hess EV, Schmidt FR (1976) Association of antibodies to ribonucleoprotein and Sm antigens with mixed connective-tissue disease, systemic lupus erythematosus and other rheumatic diseases. N Engl J Med 295:1149.

    Article  PubMed  CAS  Google Scholar 

  • Singsen B, Kornreich H, King K, Bernstein B, Hanson V, Tan E (1976) Mixed connective tissue disease (MCTD) in children. Arthritis Rheum 19:822.

    Google Scholar 

  • Singsen BH, Bernstein BH, Kornreich HK, King KK, Hanson V, Tan EM (1977) Mixed connective tissue disease in childhood. J Pediatr 90:893.

    Article  PubMed  CAS  Google Scholar 

  • Singsen BH, Landing B, Wolfe JF, Bernstein B, Oxenhandler RW, Sharp GC, Hanson V (1978) Histologic evaluation of mixed connective tissue disease in children and adults. Arthritis Rheum 21:593.

    Article  Google Scholar 

  • Takano M (1978) Clinical significance of antibodies to nuclear ribonucleoprotein in collagen diseases. Ryumachi 18:256.

    PubMed  CAS  Google Scholar 

  • Winn D, Gerhardt D, Winship D, Sharp GC (1976) Esophageal function in steroid treated patients with mixed connective tissue disease (MCTD). Clin Res 24:545 A.

    Google Scholar 

  • Wolfe JF, Kingsland J, Lindberg D, Sharp GC (1977) Disease pattern in patients with antibodies only to nuclear ribonucleoprotein (RNP). Clin Res 25:488 A.

    Google Scholar 

  • Zuckner J, Baldassare A, Weiss T, Auclair R (1977) Mixed connective tissue disease in children. Arthritis Rheum 20:364.

    Google Scholar 

Download references

Authors
  1. G. L. Bach
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Pathologisches Institut, Kantonsspital, CH-6004, Luzern, Schweiz

    M. Aufdermaur

  2. Klinik Herzoghöhe, Kulmbacherstraße 103, D-8580, Bayreuth, Deutschland

    G. L. Bach

  3. Klinik für innere und physikalische Medizin, Staatl. Rheumakrankenhaus, Rottenbachtalstraße 5, D-7570, Baden-Baden, Deutschland

    J.-M. Engel

  4. Rheumatologie, Ärztehaus, Seegartenstraße 1, D-6990, Bad Mergentheim, Deutschland

    R. Filchner (Ärztin für innere Krankheiten) (Ärztin für innere Krankheiten)

  5. Kinderklinik, Schwalbacher Straße 62, D-6200, Wiesbaden, Deutschland

    F. Graser (Chefarzt der Städt.) (Chefarzt der Städt.)

  6. Kurklinik Niedersachsen, Hauptstraße 59, D-3052, Bad Nenndorf, Deutschland

    E. Gundel

  7. Medizinische Poliklinik, Universität München, Pettenkoferstraße 8 a, D-8000, München 2, Deutschland

    H. Hess

  8. Klinik für Innere u. Psychosomatische Erkrankungen, Hohenfeld-Klinik Pitzer KG., Hohenfeldstr. 12-14, D-6722, Camberg/Taunus, Deutschland

    F. Husmann

  9. Klinisches Institut für Herzinfarktforschung, Medizinische Universitäts-Klinik, Bergheimer Straße 53, D-6900, Heidelberg, Deutschland

    H. Kather

  10. Universitäts-Klinik für Dermatologie und Venerologie in Graz, Auenbruggerplatz 8, A-8036, Graz, Österreich

    H. Kerl  & H. Kresbach  & 

  11. Rehabilitationszentrum für rheumatische Erkrankungen und Herz-Kreislaufkrankheiten der PVArb., Ludwig Boltzmann-Institut für Rehabilitation interner Erkrankungen, Thorerstraße 26, A-5760, Saalfelden/Salzburg, Österreich

    G. Klein

  12. Neurologische Abteilung, Bezirkskrankenhaus, D-8013, Haar bei München, Deutschland

    W. Krämer

  13. Neurologische Abt. des Bezirkskrankenhauses, Universitätsstr. 84, D-8400, Regensburg 9, Deutschland

    H. Leinisch

  14. Hautklinik Linden, Medizinischen Hochschule und der Landeshauptstadt Hannover, Ricklinger Str. 5, D-3000, Hannover 91, Deutschland

    S. Marghescu

  15. Neurologische Klinik des Bezirks Niederbayern, D-8360, Deggendorf 5 Mainkofen, Deutschland

    R. Maurach

  16. Klinik Wendelstein der BFA, Rheumazentrum, Kolbermoorer Str. 56, D-8202, Bad Aibling, Deutschland

    W. Miehle

  17. Abt. Pathologie, Universität, Oberer Eselsberg, D-7900, Ulm, Deutschland

    W. Mohr

  18. II. Medizinische Klinik des Rheuma-Zentrums Bad Abbach, D-8403, Bad Abbach, Deutschland

    H. Müller-Fassbender

  19. Friedrich-Baur-Institut, Universität München, Ziemssenstr. 1 a, D-8000, München 2, Deutschland

    D. Pongratz

  20. Neurologische Abt. des Bezirkskrankenhauses Regensburg, Universitätsstr. 84, D-8400, Regensburg 19, Deutschland

    W. Schmidt-Vanderheyden

  21. I. Medizinische Klinik des Rheuma-Zentrums Bad Abbach, D-8403, Bad Abbach, Deutschland

    P. Schneider  & H. Mathies  & 

  22. Gastroenterologische Abteilung, Medizinische Universitäts-Klinik, Bergheimer Str. 58, D-6900, Heidelberg 1, Deutschland

    B. Simon

  23. Medizinische Abteilung des LKH Feldbach, A-8330, Feldbach, Deutschland

    G. Stöckl

  24. Orthopädische Poliklinik der Universität, Pettenkoferstr. 8 a, D-8000, München 2, Deutschland

    S. Stotz

  25. Klinik, Max-Planck-Institut für Psychiatrie, Kraepelinstr. 10, D-8000, München 40, Deutschland

    F. Strian

  26. Rheumaklinik und Institut für physikalische Therapie, Universitätsspital Zürich, Gloriastr. 25, CH-8006, Zürich, Schweiz

    F. J. Wagenhäuser

  27. Werdstr. 34, CH-8004, Zürich, Schweiz

    A. Weintraub

  28. Orthopädische Klinik des Rheuma-Zentrums Bad Abbach, D-8403, Bad Abbach/Regensburg, Deutschland

    D. Wessinghage

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bach, G.L. (1983). Das Sharp-Syndrom. In: Aufdermaur, M., et al. Rheumatologie C. Handbuch der inneren Medizin, vol 6 / 2 / C. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-88228-9_37

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-88228-9_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-88229-6

  • Online ISBN: 978-3-642-88228-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation