General Indroduction to Isolation and Characterization of Peroxisomes
Peroxisomes are ubiquitous cell organelles [1,4]. Most cells have spherical or spheroidal peroxisomes with a diameter between 0.2 and 1 μm, but in some tissues or organisms, like in the germinating spores of moss , in sebaceous glands , in mouse liver , in regenerating rat liver , and in the epithelium of kidney tubules , irregularly shaped profiles have been demonstrated. Peroxisomes are surrounded by a single membrane limiting the so called matrix compartment, which comprises the bulk of peroxisomal enzymes. Whereas most of these matrix enzymes are quite soluble, urate oxidase tends to aggregate, forming the crystalline “core” or “nucleoid” of peroxisomes.
KeywordsSebaceous Gland Urate Oxidase Peroxisomal Enzyme Straight Chain Fatty Acid Preputial Gland
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