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General Indroduction to Isolation and Characterization of Peroxisomes

  • P. P. Van Veldhoven
  • A. Völkl
Part of the Springer Laboratory book series (SLM)

Abstract

Peroxisomes are ubiquitous cell organelles [1,4]. Most cells have spherical or spheroidal peroxisomes with a diameter between 0.2 and 1 μm, but in some tissues or organisms, like in the germinating spores of moss [8], in sebaceous glands [2], in mouse liver [3], in regenerating rat liver [10], and in the epithelium of kidney tubules [11], irregularly shaped profiles have been demonstrated. Peroxisomes are surrounded by a single membrane limiting the so called matrix compartment, which comprises the bulk of peroxisomal enzymes. Whereas most of these matrix enzymes are quite soluble, urate oxidase tends to aggregate, forming the crystalline “core” or “nucleoid” of peroxisomes.

Keywords

Sebaceous Gland Urate Oxidase Peroxisomal Enzyme Straight Chain Fatty Acid Preputial Gland 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Böck P, Kramar R, Pavelka M (1980) Peroxisomes and related particles in animal tissues. Cell Biol. Monographs. Vol 7. Springer-Verlag, New YorkGoogle Scholar
  2. 2.
    Gorgas K (1984) Peroxisomes in sebaceous glands. V. Complex peroxisomes in mouse preputial gland: serial sectioning and three-dimensional reconstruction studies. Anat Embryol 169:261–270PubMedCrossRefGoogle Scholar
  3. 3.
    Gorgas K. (1985) Serial section analysis of mouse hepatic peroxisomes. Anat Embryol 172:21–32PubMedCrossRefGoogle Scholar
  4. 4.
    Hruban Z, Rechcigl M Jr. (1969) Microbodies and related particles. Int Rev Cytol. Suppl. 1. Academic, New YorkGoogle Scholar
  5. 5.
    Lock EA, Mitchell AM, Elcombe CR (1989) Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu Rev Pharmacol Toxicol 29:145–163PubMedCrossRefGoogle Scholar
  6. 6.
    Mannaerts GP, Van Veldhoven PP (1993) Metabolic role of mammalian peroxisomes. In: Peroxisome Importance in Biology and Medicine (Eds. Gibson and Lake), Taylor and Francis, London (in press)Google Scholar
  7. 7.
    Mannaerts GP, Van Veldhoven PP (1992) Role of peroxisomes in mammalian metabolism. Cell Biochem Funct 10:141–151PubMedCrossRefGoogle Scholar
  8. 8.
    Pais MSS, Carrapico F (1982) Microbodies. A membrane compartment. Ann. N. Y. Acad Sci USA 306:510–513Google Scholar
  9. 9.
    Van den Bosch H, Schutgens RBH, Wanders RJA, Tager J (1992) Biochemistry of peroxisomes. Annu Rev Biochem 61:157–197PubMedCrossRefGoogle Scholar
  10. 10.
    Yamamoto K, Fahimi HD (1987) Three-dimensional reconstruction of a peroxisomal reticulum in regenerating rat liver: evidence of interconnections between heterogeneous segments. J Cell Biol 105:713–722PubMedCrossRefGoogle Scholar
  11. 11.
    Zaar K (1992) Structure and function of peroxisomes in the mammalian kidney. Eur J Cell Biol 59:233–254PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • P. P. Van Veldhoven
  • A. Völkl

There are no affiliations available

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