Purification, Properties, and Composition of α1-Trypsin Inhibitor from Human Plasma

  • L. F. Kress
  • M. LaskowskiSr.
Part of the Bayer-Symposium book series (BAYER-SYMP, volume 5)

Abstract

Although plasma contains several fractions capable of inhibiting trypsin [1], the predominant amount of inhibitor (90%) is found in the α1globulin fraction [2]. Several investigators have reported partial purification of the α1trypsin inhibitor using a variety of preparative techniques [1–10]. The specific activity of these preparations ranged from 0.2 to 0.6 μg trypsin (uncorrected for active trypsin) inhibited per μg inhibitor.

Keywords

Cellulose Carbohydrate Tyrosine Sedimentation Fractionation 

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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • L. F. Kress
    • 1
  • M. LaskowskiSr.
    • 1
  1. 1.Laboratory of EnzymologyRoswell Park Memorial InstituteBuffaloUSA

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